NAPLEX Top Drugs Antibiotics, Antivirals, & Anti-Infective
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Real Exam Questions And Correct Answers (Verified Answers)
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Identify commonly used anti-infective agents, their spectrum of
activity, and primary indications relevant to NAPLEX. (72 cards)
1
Q
What is the common brand name(s) for:
acyclovir
(ay-SYE-kloe-veer)
A
Zovirax
Class: Antiviral
Indication: Treats HSV; VZV; prophylaxis of CMV; chickenpox; herpes
simplex encephalitis
MOA: Inhibits DNA polymerase; requires conversion by thymidine
kinase for viral replication inhibition
Side Effects: Usually well tolerated headache; GI upset; skin reactions;
blood dyscrasia; hepatitis; renal failure
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Increase fluid intake with IV acyclovir to reduce renal damage
Caution in renal impairment
2
,Q
What is the common brand name(s) for:
albendazole
(al-BEN-da-zole)
A
Albenza
Class: Anthelmintic
Indication: Treats HSV; VZV; prophylaxis of CMV; chickenpox; herpes
simplex encephalitis
MOA: Inhibits DNA polymerase; requires conversion by thymidine
kinase for viral replication inhibition
Side Effects: Usually well tolerated. Headache; GI upset; skin
reactions; blood dyscrasia; hepatitis; renal failure
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Increase fluid intake with IV acyclovir to reduce renal damage
Caution in renal impairment
3
Q
What is the common brand name(s) for:
amikacin
(am-i-KAY-sin)
A
Amikin
Class: Aminoglycosides
,Indication: Treats infections by strains of Proteus, Pseudomonas,
Enterobacter, Serratia; joint infections; intra-abdominal infections;
meningitis; pneumonia; sepsis; UTIs; multidrug-resistant
Mycobacterium tuberculosis
MOA: Binds to the 30S ribosomal subunit, interfering with protein
synthesis and causing misreading of the genetic code
Side Effects: Nephrotoxicity; ototoxicity; vestibular toxicity; cochlear
toxicity; drug-induced renal failure; hypersensitivity
Contraindications: Pregnancy
Considerations:
Adjust dosing in renal impairment
Once-daily dosing preferred to reduce toxicity
Reserved for serious infections
Baseline auditory and renal function assessment recommended
Boxed warning for neurotoxicity
4
Q
What is the common brand name(s) for:
amoxicillin
(a-MOX-i-sil-in)
A
Amoxil
Class: Penicillin
Indication: Treats ear, nose, and throat infections; H. pylori; lower
respiratory infections; rhinosinusitis; skin and soft tissue infections;
UTIs; Lyme disease; peritonitis
, MOA: Bactericidal; inhibits bacterial cell wall synthesis by binding to
penicillin-binding proteins
Side Effects: Maculopapular rash; seizures (high dose); diarrhea;
superinfections; pseudomembranous colitis; vaginal candidiasis;
hypersensitivity reactions
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Dose adjustments in renal impairment
Use appropriate dosing to minimize resistance
Complete full course of therapy
Decreased effectiveness of birth control
5
Q
What is the common brand name(s) for:
amoxicillin; clavulanate
(a-MOX-i-sil-in; KLAV-yoo-la-nate)
A
Augmentin
Class: Penicillin and Beta-Lactam Combination
Indication: Treats acute otitis media; sinusitis; community-acquired
pneumonia; UTIs; skin and soft tissue infections; lower respiratory
tract infections
MOA: Amoxicillin inhibits bacterial cell wall synthesis; clavulanate
inhibits beta-lactamase, protecting amoxicillin from degradation
Side Effects: Diarrhea; nausea; vomiting; abdominal pain; rash;
elevated liver enzymes
Agents Exam | Most Recent Exam 2026-2027 Actual Complete
Real Exam Questions And Correct Answers (Verified Answers)
Already Graded A+ |Guaranteed Success!! Newest Exam | Just
Released!!
Identify commonly used anti-infective agents, their spectrum of
activity, and primary indications relevant to NAPLEX. (72 cards)
1
Q
What is the common brand name(s) for:
acyclovir
(ay-SYE-kloe-veer)
A
Zovirax
Class: Antiviral
Indication: Treats HSV; VZV; prophylaxis of CMV; chickenpox; herpes
simplex encephalitis
MOA: Inhibits DNA polymerase; requires conversion by thymidine
kinase for viral replication inhibition
Side Effects: Usually well tolerated headache; GI upset; skin reactions;
blood dyscrasia; hepatitis; renal failure
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Increase fluid intake with IV acyclovir to reduce renal damage
Caution in renal impairment
2
,Q
What is the common brand name(s) for:
albendazole
(al-BEN-da-zole)
A
Albenza
Class: Anthelmintic
Indication: Treats HSV; VZV; prophylaxis of CMV; chickenpox; herpes
simplex encephalitis
MOA: Inhibits DNA polymerase; requires conversion by thymidine
kinase for viral replication inhibition
Side Effects: Usually well tolerated. Headache; GI upset; skin
reactions; blood dyscrasia; hepatitis; renal failure
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Increase fluid intake with IV acyclovir to reduce renal damage
Caution in renal impairment
3
Q
What is the common brand name(s) for:
amikacin
(am-i-KAY-sin)
A
Amikin
Class: Aminoglycosides
,Indication: Treats infections by strains of Proteus, Pseudomonas,
Enterobacter, Serratia; joint infections; intra-abdominal infections;
meningitis; pneumonia; sepsis; UTIs; multidrug-resistant
Mycobacterium tuberculosis
MOA: Binds to the 30S ribosomal subunit, interfering with protein
synthesis and causing misreading of the genetic code
Side Effects: Nephrotoxicity; ototoxicity; vestibular toxicity; cochlear
toxicity; drug-induced renal failure; hypersensitivity
Contraindications: Pregnancy
Considerations:
Adjust dosing in renal impairment
Once-daily dosing preferred to reduce toxicity
Reserved for serious infections
Baseline auditory and renal function assessment recommended
Boxed warning for neurotoxicity
4
Q
What is the common brand name(s) for:
amoxicillin
(a-MOX-i-sil-in)
A
Amoxil
Class: Penicillin
Indication: Treats ear, nose, and throat infections; H. pylori; lower
respiratory infections; rhinosinusitis; skin and soft tissue infections;
UTIs; Lyme disease; peritonitis
, MOA: Bactericidal; inhibits bacterial cell wall synthesis by binding to
penicillin-binding proteins
Side Effects: Maculopapular rash; seizures (high dose); diarrhea;
superinfections; pseudomembranous colitis; vaginal candidiasis;
hypersensitivity reactions
Contraindications: Hypersensitivity to the drug or its components
Considerations:
Dose adjustments in renal impairment
Use appropriate dosing to minimize resistance
Complete full course of therapy
Decreased effectiveness of birth control
5
Q
What is the common brand name(s) for:
amoxicillin; clavulanate
(a-MOX-i-sil-in; KLAV-yoo-la-nate)
A
Augmentin
Class: Penicillin and Beta-Lactam Combination
Indication: Treats acute otitis media; sinusitis; community-acquired
pneumonia; UTIs; skin and soft tissue infections; lower respiratory
tract infections
MOA: Amoxicillin inhibits bacterial cell wall synthesis; clavulanate
inhibits beta-lactamase, protecting amoxicillin from degradation
Side Effects: Diarrhea; nausea; vomiting; abdominal pain; rash;
elevated liver enzymes
