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Highlights on STEMI Management - emergency medicine lecture, ESC Guidelines (2017) concise review note

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This document summarizes the key concepts in the diagnosis and management of ST-elevation myocardial infarction (STEMI) based on ESC guidelines. It covers ECG localization of infarcts, differentiation between myocardial injury and infarction, and critical management principles including reperfusion strategies and contraindications to thrombolysis. The notes also include important clinical patterns such as right ventricular infarction, posterior MI, and complications like arrhythmias and tamponade. It is useful for rapid revision and exam preparation in emergency and cardiology settings.

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Highlights on STEMI
Management
Based on 2017 ESC Guidelines (is there is a more recent guidelines?)


Types of STEMI

Lateral or high lateral STEMI → V1 and aVL

Extensive anterior STEMI → V1 - V6

Antero-septal STEMI → V1 - V4 ( V1 - V2 → septal, V3 - V4 → anterior wall)

Lateral STEMI → V5 - V6

Posterior STEMI → V7 - V9

Inferior STEMI (II, III, aVF)



Universal definition of MI
Myocardial injury: evidence of elevated cTn with at least one value >99th
percentile upper reference limit (URL). The myocardial injury is considered
acute if there is a rise and or fall of cTN values.

Acute myocardial injury: is injury with rise and/or fall of cTn values
(dynamic), if the values were static (no fall or rise) → chronic injury

Difference between acute myocardial infarction
and acute myocardial injury
Acute myocardial infarction is an acute myocardial injury with at least one of the
following:

Symptoms of myocardial ischemia

New ischemic ECG changes

Development of pathological Q-waves

Imaging of evidence of new loss of viable myocardium or new regional wall
motion abnormality in a pattern consistent with ischemic etiology



Highlights on STEMI Management 1

, Identification of a coronary thrombus by angiography or autopsy

⚡Both anterior and inferior STEMIs could result in LV dysfunction
Difference between stuttering and recurrent course STEMI
Recurrent: new episode of ischemia after a symptom-free interval, with the
following key features

Pain completely resolves, then returns later

There is a clear gap between episodes

Each episode is separate


⚡ Recurrent dynamic (more specific)
Recurrent symptoms + changing ECG each time

Example:

ST elevation → resolves

Then ST depression or T inversion



Stuttering: intermittent, repeated episodes of ischemia without full
resolution, with the following key features:

Pain comes and goes frequently

Incomplete relief between episodes

Often ongoing instability (plaque rupture with intermittent occlusion)


Reciprocal ST depression (ECG)
A ST segment depression seen in leads opposite to the area of ST elevation
during a myocardial infarction

ST-Elevation Myocardial Infarction:

Inferior STEMI (II, III, aVF)
→ Reciprocal depression in I and aVL




Highlights on STEMI Management 2

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Uploaded on
April 24, 2026
Number of pages
14
Written in
2025/2026
Type
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Emad magdy shawky
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