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HESI RN Exit Exam V2 2026 – Full-Length Practice Test Bank with Verified Questions & Answers, Detailed Rationales & NGN-Aligned Comprehensive Nursing Study Guide

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This 2026 HESI RN Exit Exam V2 comprehensive study guide is a complete preparation resource designed for nursing students preparing for their final exit exam. It includes a full-length practice test, verified questions and answers, and detailed rationales that enhance clinical reasoning, critical thinking, and test performance. Aligned with Next Generation NCLEX (NGN) standards, it covers essential nursing domains including medical-surgical nursing, pharmacology, pediatrics, maternity, and mental health nursing. Ideal for structured revision, remediation, and final exam readiness, this guide supports improved accuracy, confidence, and exam success.

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HESI RN Exit Exam V2 2026 – Full Practice Test, Verified
Questions & Answers, Rationales & Comprehensive Study Guide


The nurse assumes care of a postoperative adult client with type 2 diabetes mellitus
and learns that the client has a current blood glucose level of 720 mg/dL. When
assessing the client, what is the priority?
A. Assess for signs of fluid volume deficit
B. Observe wound drainage characteristics
C. Measure the level of acute pain
D. Determine when the client last ate - CORRECT ANSWER -A. Assess for signs of
fluid volume deficit


A male client tells the nurse that he is concerned that he may have a stomach ulcer,
because he is experiencing heartburn and dull gnawing pain that is relieved when
he eats. Which is the best response by the nurse?
A. Encourage the client to obtain a complete physical exam, since these symptoms
are consistent with an ulcer
B. Assure the client that his symptoms may only reflect reflux, since ulcer pain is not
relieved with food
C. Instruct the client that these mild symptoms can generally be controlled with
changes in his diet
D. Advise the client that he needs to seek immediate medical evaluation and
treatment of these symptoms - CORRECT ANSWER -A. Encourage the client to
obtain a complete physical exam, since these symptoms are consistent with an ulcer


A male client with stomach cancer returns to the unit following a total gastrectomy.
He has a nasogastric tube to suction and is receiving Lactated Ringer's solution at
75 mL/hr IV. One hour after admission to the unit, the nurse notes 300mL of blood
in the suction canister, the client's heart rate is 155 beats/minute, and his blood

,pressure is 78/48 mmHg. In addition to reporting the findings to the surgeon, which
action should the nurse implement first?
A. Measure and document the client's urinary output
B. Request the client's reserved unit of packed red blood cells
C. Prepare for placement of a central venous catheter
D. Increase the infusion rate of Lactated Ringer's solution - CORRECT ANSWER -D.
Increase the infusion rate of Lactated Ringer's solution


A heparin infusion is prescribed for a client who weighs 220 pounds. After
administering a bolus dose of 80 units/kg, the nurse calculates the infusion rate for
the heparin solution as 18 units/kg/hour. The available solution is Heparin Sodium
25,000 Units in 5% Dextrose Injection 250 mL. The nurse should program the
infusion pump to deliver how many mL/hour? - CORRECT ANSWER --1st: calculate
the weight = 220/2.2= 100kg
-Then calculate total dose in units = 18units x 100kg = 1800 units/hr
- 25000 units - in 250
1800 units ---in X ml
x = 1800 x 250/25000 =18 mL/hr


An adult male who fell 20 feet from the roof of his home has multiple injuries,
including a right pneumothorax. Chest tubes were inserted in the emergency
department prior to his transfer to the intensive care unit (ICU). The nurse notes that
the suction control chamber is bubbling at the -10cm H2O mark, which fluctuation in
the water seal, and over the past hour 75 mL of bright red blood is measured in the
collection chamber. Which intervention should the nurse implement?
A. Add sterile water to the suction control chamber
B. Give blood from the collection chamber as autotransfusion
C. Manipulate blood in tubing to drain into chamber

,D. Increase wall suction to eliminate fluctuation in water seal - CORRECT ANSWER -
A. Add sterile water to the suction control chamber


An adult male was diagnosed with stage IV lung cancer three weeks ago. His wife
approaches the nurse and asks how she will know that her husband's death is
imminent because their two adult children want to be there when he dies. Which is
the best response by the nurse?
A. Gather information regarding how long it will take for the children to arrive
B. Explain that the client will start to lose consciousness and the body systems will
slow down
C. Reassure the spouse that the healthcare provider will notify when to call the
children
D. Offer to discuss the client's health status with each of the adult children -
CORRECT ANSWER -B. Explain that the client will start to lose consciousness and the
body systems will slow down


The charge nurse of a critical care unit is informed at the beginning of the shift that
less than the optimal number of registered nurses will be working that shift. In
planning assignments, which client should receive the most care hours by a
registered nurse (RN)?
A. A 48-year-old marathon runner with a central venous catheter who is
experiencing nausea and vomiting due to electrolyte disturbance following a race
B. A 34-year-old admitted today after an emergency appendectomy who has a
peripheral intravenous catheter and a Foley catheter
C. A 63-year-old chain smoker admitted with chronic bronchitis who is receiving
oxygen via nasal cannula and has a saline-locked peripheral intravenous catheter
D. An 82-year-old client with Alzheimer's disease and a newly-fractured femur who
has a Foley catheter and soft wrist restraints applied - CORRECT ANSWER -D. An
82-year-old client with Alzheimer's disease and a newly-fractured femur who has a
Foley catheter and soft wrist restraints applied

, The nurse is preparing a dose of 60 mcg of teriparatide. The medication is labeled
"750 mcg/2.4mL". How many mL should the nurse administer? Round to nearest
tenth. - CORRECT ANSWER -0.2 mL


In caring for a client with Cushing's Syndrome, which serum laboratory value is most
important for the nurse to monitor?
A. Creatinine
B. Lactate
C. Glucose
D. Hemoglobin - CORRECT ANSWER -C. Glucose


A client who received hemodialysis yesterday is experiencing a blood pressure of
200/100 mmHg, heart rate 110 beats/minute, and respiratory rate 36
breaths/minute. The client is manifesting shortness of breath, bilateral 2+ pedal
edema, and an oxygen saturation on room air of 89%. Which action should the
nurse take first?
A. Elevate the foot of the bed
B. Restrict the client's fluids
C. Begin supplemental oxygen
D. Prepare client for hemodialysis - CORRECT ANSWER -C. Begin supplemental
oxygen


When caring for a client with full thickness burns to both lower extremities, which
assessment findings warrant immediate intervention? Select all that apply
A. Sloughing tissue around wound edges
B. Complaint of increased pain and pressure
C. Change in the quality of the peripheral pulses

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