NUR 211 Unit 5 Exam Questions and Answers With Verified Solutions
2025
meds for clotting disorders - ✔✔anticoag: apixaban, rivaroxaban
Thrombin inhib: Argatroban, fondaparinux, Bivalirudin
Hydroxyurea
CF meds - ✔✔Heliox 50/50
CFTR: Ivacaftor, Lumacasftor
Acetylcysteine
ABX: sulfa-bactrim
Aminoglycosides
Merrem
Sickle meds - ✔✔Pain Meds (opioids)
Hydroxyurea
L-glutamine (amino acid)
Crizanlizumab
Leukemia meds - ✔✔Epoetin Alfa
Acute: Induction, Consolidation, and Maintenance Chemotherapy
Chronic: CML: Imatinib mesylate
dasatinib, interferon alpha
CLL: chemo, Rituximab with cyclophosphamide, fludarabine, or bendamustine
breast cancer meds - ✔✔Neoadjuvant or Adjuvant Therapy
Radiation
Chemotherapy
Hormone Therapy
, Aromatase Inhibitors (Anastrozole, exemestane, and letrozole)
SERMs (Tamoxifen)
Targeted Therapy (for HER2-positive)
Monoclonal antibodies, Kinase inhibitors
Immunotherapy
Polycythemia vera (many cells) high altitudes bad. DIA: blood tests CBC, bone marrow biopsy, genetic
testing
can preogress to myelofibrosis or acute leukemia - ✔✔RBC > 6 mill, PTL, WBC, HGB > 17 HCT >55, uric
acid elevated
Jak2kinase gene
sym: itching, sweating, joint pain, enlarged spleen, HTN, hyperkalemia, gout sympt, poor clotting
treatmnet: phlebotomy, hydration, Anticoagulants
Aspirin
Hydroxyurea: oral chemotherapy drug*
Pegylated interferon: rbc produ
Hemophilia A B (males) DIA factor assay, genetic testing
COMPl: dev of antibodies against replacement factors, joint damage - ✔✔X-linked, factor 8 or 9, Von
willebrand disease
TM: desmopressin acetate (hemo A), DDAVP, Cyklaokapron
Thrombocytopenia - ✔✔PTL < 150,000
ITP: acute in children, immune disorder ptl destruction (chemo, OC, preeclampsia, infection lupus)
steroids 1st line TM IVIG,
TTP: ADAMTS13 def increased PTL aggregation, microthrombi. Excess VonWillian factors causes ptl to
clump and decrease in circulation, HIT: 5- 14 days after starting heparin, unexplained PTL drop by 50%,
causes microclots
Clinical manifestations ITP, TTP, HIT - ✔✔ITP: antiplatelet antibodies in blood
2025
meds for clotting disorders - ✔✔anticoag: apixaban, rivaroxaban
Thrombin inhib: Argatroban, fondaparinux, Bivalirudin
Hydroxyurea
CF meds - ✔✔Heliox 50/50
CFTR: Ivacaftor, Lumacasftor
Acetylcysteine
ABX: sulfa-bactrim
Aminoglycosides
Merrem
Sickle meds - ✔✔Pain Meds (opioids)
Hydroxyurea
L-glutamine (amino acid)
Crizanlizumab
Leukemia meds - ✔✔Epoetin Alfa
Acute: Induction, Consolidation, and Maintenance Chemotherapy
Chronic: CML: Imatinib mesylate
dasatinib, interferon alpha
CLL: chemo, Rituximab with cyclophosphamide, fludarabine, or bendamustine
breast cancer meds - ✔✔Neoadjuvant or Adjuvant Therapy
Radiation
Chemotherapy
Hormone Therapy
, Aromatase Inhibitors (Anastrozole, exemestane, and letrozole)
SERMs (Tamoxifen)
Targeted Therapy (for HER2-positive)
Monoclonal antibodies, Kinase inhibitors
Immunotherapy
Polycythemia vera (many cells) high altitudes bad. DIA: blood tests CBC, bone marrow biopsy, genetic
testing
can preogress to myelofibrosis or acute leukemia - ✔✔RBC > 6 mill, PTL, WBC, HGB > 17 HCT >55, uric
acid elevated
Jak2kinase gene
sym: itching, sweating, joint pain, enlarged spleen, HTN, hyperkalemia, gout sympt, poor clotting
treatmnet: phlebotomy, hydration, Anticoagulants
Aspirin
Hydroxyurea: oral chemotherapy drug*
Pegylated interferon: rbc produ
Hemophilia A B (males) DIA factor assay, genetic testing
COMPl: dev of antibodies against replacement factors, joint damage - ✔✔X-linked, factor 8 or 9, Von
willebrand disease
TM: desmopressin acetate (hemo A), DDAVP, Cyklaokapron
Thrombocytopenia - ✔✔PTL < 150,000
ITP: acute in children, immune disorder ptl destruction (chemo, OC, preeclampsia, infection lupus)
steroids 1st line TM IVIG,
TTP: ADAMTS13 def increased PTL aggregation, microthrombi. Excess VonWillian factors causes ptl to
clump and decrease in circulation, HIT: 5- 14 days after starting heparin, unexplained PTL drop by 50%,
causes microclots
Clinical manifestations ITP, TTP, HIT - ✔✔ITP: antiplatelet antibodies in blood
