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Terms in this set (65)
What percentage of the body's The brain uses 20% of the body's oxygen suppy
oxygen supply and cardiac output and 15% of the body's cardiac output.
does the brain use? *brain cells do not store oxygen or glucose. The
need a constant suppy of micronutrients from
arterial blood.
What is the normal blood flow to Normal blood flow to the brain is 50-
cerebral tissue? When does 55ml/100/min
electrical failure occur? electrical failure occurs at 15-20ml/100/min
temporal lobe hearing, memory, learning, wernicke (receptive
aphasia), visual and auditory memories, behavioral
elements
frontal lobe personality, affect, tact, inhibition, judgement,
planning, motor strip body parts, frontal eye
fields- conjugate eye movements; pupil changes,
extra pyramidal motor control, motor speech-
articulation, speed, and rhythm of speech,
creative thought,abstract thinking
,parietal lobe pain, temperature, light, touch, vibration, two
point discrimination, visual function, language,
reading, internal stimuli, tactile sensation, and
sensory comprehension
occipital lobe infarcts macular vision, broca's area (expressive aphasia),
facial neurons
Cerebellum The cerebellum first receives information about
an intended movement then it sends information
back to the motor cortex about the required
direction, force, and duration of the movement. It
acts like an air traffic controller. The cerebellum
can't initiate movement but is responsible for
unconscious coordination of movement. can
cause lack of coordination, clumsiness,
shaking/tremors
* It is important to diagnose cerebellum infarcts
early because swelling may cause brain stem
compression or hydrocephalous
Cerebrum grey matter: cognition and personality deficits
white matter (deep): regions of the brain cannot
communicate with each other
What causes brain stem infarcts? usually related to basilar occlusion. This type of
infarct is serious or fatal. Survivors may be left in a
vegatative state
What is the main cause of cell hypoxia or anoxia
death?
, What factors influence the rate and 1: rate of onset
extent of penumbral tissue and 2: Duration of ischemia
infarcted tissue 3: Degree of collateral circulation perfusing the
infarcted zone
4: functionality of systemic circulation
5: hematologic factors
6: metabolic factors
What is an appoptic cell death programed cell death in the penumbral zone:
pathway? normal biologic function where cells are
programmed to die in an organized fashion after
nearby cell death
What is a necrotic cell death loss of O2 and glucose and cellular electrolyte
pathway? exchange from a loss of atrial perfusion causes
energy failure and rapid cytoskeletal breakdown.
What is the ischemic cascade? lack of blood-infarct-edema-swelling-center of
brain shifts from midline-increased ICP-
compression of neurons, nerve tracts, and
cerebral arteries-persistant edema-irreversable
damage /death