NRNP 6665 Midterm Exam Study Guide
Questions And Answers [Verified Answers]
Plus Rationales Latest 2026/27 | Qs & Ans
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1. Which neurotransmitter is most associated with reward
pathways and psychosis?
A. Serotonin
B. Dopamine
C. Histamine
D. Acetylcholine
Rationale: Dopamine plays a major role in reward circuitry
and psychosis theories.
2. Which neurotransmitter is commonly linked to mood
regulation and anxiety?
A. Potassium
B. Serotonin
C. Calcium
D. Insulin
Rationale: Serotonin influences mood, anxiety, sleep, and
appetite.
, 3. Which brain region is strongly involved in fear responses?
A. Cerebellum
B. Amygdala
C. Occipital lobe
D. Medulla only
Rationale: The amygdala is central to fear and threat
processing.
4. Which brain region is associated with executive function and
judgment?
A. Temporal lobe only
B. Prefrontal cortex
C. Brainstem only
D. Cerebellum only
Rationale: The prefrontal cortex supports planning and
decision-making.
5. Which DSM diagnosis requires at least one manic episode?
A. Cyclothymic disorder
B. Bipolar I disorder
C. Persistent depressive disorder
D. OCD
Rationale: Bipolar I is defined by mania.
, 6. Which symptom best defines mania?
A. Mild sadness only
B. Elevated mood, decreased need for sleep, impaired
judgment
C. Seasonal worry only
D. Mild fatigue only
Rationale: Mania includes elevated/irritable mood with
increased energy and impairment.
7. Which disorder includes hypomania plus major depression?
A. Bipolar I disorder
B. Bipolar II disorder
C. Schizoaffective disorder
D. Panic disorder
Rationale: Bipolar II requires hypomania and major
depressive episodes.
8. Which symptom suggests major depressive disorder?
A. Euphoric mood only
B. Anhedonia with depressed mood and fatigue
C. Delusions only
D. Hyperactivity only
Rationale: Core depressive symptoms include depressed mood
or loss of interest.
, 9. Minimum duration commonly required for major depressive
episode?
A. 2 days
B. 2 weeks
C. 2 months only
D. 1 year only
Rationale: DSM criteria require symptoms for at least 2 weeks.
10. Which medication class is often first-line for
depression?
A. Antipsychotics only
B. SSRIs
C. Stimulants only
D. Antacids only
Rationale: SSRIs are common first-line treatment options.
11. Which side effect may occur early with SSRIs?
A. Broken bone
B. Nausea or headache
C. Cataracts
D. Kidney stones
Rationale: GI upset and headache are common early effects.
12. Which serious syndrome can occur with serotonergic
excess?
Questions And Answers [Verified Answers]
Plus Rationales Latest 2026/27 | Qs & Ans
Instant Pdf Download
1. Which neurotransmitter is most associated with reward
pathways and psychosis?
A. Serotonin
B. Dopamine
C. Histamine
D. Acetylcholine
Rationale: Dopamine plays a major role in reward circuitry
and psychosis theories.
2. Which neurotransmitter is commonly linked to mood
regulation and anxiety?
A. Potassium
B. Serotonin
C. Calcium
D. Insulin
Rationale: Serotonin influences mood, anxiety, sleep, and
appetite.
, 3. Which brain region is strongly involved in fear responses?
A. Cerebellum
B. Amygdala
C. Occipital lobe
D. Medulla only
Rationale: The amygdala is central to fear and threat
processing.
4. Which brain region is associated with executive function and
judgment?
A. Temporal lobe only
B. Prefrontal cortex
C. Brainstem only
D. Cerebellum only
Rationale: The prefrontal cortex supports planning and
decision-making.
5. Which DSM diagnosis requires at least one manic episode?
A. Cyclothymic disorder
B. Bipolar I disorder
C. Persistent depressive disorder
D. OCD
Rationale: Bipolar I is defined by mania.
, 6. Which symptom best defines mania?
A. Mild sadness only
B. Elevated mood, decreased need for sleep, impaired
judgment
C. Seasonal worry only
D. Mild fatigue only
Rationale: Mania includes elevated/irritable mood with
increased energy and impairment.
7. Which disorder includes hypomania plus major depression?
A. Bipolar I disorder
B. Bipolar II disorder
C. Schizoaffective disorder
D. Panic disorder
Rationale: Bipolar II requires hypomania and major
depressive episodes.
8. Which symptom suggests major depressive disorder?
A. Euphoric mood only
B. Anhedonia with depressed mood and fatigue
C. Delusions only
D. Hyperactivity only
Rationale: Core depressive symptoms include depressed mood
or loss of interest.
, 9. Minimum duration commonly required for major depressive
episode?
A. 2 days
B. 2 weeks
C. 2 months only
D. 1 year only
Rationale: DSM criteria require symptoms for at least 2 weeks.
10. Which medication class is often first-line for
depression?
A. Antipsychotics only
B. SSRIs
C. Stimulants only
D. Antacids only
Rationale: SSRIs are common first-line treatment options.
11. Which side effect may occur early with SSRIs?
A. Broken bone
B. Nausea or headache
C. Cataracts
D. Kidney stones
Rationale: GI upset and headache are common early effects.
12. Which serious syndrome can occur with serotonergic
excess?
