Facilitated Diffusion
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Polar molecules diffuse across the cell membrane with the help of carrier
proteins.
- Passive, no energy
- Stuff move down their concentration gradient.
S4 wing mechanism
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, S4's natural position is up towards the outer surface of the cell membrane.
- BUT, when membrane is polarized, the S4 wing (+) charge is attracted to
the (-) charge inner surface of the cell membrane. It moves downwards,
shutting the channel.
- Depolarizing helps the S4 wing migrate back up. Opening the channel.
Secondary Active Transport
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Move molecules against their concentration gradient.
- Does not require energy.
- Does not involve ATP catabolism.
- Substrate is moved against its gradient via the kinetic energy produced by
a substance moving down its concentration gradient.
Voltage gated channels
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Changes conformations due to changes in the potential difference across
the membrane.
- Voltage sensing mechanism is mediated by the 4th transmembrane
domain, S4 wing.
Membrane Potential
Give this one a try later!
Give this one a try later!
Polar molecules diffuse across the cell membrane with the help of carrier
proteins.
- Passive, no energy
- Stuff move down their concentration gradient.
S4 wing mechanism
Give this one a try later!
, S4's natural position is up towards the outer surface of the cell membrane.
- BUT, when membrane is polarized, the S4 wing (+) charge is attracted to
the (-) charge inner surface of the cell membrane. It moves downwards,
shutting the channel.
- Depolarizing helps the S4 wing migrate back up. Opening the channel.
Secondary Active Transport
Give this one a try later!
Move molecules against their concentration gradient.
- Does not require energy.
- Does not involve ATP catabolism.
- Substrate is moved against its gradient via the kinetic energy produced by
a substance moving down its concentration gradient.
Voltage gated channels
Give this one a try later!
Changes conformations due to changes in the potential difference across
the membrane.
- Voltage sensing mechanism is mediated by the 4th transmembrane
domain, S4 wing.
Membrane Potential
Give this one a try later!
