Menopause Society Actual Exam
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1. Climacteric phase - ANSWER The period of endocrinology, somatic, and
transitory psychologic changes that occur around the time of menopause.
2. Early menopause - ANSWER LMP before age 45
3. Late menopause - ANSWER LMP after age 54
4. Primary ovarian insufficiency - ANSWER Menopause that occurs before
age 40
5. Location of estrogen receptors - ANSWER Vagina, vulva, urethra, trigone
of the bladder
6. Effects of estrogen on tissue - ANSWER maintain blood flow, the collagen,
and HA within the epithelial surfaces. Supports microbiome and protects
tissue from pathogens.
7. Vaginal changes with menopause - ANSWER Thinning, loss of elasticity,
loss or absence or rugae.
,8. Vagina and urethra in menopause - ANSWER vagina narrows, urethra
moves closer to the introitus.
9. Stress urinary incontinence - ANSWER Vaginal estrogen and urinary
incontinence: what type does it help with?
10.Treatment for FPHL - ANSWER Minoxidil, spironolactone, finasteride,
estrogen therapy
11.Late reporoductive years -3b and -3a. What happens with menstrual cycles,
FSH, AMH, AFC, inhibin? - ANSWER -3b: menstrual cycles normal, FSH
normal, AMH low, AFC low, inhibin low.
-3a: subtle menstrual changes, variable FSH, AMH low, AFC low, inhibin low.
12.When it is appropriate to check an FSH during the cycle if you check it? and
why? - ANSWER Cycle day #3. Elevated estradiol can suppress FSH
giving a falsely normal FSH level.
13.AMH
14.produced by...
15.used to test...
16.Is it a screening tool for fertility?
17.When does it peak? - ANSWER produced by granulosa cells
used to test damage to ovarian follicle reserve. If AMH is low, the woman has a
low ovarian reserve.
,not recommended as a screening tool to predict fertility.
Peaks at around 25 years old. So before age 25, this test is not helpful.
It is influenced by exogenous hormones. Lower in hormonal contraception
users, but increases after d/cing.
18.AFC - ANSWER Antral follicle count
Number of follicles that are detectable with ultrasound.
They are sensitive to FSH and considered to represent the availability poo of
follicles.
19.Late menopause transition (-1) FSH level on random draw - ANSWER 25
or higher
20.Black women have higher or lower FSH levels? - ANSWER Higher
21.Early menopause transition (stage -2) - ANSWER Persistent difference of 7
days or more in the length of consecutive cycles.
22.Late menopause transition (stage -1) - ANSWER 60 or more consecutive
days of amenorrhea
23.Luteal out of phase event (LOOP) - ANSWER Explains why some
perimenopausal women have elevated estrogen level sometimes...In the
early menopause transition, elevated FSH levels are adequate to recruit a
second follicle which results in a follicular phase-like rise in estradiol
secretion superimposed on the mid-to-late luteal phase of the ongoing
ovulatory cycle.
, 24.Obese women and estradiol levels during menopause - ANSWER Obese
women are more likely to have anovulatory cycles with high estradiol levels.
They are also more likely to have lower premenopause yet higher
postmenopause estradiol levels compared with women of normal weight.
(why they are at higher risk of endometrial cancer)
25.Chinese and Japanese women - ANSWER These ethnic groups have lower
estradiol levels then white, black and hispanic women.
26.stage +2 - ANSWER late menopause stage: 5-8 years after FMP. Somatic
aging predominates. Increased genitourinary symptoms.
27.Stages +1a, +1b, +1c - ANSWER early post menopause: 2 years after FMP.
FSH rises, estradiol decreases. VMS predominate.
28.Elevated FSH, LH - ANSWER Endocrine labs after menopause
29.AMH, inhibin B - ANSWER These hormones work during reproductive
years to not deplete follicle pool too quickly.
30.Phases during menopause transition and PMS symptoms - ANSWER
Menstrual cycle shortens, follicular phase compresses, women spend more
time in luteal phase.. meaning more premenstrual symptoms and more
frequent menstrual periods.
31.How to respond if a patient requests FSH lab? - ANSWER many pitfalls,
variable depending on the day of the cycle you draw the lab, normal or low
FSH is not helpful.