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Integrate knowledge of airway management, perioperative physiology, patient
safety, communication, ethics, and human factors in anaesthetic practice. (165
cards)
1
Q
List anatomical factors that can complicate intubation.
ANSWERS:
Small mouth
Receding chin
High arched palate
Large tongue
Acquired injuries (e.g., burns, tumors)
Poor dentition (e.g., loose teeth)
TMJ disease limiting mouth opening
Adenotonsillar hypertrophy
2
Q
What are the principles for managing patients with a subarachnoid
haemorrhage requiring endovascular coil insertion?
ANSWERS:
Secure airway and maintain normoxia and normocapnia
, Maintain stable cerebral perfusion pressure
Treat pain and seizures
3
Q
Which reflexes are tested in brainstem death testing?
ANSWERS:
Pupillary light (II + III)
Corneal (V + VII)
Facial pain (V + VII)
Vestibulo-ocular reflex (VIII + III/IV/VI)
Gag reflex (IX + X)
Cough reflex (X + X)
4
Q
What local anaesthetic blocks may be used for superficial facial surgery?
ANSWERS:
Infratrochlear (eyelids, nose and conjunctivae)
Supraorbital and supratrochlear (forehead)
Infraorbital (lower eyelid and upper lip)
Mental (chin and lower lip)
5
Q
Which types of operation may need facial nerve monitoring?
ANSWERS:
, Parotidectomy
Middle ear surgery (e.g. mastoidectomy)
Posterior fossa surgery (e.g. acoustic neuroma)
6
Q
How does the 2,3-DPG level change in stored blood?
ANSWERS:
Stored blood quickly loses 2,3-DPG and its ability to deliver oxygen.
7
Q
Briefly describe the pathophysiology of thalassemia.
ANSWERS:
There are four alpha globin genes on chromosome 14
Alpha thalassemia results from mutations to 1 to 4 of these genes
There are two beta globin genes on chromosome 11
Mutations in these genes cause beta thalassemia
It usually manifests at 6 months of age when HbA takes over from HbF
8
Q
Which mutation causes sickle cell disease?
ANSWERS:
Glutamic acid is substituted for valine at position 6 of the beta globin chain.
9
Q
, What is malignant hyperthermia?
ANSWERS:
Rare autosomal dominant (chromosome 19) condition that can be triggered by
volatile agents and suxamethonium.
Incidence of 1 in 10,000.
10
Q
What are the clinical manifestations of malignant hyperthermia?
ANSWERS:
Muscle rigidity
Tachycardia
Rising ETCO₂
Increased oxygen requirement
Hyperpyrexia
Metabolic and respiratory acidosis
11
Q
Outline the pathophysiology of malignant hyperthermia.
ANSWERS:
Triggering agents (volatiles or suxamethonium) causes uncontrolled release of
free calcium from the sarcoplasmic reticulum due to a mutation in the
ryanodine receptor of the sarcoplasmic reticulum.
12
Q
What measures should be taken for a patient at risk of malignant
hyperthermia?