PMHNP PHARMACOLOGY EXAM
COMPLETE QUESTIONS AND CORRECT
ANSWERS NEW EXAM UPDATE TESTED
AND APPROVED!!!
What is the role of the dopamine? - CORRECT ANSWER ✔✔-it's an
excitatory neurotransmitter important in controlling thoughts and emotions, and
for the cortex, meso- cortical track and are involved in attention focus and
depression
-dopamine also helps control complex movement in the nigrostriatal dopamine
pathway
-in the mesolimbic dopamine pathway that projects to the nucleus accumbens, a
part of limbic system involved with pleasurable behaviors; elevated dopamine
levels in this pathway or associate it with psychosis -influences the
tuberoinfundibulnar pathway that influences prolactin excretions- blockade in
this pathway increase gynecomastia and prolactin - D2 receptor is stimulated
by dopaminergic agonist for Parkinson's treatment and blocked by dopamine
antagonist such as antipsychotics
What is the role of norepinephrine? - CORRECT ANSWER ✔✔- located
primarily int he locus coeruleus (in brainstem)
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,- projections from LC to frontal cortex regulate mood (beta 1 receptors) -
frontal cortex projections influence attention, concentration, (alpha 2 receptors)
- projections in to the limbic cortex influence emotions and energy - brain
stem projections affect blood pressure and innervate the heart via beta 1
receptors
- innervation of the urinary treat via the sympathetic neurons effects
bladder emptying, causing urinary retentions via alpha one receptors
- excitatory NT that helps elevate mood, modulate attention, and fatigue
- may contribute to anxiety d/o
What is the role of 5HT? - CORRECT ANSWER ✔✔-5HT1A
(somatodendritic) and 5HT1 D( terminal autoreceptor) are presynaptic
- located primarily in the raphe nucleus
- Projects from raphe nucleus to: frontal lobe, basal ganglia (esp 5HT2A
which control movements/obsessions/compulsions), limbic area, (esp
5HT2A and 5HT2C, related to anxiety and panic), hypothalamus (5HT3- reg
appetite and sleep), brainstem, spinal cord, peripheral (5HT3 and 4.) regulate
appetite and GI motility.
What is the role of 5HT 2A? - CORRECT ANSWER ✔✔in basal ganglia
5HT2A controls movements/obsessions/compulsion
limbic system - related to anxiety and panic
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, What is the role of 5HT2C ? - CORRECT ANSWER ✔✔in limbic system,
related to anxiety and panic
What is the role of 5HT3? - CORRECT ANSWER ✔✔Regulate appetite
and
sleep in hypothalamus
in gut, with 5HT4, helps regulate appetite and GI motility
What is the role of GABA? - CORRECT ANSWER ✔✔inhibitory NT -
works
to sedate and calm
What is the role of acetylcholine? - CORRECT ANSWER ✔✔Plays a role
in
cognition and memory
Held imbalance with dopamine in the substantia nigra
What is the role of glutamate? - CORRECT ANSWER ✔✔It is an
excitatory
neurotransmitter
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COMPLETE QUESTIONS AND CORRECT
ANSWERS NEW EXAM UPDATE TESTED
AND APPROVED!!!
What is the role of the dopamine? - CORRECT ANSWER ✔✔-it's an
excitatory neurotransmitter important in controlling thoughts and emotions, and
for the cortex, meso- cortical track and are involved in attention focus and
depression
-dopamine also helps control complex movement in the nigrostriatal dopamine
pathway
-in the mesolimbic dopamine pathway that projects to the nucleus accumbens, a
part of limbic system involved with pleasurable behaviors; elevated dopamine
levels in this pathway or associate it with psychosis -influences the
tuberoinfundibulnar pathway that influences prolactin excretions- blockade in
this pathway increase gynecomastia and prolactin - D2 receptor is stimulated
by dopaminergic agonist for Parkinson's treatment and blocked by dopamine
antagonist such as antipsychotics
What is the role of norepinephrine? - CORRECT ANSWER ✔✔- located
primarily int he locus coeruleus (in brainstem)
Page 1 of 21
,- projections from LC to frontal cortex regulate mood (beta 1 receptors) -
frontal cortex projections influence attention, concentration, (alpha 2 receptors)
- projections in to the limbic cortex influence emotions and energy - brain
stem projections affect blood pressure and innervate the heart via beta 1
receptors
- innervation of the urinary treat via the sympathetic neurons effects
bladder emptying, causing urinary retentions via alpha one receptors
- excitatory NT that helps elevate mood, modulate attention, and fatigue
- may contribute to anxiety d/o
What is the role of 5HT? - CORRECT ANSWER ✔✔-5HT1A
(somatodendritic) and 5HT1 D( terminal autoreceptor) are presynaptic
- located primarily in the raphe nucleus
- Projects from raphe nucleus to: frontal lobe, basal ganglia (esp 5HT2A
which control movements/obsessions/compulsions), limbic area, (esp
5HT2A and 5HT2C, related to anxiety and panic), hypothalamus (5HT3- reg
appetite and sleep), brainstem, spinal cord, peripheral (5HT3 and 4.) regulate
appetite and GI motility.
What is the role of 5HT 2A? - CORRECT ANSWER ✔✔in basal ganglia
5HT2A controls movements/obsessions/compulsion
limbic system - related to anxiety and panic
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, What is the role of 5HT2C ? - CORRECT ANSWER ✔✔in limbic system,
related to anxiety and panic
What is the role of 5HT3? - CORRECT ANSWER ✔✔Regulate appetite
and
sleep in hypothalamus
in gut, with 5HT4, helps regulate appetite and GI motility
What is the role of GABA? - CORRECT ANSWER ✔✔inhibitory NT -
works
to sedate and calm
What is the role of acetylcholine? - CORRECT ANSWER ✔✔Plays a role
in
cognition and memory
Held imbalance with dopamine in the substantia nigra
What is the role of glutamate? - CORRECT ANSWER ✔✔It is an
excitatory
neurotransmitter
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