EXAM QUESTIONS AND
VERIFIED CORRECT
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Treatment for FPHL - CORRECT ANSWER-Minoxidil, spironolactone, finasteride, estrogen
therapy
Late reporoductive years -3b and -3a. What happens with menstrual cycles, FSH, AMH, AFC,
inhibin? - CORRECT ANSWER--3b: menstrual cycles normal, FSH normal, AMH low, AFC low,
inhibin low.
-3a: subtle menstrual changes, variable FSH, AMH low, AFC low, inhibin low.
When it is appropriate to check an FSH during the cycle if you check it? and why? - CORRECT
ANSWER-Cycle day #3. Elevated estradiol can suppress FSH giving a falsely normal FSH level.
AMH
,produced by...
used to test...
Is it a screening tool for fertility?
When does it peak? - CORRECT ANSWER-produced by granulosa cells
used to test damage to ovarian follicle reserve. If AMH is low, the woman has a low ovarian
reserve.
not recommended as a screening tool to predict fertility.
Peaks at around 25 years old. So before age 25, this test is not helpful.
It is influenced by exogenous hormones. Lower in hormonal contraception users, but increases
after d/cing.
AFC - CORRECT ANSWER-Antral follicle count
Number of follicles that are detectable with ultrasound.
They are sensitive to FSH and considered to represent the availability poo of follicles.
Late menopause transition (-1) FSH level on random draw - CORRECT ANSWER-25 or higher
Black women have higher or lower FSH levels? - CORRECT ANSWER-Higher
Chinese and Japanese women have higher or lower estradiol levels compared to white, black
and hispanic women? - CORRECT ANSWER-lower
, Menopause transition-changes in SHBG and testosterone? ratio? - CORRECT ANSWER-SHBG
decreases
Testosterone/SHBG ratio increases by 80%.
Testosterone/SHGB ratio is called what? - CORRECT ANSWER-The free androgen index
What stage are VMS more likely? - CORRECT ANSWER-+1b (generally last 2 years)
What hormone is generally higher in obese women? - CORRECT ANSWER-Estrone-via
aromatization.
The postmenopausal ovary continues to produce what two hormones? - CORRECT ANSWER-
testosterone and androstenedione
Surgical menopause causes women to have lower levels of what hormone? - CORRECT
ANSWER-testosterone. 40-50% lower than in women w/ intact ovaries.
Driving piece of menopause is ovarian follicles depleting. What does this do to the inhibin B and
AMH? - CORRECT ANSWER-inhibin and AMH decrease
therefore, follicle growth is not restrained, this allows for the growth of the remaining,
diminished follicle pool.
In the menopause transition, women spend more time in what phase? - CORRECT ANSWER-
Luteal-more PMS symptoms, more frequent menstrual periods.
HPO axis theory and the menopause transition - CORRECT ANSWER-It is felt that the HPO axis
may become less sensitive to estrogen, so even with good follicle growth and estradiol
secretion, LH surges can fail which can lead to more cycle irregularity.