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1. A patient reports epigastric burning that worsens after
meals and when lying down. Most likely diagnosis?
A. Migraine
B. Gastroesophageal reflux disease (GERD)
C. Otitis media
D. Nephrolithiasis
Rationale: Heartburn after meals and supine symptoms are
classic for GERD.
2. Which lifestyle change may improve GERD symptoms?
A. Large late-night meals
B. Elevate head of bed and avoid late meals
C. Lie flat after eating
D. Smoke more frequently
Rationale: Reducing reflux triggers and nighttime reflux can
improve symptoms.
3. Which medication class commonly treats GERD?
A. Antibiotics
B. Proton pump inhibitors
, C. Anticoagulants
D. Opioids only
Rationale: PPIs reduce gastric acid production and are
effective therapy.
4. Which alarm symptom with GERD warrants further
evaluation?
A. Mild burping only
B. Dysphagia and weight loss
C. Occasional heartburn only
D. Brief hiccups only
Rationale: Difficulty swallowing and weight loss may indicate
serious pathology.
5. Which organism is strongly associated with peptic ulcer
disease?
A. RSV
B. Helicobacter pylori
C. Influenza virus
D. Candida only
Rationale: H. pylori is a common cause of ulcers.
6. Which medication class also contributes to peptic ulcer
disease?
A. Intranasal saline
, B. NSAIDs
C. Fiber supplements
D. Topical moisturizers
Rationale: NSAIDs impair gastric mucosal protection.
7. Which symptom suggests upper GI bleeding?
A. Clear rhinorrhea only
B. Melena or coffee-ground emesis
C. Mild sneezing only
D. Urinary frequency only
Rationale: Digested blood may appear as black stool or coffee-
ground emesis.
8. Which patient with abdominal pain needs emergency
evaluation?
A. Mild bloating only
B. Rigid abdomen with hypotension
C. Stable reflux only
D. Mild gas after meal
Rationale: Peritonitis or shock signs require immediate care.
9. Which symptom suggests acute appendicitis?
A. LUQ pain only
B. Periumbilical pain migrating to RLQ
, C. Heartburn only
D. Dysuria only
Rationale: Classic appendicitis pain migrates to the right
lower quadrant.
10. Which symptom commonly accompanies appendicitis?
A. Improved appetite only
B. Nausea and anorexia
C. Productive cough only
D. Sneezing only
Rationale: GI inflammation commonly causes nausea and loss
of appetite.
11. Which symptom suggests acute cholecystitis?
A. Toe pain only
B. RUQ pain after fatty meal with fever
C. Dry lips only
D. Sinus pressure only
Rationale: Gallbladder inflammation often causes RUQ pain
and fever.
12. Which imaging is commonly used first for gallbladder
disease?
A. EEG
B. RUQ ultrasound