PATIENT SAFETY AND QUALITY NCLEX QUESTIONS
2026/2027 | 60 NCLEX-Style Questions with Verified Answers
| QSEN & NCSBN Aligned | Summer Edition | Pass
Guaranteed - A+ Graded
Part One: Infection Control & Prevention (Standard/Transmission-Based Precautions) (Questions 1–15)
Q1: A nurse is caring for a patient with confirmed Clostridioides difficile (C. diff)
infection. Which PPE is required before entering the room?
A. Gloves and surgical mask only
B. Gown and gloves
C. N95 respirator, gown, and gloves
D. Face shield and sterile gloves
B. Gown and gloves [CORRECT]
D. Face shield and sterile gloves
Correct Answer: B
Rationale: C. diff requires Contact Precautions—gown and gloves. A surgical mask (A) is
for droplet; N95 (C) is for airborne; face shield and sterile gloves (D) are unnecessary
and incorrect for standard C. diff precautions.
Q2: A nurse is preparing to insert a Foley catheter. Which hand hygiene method is most
appropriate before the procedure?
A. Alcohol-based hand rub for 15 seconds
B. Soap and water handwashing for at least 20 seconds
C. Wearing gloves alone is sufficient; no hand hygiene needed
D. Alcohol-based hand rub for 5 seconds
B. Soap and water handwashing for at least 20 seconds [CORRECT]
D. Alcohol-based hand rub for 5 seconds
Correct Answer: B
Rationale: Invasive procedures like catheter insertion require soap and water
handwashing for at least 20 seconds. Alcohol rub (A) is acceptable for standard care
,but soap and water is preferred before invasive procedures. Gloves alone (C) are never
enough; 5 seconds (D) is inadequate.
Q3: A patient is admitted with active pulmonary tuberculosis. The nurse should place
the patient in which type of isolation?
A. Contact Precautions
B. Droplet Precautions
C. Airborne Precautions
D. Protective Isolation
C. Airborne Precautions [CORRECT]
D. Protective Isolation
Correct Answer: C
Rationale: TB spreads via airborne droplet nuclei, requiring Airborne Precautions with a
negative-pressure room and N95 respirator. Contact (A) is for direct contact diseases;
Droplet (B) is for larger respiratory droplets; Protective Isolation (D) is for
immunocompromised patients.
Q4: A nurse enters a patient's room wearing gloves after changing a wound dressing.
Before leaving the room, what is the correct sequence?
A. Remove gloves, perform hand hygiene, then leave
B. Leave the room first, then remove gloves at the nurses' station
C. Remove gloves and leave; hand hygiene can wait until after documentation
D. Wipe gloves with alcohol-based hand rub and reuse them for the next patient
A. Remove gloves, perform hand hygiene, then leave [CORRECT]
D. Wipe gloves with alcohol-based hand rub and reuse them for the next patient
Correct Answer: A
Rationale: Gloves must be removed and hand hygiene performed before leaving the
room to prevent pathogen spread. Leaving with gloves on (B), delaying hygiene (C), or
reusing gloves (D) are all serious infection control violations.
Q5: A patient is on neutropenic precautions. Which visitor restriction is most
appropriate?
A. Allow all visitors as long as they wear a surgical mask
, B. Restrict visitors with active infections, recent live vaccine, or fresh flowers and plants
C. No visitors are allowed under any circumstances
D. Visitors may enter without any restrictions since neutropenia is not contagious
B. Restrict visitors with active infections, recent live vaccine, or fresh flowers and plants
[CORRECT]
D. Visitors may enter without any restrictions since neutropenia is not contagious
Correct Answer: B
Rationale: Neutropenic precautions protect the immunocompromised patient from
infection. Restricting sick visitors, live vaccine recipients, and plants/flowers reduces
pathogen exposure. Complete ban (C) is unnecessary; no restrictions (D) is dangerous.
Q6: A nurse is performing sterile dressing change on a central line site. A sterile glove
touches the patient's unsterile bed rail. What is the nurse's best action?
A. Continue the procedure since the bed rail is clean
B. Change the contaminated glove and continue with a new sterile glove
C. Switch to clean gloves and finish the dressing change
D. Apply alcohol to the glove and continue
B. Change the contaminated glove and continue with a new sterile glove [CORRECT]
D. Apply alcohol to the glove and continue
Correct Answer: B
Rationale: Sterile technique requires that anything touching a non-sterile surface is
contaminated. The nurse must change the glove. Continuing (A), switching to clean
gloves (C), or attempting to sterilize the glove (D) all break sterile technique.
Q7: A patient is diagnosed with influenza. Which isolation precautions should the nurse
implement?
A. Contact Precautions
B. Droplet Precautions
C. Airborne Precautions
D. Standard Precautions only
B. Droplet Precautions [CORRECT]
D. Standard Precautions only
Correct Answer: B
2026/2027 | 60 NCLEX-Style Questions with Verified Answers
| QSEN & NCSBN Aligned | Summer Edition | Pass
Guaranteed - A+ Graded
Part One: Infection Control & Prevention (Standard/Transmission-Based Precautions) (Questions 1–15)
Q1: A nurse is caring for a patient with confirmed Clostridioides difficile (C. diff)
infection. Which PPE is required before entering the room?
A. Gloves and surgical mask only
B. Gown and gloves
C. N95 respirator, gown, and gloves
D. Face shield and sterile gloves
B. Gown and gloves [CORRECT]
D. Face shield and sterile gloves
Correct Answer: B
Rationale: C. diff requires Contact Precautions—gown and gloves. A surgical mask (A) is
for droplet; N95 (C) is for airborne; face shield and sterile gloves (D) are unnecessary
and incorrect for standard C. diff precautions.
Q2: A nurse is preparing to insert a Foley catheter. Which hand hygiene method is most
appropriate before the procedure?
A. Alcohol-based hand rub for 15 seconds
B. Soap and water handwashing for at least 20 seconds
C. Wearing gloves alone is sufficient; no hand hygiene needed
D. Alcohol-based hand rub for 5 seconds
B. Soap and water handwashing for at least 20 seconds [CORRECT]
D. Alcohol-based hand rub for 5 seconds
Correct Answer: B
Rationale: Invasive procedures like catheter insertion require soap and water
handwashing for at least 20 seconds. Alcohol rub (A) is acceptable for standard care
,but soap and water is preferred before invasive procedures. Gloves alone (C) are never
enough; 5 seconds (D) is inadequate.
Q3: A patient is admitted with active pulmonary tuberculosis. The nurse should place
the patient in which type of isolation?
A. Contact Precautions
B. Droplet Precautions
C. Airborne Precautions
D. Protective Isolation
C. Airborne Precautions [CORRECT]
D. Protective Isolation
Correct Answer: C
Rationale: TB spreads via airborne droplet nuclei, requiring Airborne Precautions with a
negative-pressure room and N95 respirator. Contact (A) is for direct contact diseases;
Droplet (B) is for larger respiratory droplets; Protective Isolation (D) is for
immunocompromised patients.
Q4: A nurse enters a patient's room wearing gloves after changing a wound dressing.
Before leaving the room, what is the correct sequence?
A. Remove gloves, perform hand hygiene, then leave
B. Leave the room first, then remove gloves at the nurses' station
C. Remove gloves and leave; hand hygiene can wait until after documentation
D. Wipe gloves with alcohol-based hand rub and reuse them for the next patient
A. Remove gloves, perform hand hygiene, then leave [CORRECT]
D. Wipe gloves with alcohol-based hand rub and reuse them for the next patient
Correct Answer: A
Rationale: Gloves must be removed and hand hygiene performed before leaving the
room to prevent pathogen spread. Leaving with gloves on (B), delaying hygiene (C), or
reusing gloves (D) are all serious infection control violations.
Q5: A patient is on neutropenic precautions. Which visitor restriction is most
appropriate?
A. Allow all visitors as long as they wear a surgical mask
, B. Restrict visitors with active infections, recent live vaccine, or fresh flowers and plants
C. No visitors are allowed under any circumstances
D. Visitors may enter without any restrictions since neutropenia is not contagious
B. Restrict visitors with active infections, recent live vaccine, or fresh flowers and plants
[CORRECT]
D. Visitors may enter without any restrictions since neutropenia is not contagious
Correct Answer: B
Rationale: Neutropenic precautions protect the immunocompromised patient from
infection. Restricting sick visitors, live vaccine recipients, and plants/flowers reduces
pathogen exposure. Complete ban (C) is unnecessary; no restrictions (D) is dangerous.
Q6: A nurse is performing sterile dressing change on a central line site. A sterile glove
touches the patient's unsterile bed rail. What is the nurse's best action?
A. Continue the procedure since the bed rail is clean
B. Change the contaminated glove and continue with a new sterile glove
C. Switch to clean gloves and finish the dressing change
D. Apply alcohol to the glove and continue
B. Change the contaminated glove and continue with a new sterile glove [CORRECT]
D. Apply alcohol to the glove and continue
Correct Answer: B
Rationale: Sterile technique requires that anything touching a non-sterile surface is
contaminated. The nurse must change the glove. Continuing (A), switching to clean
gloves (C), or attempting to sterilize the glove (D) all break sterile technique.
Q7: A patient is diagnosed with influenza. Which isolation precautions should the nurse
implement?
A. Contact Precautions
B. Droplet Precautions
C. Airborne Precautions
D. Standard Precautions only
B. Droplet Precautions [CORRECT]
D. Standard Precautions only
Correct Answer: B
