BIOL 3200 Final Exam (Dr. Mehari - Auburn) Study
Questions and Answers
Why is antibiotic treatment of Gram-negative bacteria NOT always a good idea? - CORRECT
ANSWER it can result in release of endotoxin
The ability to survive in the harsh environment of the phagolysosome is a virulence factor
produced by - CORRECT ANSWER Coxiella burnetti
What type of toxin is the Shiga toxin of E. coli (O157:H7)? - CORRECT ANSWER protein
synthesis inhibitor
Match the organism with the virulence factor
Organisms:
- Pseudomonas aeruginosa
- Yersinia pestis
- Bordetella pertussis
- Staphylococcus aureus
Factors:
- type IV secretion system
- type II secretion system
- type III secretion system
- protein A
- capsule
- Shiga toxin - CORRECT ANSWER - Pseudomonas aeruginosa: type II secretion system
, - Yersinia pestis: type III secretion system
- Bordetella pertussis: type IV secretion system
- Staphylococcus aureus: protein A
All of the following are bacterial structures responsible for attachment to the host cells or
structures EXCEPT
- LPS of E. coli
- type I pili of E. coli
- type IV pili of Neisseria meningitidis
- pertactin of Bordetella pertussis
- protein M of Streptococcus pyogenes - CORRECT ANSWER LPS of E. coli
Shiga toxins of E. coli O157:H7 mechanism of killing affected cells is due to - CORRECT
ANSWER protein synthesis inhibitor
The cholera toxin causes ADP-ribosylation of its target cells and is an example of - CORRECT
ANSWER an enterotoxin that disrupts function of the intestine
The toxin of ___ consists of two active toxins: an edema factor and a lethal factor - CORRECT
ANSWER Bacillus anthracis
Neisseria gonorrhoeae is a Gram-negative diplococcus that typically causes symptomatic
infections in males. The presence of Neisseria gonorrhoeae is urethral pus in diagnostic for
gonorrhoeae in males. What would be observed in a positive Gram stain? - CORRECT
ANSWER paired red spheres
After staining the background, many strains of B. pertussis resemble the staining pattern shown
in the figure below. What structure do they possess that contributes to their virulence? -
CORRECT ANSWER capsule
Based on your knowledge of microbial genetics and microbial pathogenesis, where do you think
the genetic information for endotoxins are located? - CORRECT ANSWER chromosomes
Match the organism with the virulence factors
Organisms:
- Treponema palladium
- Staphylococcus aureus
- Helicobacter pylori
Questions and Answers
Why is antibiotic treatment of Gram-negative bacteria NOT always a good idea? - CORRECT
ANSWER it can result in release of endotoxin
The ability to survive in the harsh environment of the phagolysosome is a virulence factor
produced by - CORRECT ANSWER Coxiella burnetti
What type of toxin is the Shiga toxin of E. coli (O157:H7)? - CORRECT ANSWER protein
synthesis inhibitor
Match the organism with the virulence factor
Organisms:
- Pseudomonas aeruginosa
- Yersinia pestis
- Bordetella pertussis
- Staphylococcus aureus
Factors:
- type IV secretion system
- type II secretion system
- type III secretion system
- protein A
- capsule
- Shiga toxin - CORRECT ANSWER - Pseudomonas aeruginosa: type II secretion system
, - Yersinia pestis: type III secretion system
- Bordetella pertussis: type IV secretion system
- Staphylococcus aureus: protein A
All of the following are bacterial structures responsible for attachment to the host cells or
structures EXCEPT
- LPS of E. coli
- type I pili of E. coli
- type IV pili of Neisseria meningitidis
- pertactin of Bordetella pertussis
- protein M of Streptococcus pyogenes - CORRECT ANSWER LPS of E. coli
Shiga toxins of E. coli O157:H7 mechanism of killing affected cells is due to - CORRECT
ANSWER protein synthesis inhibitor
The cholera toxin causes ADP-ribosylation of its target cells and is an example of - CORRECT
ANSWER an enterotoxin that disrupts function of the intestine
The toxin of ___ consists of two active toxins: an edema factor and a lethal factor - CORRECT
ANSWER Bacillus anthracis
Neisseria gonorrhoeae is a Gram-negative diplococcus that typically causes symptomatic
infections in males. The presence of Neisseria gonorrhoeae is urethral pus in diagnostic for
gonorrhoeae in males. What would be observed in a positive Gram stain? - CORRECT
ANSWER paired red spheres
After staining the background, many strains of B. pertussis resemble the staining pattern shown
in the figure below. What structure do they possess that contributes to their virulence? -
CORRECT ANSWER capsule
Based on your knowledge of microbial genetics and microbial pathogenesis, where do you think
the genetic information for endotoxins are located? - CORRECT ANSWER chromosomes
Match the organism with the virulence factors
Organisms:
- Treponema palladium
- Staphylococcus aureus
- Helicobacter pylori
