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NSG 318 EXAM 4
Introduction to Pharmacology - GCU
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NSG 318 EXAM 4
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Blueprint for NSG 318 Exam #4
(Final)
NSG-318 EXAM 4 (Final) Student Percent
Blueprint Level of Bloom’s taxonomy of exam/
# of
Insulin YouTube video: Pharmacology for Nursing - Diabetic drugs Insulin Types & question
Topic 1: Introduction to Nursing Pharmacology, Terminology, and Medication Calculation 7%
1.4 Apply principles of dimensional analysis to calculate medication dosages 3
1.5 Discuss the measures followed by the nurse to ensure medications are administered safely 2
Nurse Responsibilites:
● 6 rights (right drug, right patient, right time, right dose, right route, right documentation)
● Right patient- 2 identifiers first & last name, date of birth
● Check vital signs (blood pressure, pulse, respiratory rate, oxygen saturation, pain &
anxiety level)
o Normal vital signs for
adult are: BP 120/80
HR 60-100 beats per
minute RR 12-20
breaths per minute
temperature 97.8 – 99
F
oxygen sat 95-100%
● Perform focused assessment (related to the patients complaint/reason for being there)
● Verify and double check medication prescription (are all components of
prescription/order there?)
o The components of a drug order are as follows:
• Patient name and birth date
• Date the order is written
• Provider signature or name if an electronic order, T/O, or V/O
• Signature of licensed staff who took the T/O or V/O, if applicable
• HCPs who wish to prescribe controlled drugs must register with the US
Federal Drug Enforcement Agency (DEA); when prescribing controlled
substances, the HCP’s DEA number must be on the prescription
*Example of a drug order.
• Drug name and strength
• Drug frequency or dose (e.g., once daily)
• Route of administration
• Duration of administration (e.g., ×7 days, ×3 doses, when applicable)
• Number of patient refills
• Number of pills to be dispensed
• Any special instructions for withholding or adjusting dosage based on
nursing assessment, drug effectiveness, or laboratory results
● Clarify prescription (if missing any components or possibly unsafe for patient).
● Consider patients most recent labwork, vital signs, physical condition before
administering meds
● Keep environment clean and clear, no distractions when getting meds
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Blueprint for NSG 318 Exam #4 (Final)
NSG-318 EXAM 4 (Final) Student Percent
Blueprint Level of Bloom’s taxonomy of exam/
# of
Insulin YouTube video: Pharmacology for Nursing - Diabetic drugs Insulin Types & question
Topic 2: Drugs and the Body: Pharmacodynamics, Pharmacokinetics, and Pharmacogenetics 3%
2.1 Differentiate among pharmacokinetics, pharmacodynamics, and pharmacogenetics 2
● Pharmacokinetics is the movement of drugs through the body (how medications get
from point of entry to the site of action). What the body does to the drug
o Factors affecting Pharmacokinetics: blood circulation, pain/stress, food texture,
food fat content, temp, pH, route of administration
o The processes of Pharmacokinetics are:
▪ Absorption-drug moving into the bloodstream from administration site
(80% are oral so from GI tract into bloodstream) 100% of IV drugs go
into bloodsteam
● Disintegration: breakdown of oral drug into small particles
● Dissolution: process of combining small drug particles with
liquid to form a solution
▪ Distribution- drug moves from circulation (bloodstream) to the body
tissues
● Protein-binding= drugs will bind with plasma proteins
which are albumin, lipoprotein, and AGP (alpha-1-acid-
glycoprotein)
● The portion of the drug bound to protein is inactive because it is
not available to interact with tissue receptors and therefore is
unable to exert a pharmacologic effect. The portion that remains
unbound is free, active drug. Free drugs are able to exit blood
vessels and reach their site of action, causing a pharmacologic
response.
● Two highly protein-bound drugs administered together
compete for protein- binding sites and highest % wins.
Example: warfarin (99%) and furosemide (95%) administered
together warfarin could displace furosemide so that more
furosemide is “free/active” which can lead to toxicity.
● Patients with liver or kidney disease have low serum albumin
levels so less protein-binding sites so more of the “free drug”
available and possible toxicity.
● Blood Brain Barrier (BBB)- blood vessels in brain have special
endothelial lining where cells are pressed together (called tight
junctions) that protects brain and keeps 98% of all drugs out.
o Highly lipid soluble and low molecular weight drugs
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