COMSAE 107 (Latest 2026/2027) Complete
Questions and 100% Correct Answers
(Guaranteed Pass)
• DMARD drug for UC/Crohns/RA . Answer: sulfasalazine
• pulmonary effects of CF . Answer: chronic bronchitis and bronchiectasis
• osteoporosis affects what parts of bone? . Answer: (spongy and ) trabecular bone
mass loss
• imipramine . Answer: TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension-
block alpha1)
• viscerosomatic . Answer: visceral disease --> somatic finding
• loratidine vs ranitidine . Answer: loratidine: 2nd gen H1 blocker, doesnt cross BBB -->
less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
• cells w RBCs inside . Answer: entaemoba histolytica
• which type of pneumothorax causes tracheal deviation to the contra side? . Answer:
tension
• intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous
tortuous vessels . Answer: AVM arteriovenous malformation
• cavernous hemangioma . Answer: benign tumor of liver, A/W VHL
• anti-HepB surface antibody is only present in what pop . Answer: recovered or
immunized
not in chronic or
• proctalgia fugax . Answer: levator ani syndrome
,• fasciculus is UMN or LMN lesion? . Answer: LMN
• ectopic gastric tissue . Answer: meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
• antibodies in hashimotos attacks . Answer: thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
• 2 factors that influence starling curve . Answer: x axis- preload (EDV)
y axis- stroke volume or CO
• treatment for fibromyalgia . Answer: TCA, SNRIs anticonvulsants
• what blocks NE reuptake? . Answer: TCA or SNRIs
• possible complication of pagets bone disease . Answer: osteocarcoma
• what does Hct tell you? . Answer: ratio of volume of RBCs compared to total blood
volume
• probenecid . Answer: inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
• 2 causes of SCID . Answer: ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
• lithiums effects on urination . Answer: inhibits vasopression/ADH --> increased urinary
frequency
• infertility drug that can result in multiple fetuses . Answer: clomiphene (clones- multiple
babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
,• AFP levels in down syndrome . Answer: low
• GI malformation A/W down syndrome . Answer: Hirschprungs- congenital aganglionic
megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
• myasthenia gravis associations . Answer: thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
• tx for tinea . Answer: azoles
• beta blockers for asthma . Answer: none- even beta 1s can be nonselective at higher
doses
• what kind of teratogenic effects are seen w ACE/ARBs . Answer: fetal renal agenesis
• stones bones groans moans psych overtones . Answer: high Ca or PTH
• PTH is made by what cells? . Answer: chief cells of parathyroid gland
• PTH inhibits reabsorption of phosphate where? increases calcium resorption where? .
Answer: PO4- proximal tubule
ca- DCT
• anterior innominate rotation means tight hip flexors or extensors? . Answer: extensor-
hamstrings
• thoracic CS . Answer: E SaRa
• most common cause of cellultis . Answer: staph aureus, strep pyogenes
• FPR- direct or indirect? active or passive? . Answer: indirect- place them in position of
diagnosis
passive
• cant treat kid w tetracycline so what do you give? . Answer: amoxicillin
• which Heps are there currently vaccines for? . Answer: A and B (and so by virtue, also
D)
, • why does Hep D need Hep B? . Answer: Hep D utilizes the HBV surface antigen as its
envelope?
• most common hepatitis A/W IVDA in the US . Answer: hep c
• roseola . Answer: 4 day high fever
then rash on the trunk (spares face)
affects babies up to 2 years
HHV6- affects CD4 helper cells and kills them off
• erythema infectiosum . Answer: slapped cheek
parvovirus B19
nonspecific fever/prodrome then slapp cheek rash 5 days later, then rash appears on
arms and spreads to trunk/legs
rash can worsen w fever and sun exposure
TORCH infxn so baby in womb that is exposed can lead to hydrops fetalis
• most common STD . Answer: chlamydia
sxs similar to STI plus discharge
will have high neutrophil count
• dimorphic- butterflies . Answer: candida, histo, cocci, paracocci, blasto, sporothrix,
butterflies huge pair of cocc catching stamp
• hip restricted in internal rotation
dx? . Answer: innom outflare
• immune complex in glomerular mesangium 2 days after URI
berger or PSGN? . Answer: berger
PSGN is 2 wks post URI
• kidney ureter viscerosomatic innervation . Answer: T10-11
• college student w nonspecific symptoms
Questions and 100% Correct Answers
(Guaranteed Pass)
• DMARD drug for UC/Crohns/RA . Answer: sulfasalazine
• pulmonary effects of CF . Answer: chronic bronchitis and bronchiectasis
• osteoporosis affects what parts of bone? . Answer: (spongy and ) trabecular bone
mass loss
• imipramine . Answer: TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension-
block alpha1)
• viscerosomatic . Answer: visceral disease --> somatic finding
• loratidine vs ranitidine . Answer: loratidine: 2nd gen H1 blocker, doesnt cross BBB -->
less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
• cells w RBCs inside . Answer: entaemoba histolytica
• which type of pneumothorax causes tracheal deviation to the contra side? . Answer:
tension
• intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous
tortuous vessels . Answer: AVM arteriovenous malformation
• cavernous hemangioma . Answer: benign tumor of liver, A/W VHL
• anti-HepB surface antibody is only present in what pop . Answer: recovered or
immunized
not in chronic or
• proctalgia fugax . Answer: levator ani syndrome
,• fasciculus is UMN or LMN lesion? . Answer: LMN
• ectopic gastric tissue . Answer: meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
• antibodies in hashimotos attacks . Answer: thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
• 2 factors that influence starling curve . Answer: x axis- preload (EDV)
y axis- stroke volume or CO
• treatment for fibromyalgia . Answer: TCA, SNRIs anticonvulsants
• what blocks NE reuptake? . Answer: TCA or SNRIs
• possible complication of pagets bone disease . Answer: osteocarcoma
• what does Hct tell you? . Answer: ratio of volume of RBCs compared to total blood
volume
• probenecid . Answer: inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
• 2 causes of SCID . Answer: ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
• lithiums effects on urination . Answer: inhibits vasopression/ADH --> increased urinary
frequency
• infertility drug that can result in multiple fetuses . Answer: clomiphene (clones- multiple
babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
,• AFP levels in down syndrome . Answer: low
• GI malformation A/W down syndrome . Answer: Hirschprungs- congenital aganglionic
megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
• myasthenia gravis associations . Answer: thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
• tx for tinea . Answer: azoles
• beta blockers for asthma . Answer: none- even beta 1s can be nonselective at higher
doses
• what kind of teratogenic effects are seen w ACE/ARBs . Answer: fetal renal agenesis
• stones bones groans moans psych overtones . Answer: high Ca or PTH
• PTH is made by what cells? . Answer: chief cells of parathyroid gland
• PTH inhibits reabsorption of phosphate where? increases calcium resorption where? .
Answer: PO4- proximal tubule
ca- DCT
• anterior innominate rotation means tight hip flexors or extensors? . Answer: extensor-
hamstrings
• thoracic CS . Answer: E SaRa
• most common cause of cellultis . Answer: staph aureus, strep pyogenes
• FPR- direct or indirect? active or passive? . Answer: indirect- place them in position of
diagnosis
passive
• cant treat kid w tetracycline so what do you give? . Answer: amoxicillin
• which Heps are there currently vaccines for? . Answer: A and B (and so by virtue, also
D)
, • why does Hep D need Hep B? . Answer: Hep D utilizes the HBV surface antigen as its
envelope?
• most common hepatitis A/W IVDA in the US . Answer: hep c
• roseola . Answer: 4 day high fever
then rash on the trunk (spares face)
affects babies up to 2 years
HHV6- affects CD4 helper cells and kills them off
• erythema infectiosum . Answer: slapped cheek
parvovirus B19
nonspecific fever/prodrome then slapp cheek rash 5 days later, then rash appears on
arms and spreads to trunk/legs
rash can worsen w fever and sun exposure
TORCH infxn so baby in womb that is exposed can lead to hydrops fetalis
• most common STD . Answer: chlamydia
sxs similar to STI plus discharge
will have high neutrophil count
• dimorphic- butterflies . Answer: candida, histo, cocci, paracocci, blasto, sporothrix,
butterflies huge pair of cocc catching stamp
• hip restricted in internal rotation
dx? . Answer: innom outflare
• immune complex in glomerular mesangium 2 days after URI
berger or PSGN? . Answer: berger
PSGN is 2 wks post URI
• kidney ureter viscerosomatic innervation . Answer: T10-11
• college student w nonspecific symptoms
