Neurobiology /2027 Verified Graded A+ Already Passed!!!

Neurobiology /2027 Verified Graded A+ Already Passed!!! What are the three major hypotheses of psychosis and their neurotransmitter networks? - Correct Answer Dopamine theory - hyperactive dopamine at D2 receptors in the mesolimbic pathway Glutamate theory - NMDA receptor hypofunction Serotonin theory - 5HT2A receptor hyperfunction in the cortex (Stahl Ch 4, p. 79) Briefly explain the dopamine hypothesis of the positive and negative symptoms of schizophrenia. - Correct Answer The dopamine hypothesis of schizophrenia consists of: There is too much dopamine activity in the mesolimbic dopamine pathway, which leads to positive symptoms (such as hallucinations and delusions). There is also too little dopamine activity in the mesocortical dopamine pathway, which leads to negative symptoms (such as blunting of affect, poverty of speech, anhedonia, and so on). What pathway is responsible for regulating dopamine in the hypothalamus and affects the release of prolactin? a Mesolimbic pathway b Substantia nigra c Mesocortical pathway d Tuberoinfundibular pathway - Correct Answer Tuberoinfundibular pathway Drug-induced Parkinson's is caused by a decrease of dopamine in what pathway? a Substantia nigra b Mesolimbic pathway c Mesocortical pathway d Nigrostriatal pathway - Correct Answer Nigrostriatal pathway Brodmann's areas are differentiated by the: