HESI Exit Family Nurse Practitioner (FNP)
Review Questions & Answers | Latest
Updated Study Guide for Certification Exam
Prep
• This study guide features 200 high-yield HESI Exit FNP practice questions with
boldly highlighted correct answers, lettered options A–E, and detailed EXPERT
RATIONALE to reinforce clinical reasoning across all major FNP exam domains.
• Use this material by reading each question independently before checking the
answer, then study the EXPERT RATIONALE carefully to understand the "why"
behind every correct choice — this builds the pattern recognition needed for
certification success.
HESI EXIT FAMILY NURSE PRACTITIONER (FNP)
Review Questions & Answers | Latest Updated Study Guide
SECTION 1: HEALTH PROMOTION & DISEASE PREVENTION
1. A 50-year-old male presents for a routine checkup. He has no symptoms
and no significant family history. According to the USPSTF, at what age should
average-risk colorectal cancer screening begin?
A) 40 years
B) 45 years
C) 50 years
D) 55 years
E) 60 years
CORRECT ANSWER: B) 45 years
,EXPERT RATIONALE: The USPSTF updated its recommendation in 2021, lowering the
starting age for colorectal cancer screening in average-risk adults from 50 to 45 years
due to increasing incidence in younger populations.
2. A 65-year-old woman asks about osteoporosis screening. Which of the
following is the most appropriate recommendation by the USPSTF?
A) Screen all women starting at age 60
B) Screen all women starting at age 55
C) Screen all women at age 65 and younger postmenopausal women at increased
risk
D) Screen only women with a family history of osteoporosis
E) Screen only women who have had a fracture
CORRECT ANSWER: C) Screen all women at age 65 and younger
postmenopausal women at increased risk
EXPERT RATIONALE: USPSTF recommends screening for osteoporosis with bone
measurement testing in women aged 65 and older, and in postmenopausal women
under 65 who are at increased risk as determined by a formal risk assessment tool.
3. Which vaccine is recommended for adults aged 50 years and older to
prevent herpes zoster?
A) Zostavax (live zoster vaccine)
B) Varivax (varicella vaccine)
C) Shingrix (recombinant zoster vaccine)
D) MMR vaccine
E) Pneumovax 23
CORRECT ANSWER: C) Shingrix (recombinant zoster vaccine)
,EXPERT RATIONALE: Shingrix is the preferred vaccine for prevention of herpes zoster
and its complications in adults aged 50 and older. It is given in two doses and has over
90% efficacy, superior to the older Zostavax.
4. A 35-year-old woman with no risk factors asks about cervical cancer
screening. What is the current USPSTF recommendation?
A) Pap smear every year
B) Pap smear every 2 years
C) Pap smear every 3 years, or co-testing every 5 years
D) HPV testing alone every 5 years starting at age 30
E) No screening until age 40
CORRECT ANSWER: C) Pap smear every 3 years, or co-testing every 5 years
EXPERT RATIONALE: USPSTF recommends cervical cancer screening with Pap smear
alone every 3 years for women 21–65, or with high-risk HPV testing alone every 5 years,
or co-testing (Pap + HPV) every 5 years for women 30–65.
5. A 55-year-old male with a 30-pack-year history of smoking currently
smokes. Which screening does the USPSTF recommend?
A) Chest X-ray annually
B) Sputum cytology annually
C) Low-dose CT scan of the chest annually
D) Bronchoscopy every 2 years
E) PET scan every 3 years
CORRECT ANSWER: C) Low-dose CT scan of the chest annually
, EXPERT RATIONALE: USPSTF recommends annual low-dose CT (LDCT) screening for lung
cancer in adults aged 50–80 who have a 20-pack-year smoking history and currently
smoke or have quit within the past 15 years.
6. Which of the following is the most important modifiable risk factor for
cardiovascular disease in a primary care patient?
A) Age
B) Family history
C) Hypertension
D) Gender
E) Ethnicity
CORRECT ANSWER: C) Hypertension
EXPERT RATIONALE: Hypertension is the single most important modifiable risk factor for
cardiovascular disease. It can be controlled with lifestyle modifications and
pharmacotherapy, making it a primary target in preventive care.
7. A 40-year-old male asks about abdominal aortic aneurysm (AAA) screening.
According to the USPSTF, who should be screened?
A) All males aged 40 and older
B) All females aged 65 and older who smoke
C) Males aged 65–75 who have ever smoked
D) Males and females aged 65 who have ever smoked
E) No screening is recommended
CORRECT ANSWER: C) Males aged 65–75 who have ever smoked
Review Questions & Answers | Latest
Updated Study Guide for Certification Exam
Prep
• This study guide features 200 high-yield HESI Exit FNP practice questions with
boldly highlighted correct answers, lettered options A–E, and detailed EXPERT
RATIONALE to reinforce clinical reasoning across all major FNP exam domains.
• Use this material by reading each question independently before checking the
answer, then study the EXPERT RATIONALE carefully to understand the "why"
behind every correct choice — this builds the pattern recognition needed for
certification success.
HESI EXIT FAMILY NURSE PRACTITIONER (FNP)
Review Questions & Answers | Latest Updated Study Guide
SECTION 1: HEALTH PROMOTION & DISEASE PREVENTION
1. A 50-year-old male presents for a routine checkup. He has no symptoms
and no significant family history. According to the USPSTF, at what age should
average-risk colorectal cancer screening begin?
A) 40 years
B) 45 years
C) 50 years
D) 55 years
E) 60 years
CORRECT ANSWER: B) 45 years
,EXPERT RATIONALE: The USPSTF updated its recommendation in 2021, lowering the
starting age for colorectal cancer screening in average-risk adults from 50 to 45 years
due to increasing incidence in younger populations.
2. A 65-year-old woman asks about osteoporosis screening. Which of the
following is the most appropriate recommendation by the USPSTF?
A) Screen all women starting at age 60
B) Screen all women starting at age 55
C) Screen all women at age 65 and younger postmenopausal women at increased
risk
D) Screen only women with a family history of osteoporosis
E) Screen only women who have had a fracture
CORRECT ANSWER: C) Screen all women at age 65 and younger
postmenopausal women at increased risk
EXPERT RATIONALE: USPSTF recommends screening for osteoporosis with bone
measurement testing in women aged 65 and older, and in postmenopausal women
under 65 who are at increased risk as determined by a formal risk assessment tool.
3. Which vaccine is recommended for adults aged 50 years and older to
prevent herpes zoster?
A) Zostavax (live zoster vaccine)
B) Varivax (varicella vaccine)
C) Shingrix (recombinant zoster vaccine)
D) MMR vaccine
E) Pneumovax 23
CORRECT ANSWER: C) Shingrix (recombinant zoster vaccine)
,EXPERT RATIONALE: Shingrix is the preferred vaccine for prevention of herpes zoster
and its complications in adults aged 50 and older. It is given in two doses and has over
90% efficacy, superior to the older Zostavax.
4. A 35-year-old woman with no risk factors asks about cervical cancer
screening. What is the current USPSTF recommendation?
A) Pap smear every year
B) Pap smear every 2 years
C) Pap smear every 3 years, or co-testing every 5 years
D) HPV testing alone every 5 years starting at age 30
E) No screening until age 40
CORRECT ANSWER: C) Pap smear every 3 years, or co-testing every 5 years
EXPERT RATIONALE: USPSTF recommends cervical cancer screening with Pap smear
alone every 3 years for women 21–65, or with high-risk HPV testing alone every 5 years,
or co-testing (Pap + HPV) every 5 years for women 30–65.
5. A 55-year-old male with a 30-pack-year history of smoking currently
smokes. Which screening does the USPSTF recommend?
A) Chest X-ray annually
B) Sputum cytology annually
C) Low-dose CT scan of the chest annually
D) Bronchoscopy every 2 years
E) PET scan every 3 years
CORRECT ANSWER: C) Low-dose CT scan of the chest annually
, EXPERT RATIONALE: USPSTF recommends annual low-dose CT (LDCT) screening for lung
cancer in adults aged 50–80 who have a 20-pack-year smoking history and currently
smoke or have quit within the past 15 years.
6. Which of the following is the most important modifiable risk factor for
cardiovascular disease in a primary care patient?
A) Age
B) Family history
C) Hypertension
D) Gender
E) Ethnicity
CORRECT ANSWER: C) Hypertension
EXPERT RATIONALE: Hypertension is the single most important modifiable risk factor for
cardiovascular disease. It can be controlled with lifestyle modifications and
pharmacotherapy, making it a primary target in preventive care.
7. A 40-year-old male asks about abdominal aortic aneurysm (AAA) screening.
According to the USPSTF, who should be screened?
A) All males aged 40 and older
B) All females aged 65 and older who smoke
C) Males aged 65–75 who have ever smoked
D) Males and females aged 65 who have ever smoked
E) No screening is recommended
CORRECT ANSWER: C) Males aged 65–75 who have ever smoked
