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NR511 Final Exam Differential Diagnosis & Primary Care Practicum (2025/2026) | 300 Verified Q&A with Rationales

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Prepare for the NR511 Final with this comprehensive 300-question exam script, fully updated for the December 2025 and 2026 proctored cycles. This guide masters the essentials of primary care differential diagnosis, covering high-yield clinical scenarios, pharmacological interventions, and ICD-10 coding logic. Designed for students aiming for an A+, it includes detailed expert rationales to help you navigate complex Examplify questions and secure your pass in the Primary Care Practicum.

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NR511 Final Exam (2026) | 300 Verified Q&A with Rationales | Chamberlain
Primary Care Practicum


Crush your NR511 Final with this comprehensive 200-question guide featuring verified
answers and clinical rationales updated for the December 2025 cycle. This review
masters high-yield primary care topics, including differential diagnoses for acute and
chronic conditions, pharmacological management, and evidence-based screening
guidelines. Designed for Examplify success, it provides the essential diagnostic pearls
and ICD-10/CPT coding logic needed to secure an A+ and move forward in your FNP
journey.




1. A 45-year-old male presents with sudden, intense pain in his right eye,
accompanied by blurred vision and "halos" around lights. Physical exam reveals a
mid-dilated, non-reactive pupil and a cloudy cornea. What is the immediate
priority?
A) Prescribe topical antibiotic drops and reassess in 48 hours.
B) Administer artificial tears and refer to optometry next week.
C) Immediate emergency referral for suspected Acute Angle-Closure Glaucoma.
D) Prescribe oral valacyclovir for suspected Herpes Zoster.
Answer: C
2. Which finding on a funduscopic exam is considered a "hallmark" of chronic,
uncontrolled Hypertension?
A) Neovascularization
B) AV Nicking and Silver Wiring
C) Cotton Wool Spots
D) Drusen
Answer: B
3. A patient presents with "painless" hearing loss. The Weber test lateralizes to
the "good" ear, and the Rinne test shows Air Conduction > Bone Conduction (AC
> BC) in both ears. This suggests:
A) Conductive hearing loss in the affected ear.
B) Sensorineural hearing loss in the affected ear.

,C) Normal hearing.
D) Cerumen impaction.
Answer: B
4. What is the first-line treatment for an adult with Acute Bacterial Rhinosinusitis
who has a confirmed Type 1 (Anaphylactic) allergy to Penicillin?
A) Amoxicillin-Clavulanate (Augmentin)
B) Doxycycline or a Respiratory Fluoroquinolone (e.g., Levofloxacin)
C) Cephalexin (Keflex)
D) Azithromycin (Z-Pak)
Answer: B
5. A 20-year-old student presents with a severe sore throat, significant fatigue,
and posterior cervical lymphadenopathy. A Rapid Strep test is negative. What is
the next most appropriate diagnostic step?
A) Throat Culture
B) Monospot (Heterophile antibody test)
C) CBC with differential (looking for atypical lymphocytes)
D) Both B and C
Answer: D
6. Which murmur is described as a "harsh, systolic crescendo-decrescendo"
heard best at the 2nd Right Intercostal Space, radiating to the carotids?
A) Mitral Regurgitation
B) Aortic Stenosis
C) Mitral Stenosis
) Aortic Regurgitation
Answer: B
7. A 62-year-old male smoker presents with "painless gross hematuria." What is
the absolute priority differential to rule out?
A) Nephrolithiasis
B) Bladder Cancer
C) Prostatitis
D) Benign Prostatic Hyperplasia (BPH)
Answer: B
8. According to JNC-8 guidelines, which is the preferred initial antihypertensive
for a 50-year-old African American male with no history of CKD?
A) Lisinopril (ACEI)

,B) Losartan (ARB)
C) Amlodipine (CCB) or Chlorthalidone (Thiazide)
D) Metoprolol (Beta-blocker)
Answer: C
9. A patient with asthma is using her Albuterol (SABA) rescue inhaler 5 times per
week. According to GINA guidelines, her asthma is classified as:
A) Well-controlled
B) Intermittent
C) Poorly controlled/Persistent
D) Normal
Answer: C
10. A "target" lesion (Erythema Migrans) is observed on a patient's leg after a
camping trip in New York. What is the treatment of choice?
A) Amoxicillin for 7 days
B) Doxycycline 100mg BID for 10–14 days
C) Ceftriaxone 250mg IM once
D) Topical Hydrocortisone
Answer: B
11. A "Positive Phalen’s maneuver" produces paresthesia in the thumb and first
two fingers. This indicates:
A) Ulnar nerve entrapment
B) Median nerve compression (Carpal Tunnel)
C) Radial nerve injury
D) Rotator cuff tear
Answer: B
12. A 22-year-old female presents with a malodorous "fishy" vaginal discharge. A
Wet Mount shows "Clue Cells" and a positive Whiff test. Diagnosis?
A) Trichomoniasis
B) Candidiasis
C) Bacterial Vaginosis (BV)
D) Chlamydia
Answer: C
13. What T-score on a DEXA scan is required for a formal diagnosis of
Osteoporosis?
A) -1.0 to -2.5

, B) > -1.0
C)


-2.5
D)


-3.5
Answer: C
14. A patient presents with "sudden, sharp" RUQ pain that causes them to catch
their breath during deep palpation of the gallbladder. This is a positive:
A) Rovsing’s Sign
B) McBurney’s Sign
C) Murphy’s Sign
D) Psoas Sign
Answer: C
15. "Bouchard’s Nodes" are bony enlargements found in which joints?
A) Distal Interphalangeal (DIP)
B) Proximal Interphalangeal (PIP)
C) Metacarpophalangeal (MCP)
D) Wrist
Answer: B
16. Which SSRI is often avoided in elderly patients due to its very long half-life
and risk of prolonged side effects?
A) Sertraline (Zoloft)
B) Escitalopram (Lexapro)
C) Fluoxetine (Prozac)
D) Paroxetine (Paxil)
Answer: C
17. A patient with chronic COPD presents with "clubbing" of the fingernails. This
is an anatomical response to:
A) Acute bacterial infection
B) Chronic hypoxia
C) Heavy tobacco use only
D) Right-sided heart failure
Answer: B

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