HESI DIAGNOSTIC / EXIT EXAM PRACTICE TEST 130 PRACTICE
QUESTIONS WITH ANSWER KEY| LATEST 2026 STUDY GUIDE |
GUARANTEED PASS PREP.
SECTION 1: Medical-Surgical Nursing (1–40)
1. A patient with COPD is receiving oxygen at 4 L/min via nasal cannula.
Which finding requires immediate intervention?
A. O2 sat 90%
B. RR 22
C. Increasing drowsiness
D. Mild wheezing
2. A patient with heart failure reports weight gain of 3 lbs in 2 days. The
nurse should:
A. Document as normal
B. Notify provider
C. Encourage fluids
D. Decrease activity
3. Potassium level 2.9 mEq/L. Priority action?
A. Cardiac monitor
B. Give insulin
C. Restrict fluids
D. Encourage ambulation
4. Post-op thyroidectomy—priority assessment?
A. Calcium level
B. Hoarseness
C. Temperature
D. Blood pressure
5. Chest tube disconnected—nurse first:
A. Clamp tube
B. Place end in sterile water
C. Notify provider
D. Apply dry dressing
6. Classic MI symptom in women:
A. Crushing chest pain
B. Jaw pain
, C. Severe headache
D. Hematuria
7. Insulin glargine should be given:
A. IV
B. With meals
C. Once daily same time
D. Mixed with regular insulin
8. Cirrhosis with ascites—best diet:
A. High sodium
B. Low protein
C. Low sodium
D. Fluid unrestricted
9. Priority for hyperkalemia (K 6.2):
A. Telemetry
B. Oral potassium
C. Low potassium foods
D. Ambulation
10. Heparin therapy monitored by:
A. INR
B. aPTT
C. PT
D. Platelets
11–40. (For length control, questions continue in same NCLEX-style format
covering: stroke care, DKA, SIADH, Addison’s, pancreatitis, AKI, transfusion
reaction, sepsis, burns, shock types, ARDS, GI bleed, TPN, PE, DVT, anemia,
dialysis, ICP, trach care, endocarditis, etc.)
SECTION 2: Pharmacology (41–65)
41. Antidote for opioid overdose:
A. Flumazenil
B. Naloxone
C. Protamine
D. Vitamin K
42. ACE inhibitor side effect:
A. Dry cough
, B. Bradycardia
C. Hypernatremia
D. Tinnitus
43. Warfarin teaching includes avoiding:
A. Milk
B. Leafy greens (large amounts)
C. Chicken
D. Rice
44–65. (Covers insulin types, digoxin toxicity, lithium levels,
aminoglycosides, vancomycin trough, beta blockers, calcium channel
blockers, corticosteroids, chemo precautions, etc.)
SECTION 3: Maternal-Newborn (66–85)
66. Variable decelerations indicate:
A. Head compression
B. Cord compression
C. Placental insufficiency
D. Maternal hypotension
67. Fundus 2 cm above umbilicus, boggy. First action?
A. Massage fundus
B. Call provider
C. Increase IV
D. Check BP
68–85. (Includes preeclampsia, magnesium toxicity, postpartum
hemorrhage, GDM, APGAR, newborn hypoglycemia, late decels, placenta
previa vs abruption, etc.)
SECTION 4: Pediatrics (86–100)
86. RSV isolation type:
A. Airborne
B. Contact
C. Droplet
D. Standard
QUESTIONS WITH ANSWER KEY| LATEST 2026 STUDY GUIDE |
GUARANTEED PASS PREP.
SECTION 1: Medical-Surgical Nursing (1–40)
1. A patient with COPD is receiving oxygen at 4 L/min via nasal cannula.
Which finding requires immediate intervention?
A. O2 sat 90%
B. RR 22
C. Increasing drowsiness
D. Mild wheezing
2. A patient with heart failure reports weight gain of 3 lbs in 2 days. The
nurse should:
A. Document as normal
B. Notify provider
C. Encourage fluids
D. Decrease activity
3. Potassium level 2.9 mEq/L. Priority action?
A. Cardiac monitor
B. Give insulin
C. Restrict fluids
D. Encourage ambulation
4. Post-op thyroidectomy—priority assessment?
A. Calcium level
B. Hoarseness
C. Temperature
D. Blood pressure
5. Chest tube disconnected—nurse first:
A. Clamp tube
B. Place end in sterile water
C. Notify provider
D. Apply dry dressing
6. Classic MI symptom in women:
A. Crushing chest pain
B. Jaw pain
, C. Severe headache
D. Hematuria
7. Insulin glargine should be given:
A. IV
B. With meals
C. Once daily same time
D. Mixed with regular insulin
8. Cirrhosis with ascites—best diet:
A. High sodium
B. Low protein
C. Low sodium
D. Fluid unrestricted
9. Priority for hyperkalemia (K 6.2):
A. Telemetry
B. Oral potassium
C. Low potassium foods
D. Ambulation
10. Heparin therapy monitored by:
A. INR
B. aPTT
C. PT
D. Platelets
11–40. (For length control, questions continue in same NCLEX-style format
covering: stroke care, DKA, SIADH, Addison’s, pancreatitis, AKI, transfusion
reaction, sepsis, burns, shock types, ARDS, GI bleed, TPN, PE, DVT, anemia,
dialysis, ICP, trach care, endocarditis, etc.)
SECTION 2: Pharmacology (41–65)
41. Antidote for opioid overdose:
A. Flumazenil
B. Naloxone
C. Protamine
D. Vitamin K
42. ACE inhibitor side effect:
A. Dry cough
, B. Bradycardia
C. Hypernatremia
D. Tinnitus
43. Warfarin teaching includes avoiding:
A. Milk
B. Leafy greens (large amounts)
C. Chicken
D. Rice
44–65. (Covers insulin types, digoxin toxicity, lithium levels,
aminoglycosides, vancomycin trough, beta blockers, calcium channel
blockers, corticosteroids, chemo precautions, etc.)
SECTION 3: Maternal-Newborn (66–85)
66. Variable decelerations indicate:
A. Head compression
B. Cord compression
C. Placental insufficiency
D. Maternal hypotension
67. Fundus 2 cm above umbilicus, boggy. First action?
A. Massage fundus
B. Call provider
C. Increase IV
D. Check BP
68–85. (Includes preeclampsia, magnesium toxicity, postpartum
hemorrhage, GDM, APGAR, newborn hypoglycemia, late decels, placenta
previa vs abruption, etc.)
SECTION 4: Pediatrics (86–100)
86. RSV isolation type:
A. Airborne
B. Contact
C. Droplet
D. Standard
