FULL TEST BANK CLAYTON’S BASIC PHARMACOLOGY FOR NURSES 20TH EDITION BY MICHELLE J. WILLIHNGANZ MS RN CNE (AUTHOR) GRADED A+

,Chapter 1: Drug Definitions, Standards, and Information Sources
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Test Bank
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MULTIPLE CHOICE a2




1. What is the name under which a drug is listed by the U.S. Food and Drug Administration
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(FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: a 2 C
The official name is the name under which a drug is listed by the FDA. The brand name, or
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trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
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name is provided by the U.S. Adopted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: a2 a2 a 2 a2




a 2 TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
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2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database a2 a2 a2




c. United States Pharmacopoeia/National Formulary (USP NF) a2 a2 a2 a2 a2




d. Drug Interaction Facts a2 a2




ANS: a 2 C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains evidence based
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information on herbal medicines and herbal combination products; it does not include
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information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional
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supplements.
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DIF: Cognitive Level: Knowledge REF: p. 2 a2 a2 a 2 a2 OBJ:
a 4 TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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3. What is the most comprehensive reference available to research a drug interaction?
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a. Drug Facts and Comparisons a2 a2 a2




b. Drug Interaction Facts a2 a2




c. Handbook on Injectable Drugs a2 a2 a2




d. Martindale—The Complete Drug Reference a2 a2 a2




ANS: a 2 B

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Material
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First published in 1983, Drug Interaction Facts is the most comprehensive book available on
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drug interactions. In addition to monographs listing various aspects of drug interactions, this
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information is reviewed and updated by an internationally renowned group of physicians and
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pharmacists with clinical and scientific expertise.
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DIF: Cognitive Level: Comprehension REF: p. 3 a2 a2 a 2 a2 OBJ:
a 3 TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section
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of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug?
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a. Manufacturer’s section a2




b. Brand and Generic Name section a2 a2 a2 a2




c. Product Category section a2 a2




d. Product Information section a2 a2




ANS: a 2 B
A physician’s order would include the brand and/or generic name of the drug. The alphabetic
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index in the PDR would make this section the most user friendly. Based on a physician’s order,
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manufacturer’s information and classification information would not be known. The
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Manufacturer’s section is a roster of manufacturers. The Product Category section lists
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products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and
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antibiotics. The Product Information section contains reprints of the package inserts for the
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major products of manufacturers.
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DIF: Cognitive Level: Comprehension REF: p. 3 a2 a2 a 2 a2 OBJ:
a 4 TOP: Nursing Process Step: Planning
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MSC: NCLEX Client Needs Category: Physiological Integrity
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5. Which online drug reference makes available to health care providers and the public a
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standard, comprehensive, up to date look up and downloadable resource about medicines?
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a. American Drug Index a2 a2




b. American Hospital Formulary a2 a2




c. DailyMed
d. Physicians’ Desk Reference (PDR) a2 a2 a2




ANS: a 2 C
DailyMed makes available to health care providers and the public a standard, comprehensive, up
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to date look up and downloadable resource about medicines. The American Drug Index is not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient
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use. The PDR is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 4 a2 a2 a 2 a2 OBJ:
a 5 TOP: Nursing Process Step: Implementation
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MSC: NCLEX Client Needs Category: Physiological Integrity
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) a2 a2 a2 a2 a2 a2




b. Durham Humphrey Amendment (1952) a2 a2 a2




c. Controlled Substances Act (1970) a2 a2 a2




19TH EDITION
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d. Kefauver Harris Drug Amendment (1962) a2 a2 a2 a2




ANS: a 2 A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
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of all drugs before marketing. Later amendments and acts helped tighten FDA control and
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ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot
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be used safely without medical supervision and restricts their sale to prescription by a licensed
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practitioner. The Controlled Substances Act addresses only controlled substances and their
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categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
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safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
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before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 4 a2 a2 a 2 a2 OBJ:
a 8 TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
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a2 dependency. Under which classification does this drug fall? a2 a2 a2 a2 a2 a2 a2




a. I
b. II
c. III
d. IV
ANS: a 2 B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severe psychological and physical dependence. Schedule I drugs have high potential for abuse
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and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
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to low to moderate physical dependence or high psychological dependence. Schedule IV drugs
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have low potential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: a2 a2 a 2 a2 a2 a2 a2




a 7 TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
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8. What would the FDA do to expedite drug development and approval for an outbreak of
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a2 smallpox, for which there is no known treatment? a2 a2 a2 a2 a2 a2 a2




a. List smallpox as a health orphan disease. a2 a2 a2 a2 a2 a2




b. Omit the preclinical research phase. a2 a2 a2 a2




c. Extend the clinical research phase. a2 a2 a2 a2




d. Fast track the investigational drug. a2 a2 a2 a2




ANS: a 2 D
Once the Investigational New Drug Application has been approved, the drug can receive
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highest priority within the agency, which is called fast tracking. A smallpox outbreak would
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become a priority concern in the world. Orphan diseases are not researched in a priority
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manner. Preclinical research is not omitted. Extending any phase of the research would mean a
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longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
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clinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge REF: a2 a2 a 2 p. 7 a2 OBJ:
a 8 TOP: Nursing Process Step: Assessment
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19TH EDITION
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