Diagnostics Practice
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1. Predominant form of DNA - Correct Answer: Right-handed B
2. DNA and histone interaction is due to what type of bond? - Correct
Answer: Ionic
3. What stains to the minor groove of DNA duplex? - Correct Answer: SYBR
Green
4. What is the most abundant type of RNA? - Correct Answer: Ribosomal
RNA (rRNA)
5. What does RNA act as in a retrovirus? - Correct Answer: Genome and
mRNA
6. What increases half-life of mRNA? - Correct Answer: 5' Methyl Cap
,7. What kind of DNA is most likely to be transcriptionally active? - Correct
Answer: Euchromatin
8. What is the most common type of eukaryotic DNA? - Correct Answer:
Satellite DNA
9. What specimen has the most DNA according to molecular weight? -
Correct Answer: White Blood Cells
10.What amino acids compose histones? - Correct Answer: Lysine and
Arginine
11.Amino acid that all proteins start with: - Correct Answer: Methionine
12.What protects the DNA strand during replication? - Correct Answer:
Single-stranded binding protein
13.Leading Strand - Correct Answer: 3' to 5' template
14.Lagging Strand - Correct Answer: 5' to 3' template
15.What DNA strand is being copied in transcription? - Correct Answer:
Antisense Strand
, 16.First step after newly formed mRNA is made? - Correct Answer:
Addition of poly(A) tail
17.Every time the chromosome is copied it would become shorter if not for
what enzyme? - Correct Answer: Telomerase
18.What polymerase has repair activity? - Correct Answer: Beta/Epsilon
19.What polymerase acts on leading strand? - Correct Answer: Delta
20.What polymerase acts on lagging strand? - Correct Answer: Alpha
21.Which polymerase is used for mitochondrial replication and repair? -
Correct Answer: Gamma
22.What polymerase binds the 5' end to 3' end of dsDNA? - Correct
Answer: Topoisomerase
23.Which RNA polymerase is mainly for transcription? - Correct Answer:
RNA Pol II
24.Which polymerase is involved with mRNA synthesis? - Correct Answer:
RNA Pol II