PAPER 2026 COMPREHENSIVE QUESTIONS
AND SOLUTIONS ACCURATE CONTENT
GRADED A+
⩥ An 84-year-old female patient is being treated for pneumonia. Her
condition is deteriorating despite aggressive broad spectrum
antipseudomonal cephalosporin antibiotic therapy. Induced sputum
culture reveals heavy growth of Legionella pneumophilia. The AGACNP
knows that antibiotic therapy must be adjusted to include coverage with.
Answer: Azithromycin 500mg PO daily
Clarithromycin 500mg PO BID
OR
Levofloxacin 750mg PO daily
10-14 day course
⩥ What is contraindicated for corneal abrasions? Answer: Ophthalmic
corticosteroids
⩥ A 41-year-old male patient is in the intensive care unit with septic
shock and has been aggressively managed with broad spectrum
antibiotics. He has become progressively hypoxemic and the last arterial
blood gas revealed a paO2 of 58 mm Hg. Chest radiography reveals a
"white out" pattern bilaterally. The patient is intubated and ventilated.
, The AGACNP knows that appropriate management must include
Answer: Adjust the PEEP as the patient is experiencing ARDS
⩥ What is an absolute indication for treating otitis media with
antibiotics? Answer: Fever >102.2*F or moderate to severe ear pain.
⩥ What risk is associated with an FIO2>60% in a patient being
mechanically ventilated? Answer: there is an increased risk of oxygen
conversion to oxygen free radical which can cause damage to the lung
parenchyma.
⩥ Acute respiratory distress syndrome (ARDS) occurs when an
overwhelming systemic insult results in which maladaptive physiologic
response? Answer: An increase in the permeability of the alveolar
capillary membrane, which allows protein and other intravascular
solutes to leak out of the pulmonary vessels into the alveoli resulting in
decreased ability to ventilate the alveoli and ultimately right to left
shunting.
⩥ Acute respiratory distress syndrome is characterized by which
abnormality of ventilation and perfusion? Answer: Right to left shunting.
A shunt occurs when blood flows from the right side of the heart to the
left side of the heart without any contact with aerated alveoli as occurs in
ARDS.