UAMS Immunology Final Review with Compete Solutions
1. Name 4 cardinal signs of inflamma- redness, heat, swelling, pain, loss of function
tion.
2. Which cell is increased in inflammation PMNs; neutrophil
3. Diapedesis the passage of blood cells through the intact walls
of the capillaries, typically accompanying inflam-
mation.
4. What causes swelling in acute inflam- Leakage of fluid from postcapillary venules into
mation? the interstitial space
5. Name 2 substances that enhance IgG
phagocytosis C3b
Opsonins
6. The pseudopod that surrounds a parti- Phagolysosome
cle within a cell is called a ?
7. After the macrophage digests the Exocytosis
material with enzymes, the excretion
process is called ?
8. A man and a woman have the follow- A2, B17, Cw3, DR5 / A9, B17, Cw6, DR3
ing genotypes: A2, B17, Cw3, DR5 / A36, B13, Cw11, DR8
Woman's: A2, B17, Cw3, DR5 & A10, A10, B15, Cw7, DR1 / A9, B17, Cw6, DR3
B15, Cw7, DR1 A10, B15, Cw7, DR1 / A36, B13, Cw11, DR8
Man's: A9, B17, Cw6, DR3 & A36, B13,
Cw11, DR8
List the 4 most likely genotypes of their
children:
9.
, UAMS Immunology Final Review with Compete Solutions
A man and a woman have the follow- A15, B25, Cw6, DR1 / A15, B29, Cw8, DR13
ing genotypes: A15, B25, Cw6, DR1 / A6, B5, Cw1, DR18
Woman's: A15, B25, Cw6, DR1 & A7, B5, A7, B5, Cw17, DR11 / A15, B29, Cw8, DR13
Cw17, DR11 A7, B5, Cw17, DR11 / A6, B5, Cw1, DR18
Man's: A15, B29, Cw8, DR13 & A6, B5,
Cw1, DR18
List the 4 most likely genotypes of their
children:
10. Taq polymerase and a Binds to each priming site; synthesizes
new DNA strand
11. What are primers used for in the PCR Bind and bracket the target DNA sequence to be
procedure? copied.
12. What is the known in Direct Fluores- ABY
cent ABY testing?
13. What is the unknown in Direct Fluores- AGN
cent ABY testing?
14. What is the reporter molecule in Direct ABY
Fluorescent ABY testing?
15. What is known in the Indirect Fluores- ABY or AGN
cent test?
16. The reporter molecule in Direct Fluo- Fluorescein
rescent ABY testing is labeled with:
17. What is the unknown in the Indirect ABY or AGN
Fluorescent test?
18. ABY
, What is the reporter molecule in Indi-
rect Fluorescent test?
19. The reporter molecule in indirect Fluo- Fluorescein
rescent testing is labeled with:
20. Interferon A cytokine with antiviral activity
21. Antigen A substance that binds with antibody but may not
evoke an immune response
22. Immunogen A substance that induces an immune response
23. Opsonin Coats foreign particles and enhances phagocyto-
sis
24. Immunology The study of host reactions when foreign sub-
stances are introduced
25. TNF Cytokine that mediates Gram negative infections;
recruits WBCs
26. Epitope Antibody binding site; single antigen site
27. Autocrine Cytokine that acts on the cell that produces it
28. Chemokines The cytokines that induce chemotaxis to assist in
destroying microorganisms
29. Genotype Known haplotypes of an individual
30. Chemotaxis Movement of WBCs to an area of inflammation in
response to chemical mediators
31. T-dependant
, Proteins that need T cell involvement to produce
immune responses
32. T-independant Nonprotein antigen that does not need T cells to
produce an immune response
33. Phenotype The expression of genes present in an individual
34. MHC major histocompatibility complex; Set of genes
inside chromosomes that encode for molecules
recognized by T cells
35. Gating Instrument setting that allows analysis of a partic-
ular set of cells
36. Memory Heightened response with re-exposure
37. Interleukin A type of cytokine that enables communication
between WBCs
38. MALT Tissue associated with GI, respiratory & urogenital
tract (incl. tonsils & appendix)
39. Haptens Non-immunogenic unless complexed with a larg-
er carrier
40. Class II MHC Molecule that transports antigen to cell surface
for presentation to CD4 T cells
41. Innate Protection by means of normally present body
functions
42. Anamnestic Secondary antibody response
43. CD
1. Name 4 cardinal signs of inflamma- redness, heat, swelling, pain, loss of function
tion.
2. Which cell is increased in inflammation PMNs; neutrophil
3. Diapedesis the passage of blood cells through the intact walls
of the capillaries, typically accompanying inflam-
mation.
4. What causes swelling in acute inflam- Leakage of fluid from postcapillary venules into
mation? the interstitial space
5. Name 2 substances that enhance IgG
phagocytosis C3b
Opsonins
6. The pseudopod that surrounds a parti- Phagolysosome
cle within a cell is called a ?
7. After the macrophage digests the Exocytosis
material with enzymes, the excretion
process is called ?
8. A man and a woman have the follow- A2, B17, Cw3, DR5 / A9, B17, Cw6, DR3
ing genotypes: A2, B17, Cw3, DR5 / A36, B13, Cw11, DR8
Woman's: A2, B17, Cw3, DR5 & A10, A10, B15, Cw7, DR1 / A9, B17, Cw6, DR3
B15, Cw7, DR1 A10, B15, Cw7, DR1 / A36, B13, Cw11, DR8
Man's: A9, B17, Cw6, DR3 & A36, B13,
Cw11, DR8
List the 4 most likely genotypes of their
children:
9.
, UAMS Immunology Final Review with Compete Solutions
A man and a woman have the follow- A15, B25, Cw6, DR1 / A15, B29, Cw8, DR13
ing genotypes: A15, B25, Cw6, DR1 / A6, B5, Cw1, DR18
Woman's: A15, B25, Cw6, DR1 & A7, B5, A7, B5, Cw17, DR11 / A15, B29, Cw8, DR13
Cw17, DR11 A7, B5, Cw17, DR11 / A6, B5, Cw1, DR18
Man's: A15, B29, Cw8, DR13 & A6, B5,
Cw1, DR18
List the 4 most likely genotypes of their
children:
10. Taq polymerase and a Binds to each priming site; synthesizes
new DNA strand
11. What are primers used for in the PCR Bind and bracket the target DNA sequence to be
procedure? copied.
12. What is the known in Direct Fluores- ABY
cent ABY testing?
13. What is the unknown in Direct Fluores- AGN
cent ABY testing?
14. What is the reporter molecule in Direct ABY
Fluorescent ABY testing?
15. What is known in the Indirect Fluores- ABY or AGN
cent test?
16. The reporter molecule in Direct Fluo- Fluorescein
rescent ABY testing is labeled with:
17. What is the unknown in the Indirect ABY or AGN
Fluorescent test?
18. ABY
, What is the reporter molecule in Indi-
rect Fluorescent test?
19. The reporter molecule in indirect Fluo- Fluorescein
rescent testing is labeled with:
20. Interferon A cytokine with antiviral activity
21. Antigen A substance that binds with antibody but may not
evoke an immune response
22. Immunogen A substance that induces an immune response
23. Opsonin Coats foreign particles and enhances phagocyto-
sis
24. Immunology The study of host reactions when foreign sub-
stances are introduced
25. TNF Cytokine that mediates Gram negative infections;
recruits WBCs
26. Epitope Antibody binding site; single antigen site
27. Autocrine Cytokine that acts on the cell that produces it
28. Chemokines The cytokines that induce chemotaxis to assist in
destroying microorganisms
29. Genotype Known haplotypes of an individual
30. Chemotaxis Movement of WBCs to an area of inflammation in
response to chemical mediators
31. T-dependant
, Proteins that need T cell involvement to produce
immune responses
32. T-independant Nonprotein antigen that does not need T cells to
produce an immune response
33. Phenotype The expression of genes present in an individual
34. MHC major histocompatibility complex; Set of genes
inside chromosomes that encode for molecules
recognized by T cells
35. Gating Instrument setting that allows analysis of a partic-
ular set of cells
36. Memory Heightened response with re-exposure
37. Interleukin A type of cytokine that enables communication
between WBCs
38. MALT Tissue associated with GI, respiratory & urogenital
tract (incl. tonsils & appendix)
39. Haptens Non-immunogenic unless complexed with a larg-
er carrier
40. Class II MHC Molecule that transports antigen to cell surface
for presentation to CD4 T cells
41. Innate Protection by means of normally present body
functions
42. Anamnestic Secondary antibody response
43. CD
