Nuclear Medicine Technology -
Review Questions for Board
Examinations with 100% Correct
Answers
HowAdoesA201TlAdecay?A-
AAnswerAElectronAcaptureAwithAgammaAemissionsAofA0.135AMeVAandA0.167AMeV
WhatAisAtheAroleAofAtheAstandoutsAionAinAtheApreparationAofApharmaceuticalsAlabeledAwithA99
mTc?A-
AAnswerAStannousAChlorideAisAaAreducingAagentAwhichAchangesAofAvalenceAstateAofATcAinApert
echnetate.AItAhasAnoAeffectAonAeitherAtheAamountAofAAl3+AorAtheAradiationAdose.
IfAanAassayAofAaAvialAcontainingA131IAshowsA50AmCiApresentAonAMayA2,AapproximatelyAwhat
AwillAtheAassayAshowAonAMayA18?A-AAnswerA12.5AmCi
IfAaAboneAscanAhasAbeenAorderedAonAaA5-year-
oldAgirl,AandAtheAphysicianAprescribesA62%AofAtheAadultAdoseAtoAbe
given,AhowAmanyAmCiAshouldAbeAadministered?A-AAnswerA12.4AmCi
IfAtheAbiologicalAhalf-lifeAofAanAisotopeAisA6AhAandAtheAphysicalAhalf-
lifeAisA12Ah,AwhatAisAtheAeffectiveAhalf-life?A-AAnswerA4Ahrs
WhichAofAtheAfollowingAisAusedAtoAabbreviateAphysicalAhalfAlife?A-AAnswerATp
TheAphysicalAhalfAlifeAofAaAradionuclideAisAtheAtimeAitAtakes:A-
AAnswerAforAtheAnuclideAtoAdecayAtoAoneAhalfAofAtheAoriginalAactivity
IfAaAkitAhasA310AmCiAofAactivityApresentAatA8:00Aa.m.,AwhatAwillAtheAvialAassayAshowAinA4
AhAandA10AminAifAtheAdecayAfactorAisA0.618?A-AAnswerA192AmCi
AAvialAcontainingA99mTcAisAassayedAatA9AamAandAcontainsA255AmCi.AToAcalculateAtheAremaini
ngAactivityAatA3ApmAwhatAdecayAfactorAwouldAbeAused?A-AAnswerA0.5
AAvialAofAtechnetiumAeluateAcontainsA50AmCi/ml.AIfA4AmlAis
,withdrawnAandAaddedAtoAaAdiphosphonateAkitAcontaining
16AmlAofAsolution,AwhatAvolumeAwouldAthenAneedAtoAbe
withdrawnAtoAprepareAaA20AmCiAdoseAatAthatAmoment?A-AAnswerA2
IfAaApreparationAofA99mTcAmertiatideAhasA60AmCiAofAactivityApresentAatA8:30Aam,AhowAmany
AmCiAwillAbeApresentAatA9Aam?A(DecayAconstantA=A0.944)A-AAnswerA56.6
WhichAofAtheAfollowingAisAboiledAduringApreparation?A-AAnswerAsulfurAcolloid
TheApresenceAofA12AugAAl+3AinA1AmlAofA99mTcAeluateAisA-
AAnswerAChemicalAimpurity;AAlA3+AionsAfromAtheAaluminaAcolumnAofAtheAmustAbeAlessAthanA
10AugAAl3+/mlAofAeluateA-AthisAlimitAisAsetAbyAUSAPharmacopoeia
WhichAbodyAdecidesAonAtheAacceptableAlevelsAofAradionuclidicAimpurity?A-AAnswerANRCA&AUSP
WhichAofAtheAfollowingAisAanAexampleAofAradionuclidicAimpurity:
1)ApresenceAofAfreeA99mTcAinAaApreparationAofA99mTcAsulfurAcolloid
2)APresenceAofA99MoAinA99mTcAeluate
3)ApresenceAofAaluminumAionsAinA99mTcAeluate
4)ApresenceAofApyrogensAinAeluateA-AAnswerA2
WhatAisAtheAmaximumAamountAofAaluminumAionsA(AL3+)AallowedAinAoneAmilliliterAofA99mTcAe
luateAaccordingAtoAtheAUSP?A-AAnswerA10Aμg
WhatAisAindicatedAbyAtheAfrontAofAanAITLCAstrip?A-
AAnswerAThisAdependsAonAtheAsolventAandAstripAused
IfAaAkitAcontainsA140AmCiAofA99mTcAinA23Aml,AhowAmuchAvolumeAmustAbeAwithdrawnAtoAob
tainAaAdoseAofA5AmCi?A-AAnswerA0.8AmLA-
AspecificAconcentrationAisA140AmCi/23AmlAorA6.1AmCi/ml
IfAaAkitAcontainsA140AmCiAofA99mTcAinA23AmlAatA9:00Aa.m.,AhowAmuchAvolumeAmustAbeAwi
thdrawnAtoAobtainAaAdoseAofA5AmCiAatA3:00Ap.m.?A-AAnswerA1.6Aml
, AnAMAAAkitAcontainsA40AmCiAofA99mTcAinA5AmlAatA8Aam.AWhatAwouldAbeAtheAbestAvolume
AtoAbeAwithdrawnAatA10AamAifAaAperfusionAlungAscanAisAplannedA(decayAconstantA=A0.794)A
-AAnswerA0.63Aml
WhatAisAtheAmostAlikelyAsizeAofAanAMAAAparticleAifAcorrectlyAprepared?A-AAnswerA10-30Aµm
99mTcAMAAAhasAaAbiologicalAhalfAlifeAofA2-4Ahrs;AwhatAwillAtheAeffectiveAhalfAlifeAbe?A-
AAnswerA1.5A-A2.4Ahrs
WhichAradiopharmaceuticalAisAmadeAwithA99mTcAwithoutAaAreducingAagent?A-
AAnswerAsulfurAcolloid
WhichAofAtheAfollowingAisAanAexampleAofAradiochemicalAimpurity?
1)ApresenceAofAfreeA99mTcAinAaAprepAofA99mTcAsulfurAcolloid
2)ApresenceAofA99MoAinA99mTcAeluate
3)ApresenceAofAaluminumAionsAinA99mTcAeluate
4)ApresenceAofApyrogensAinAeluateA-
AAnswerA1)ApresenceAofAfreeA99mTcAinAprepAofA99mTcAsulfurAcolloid
WhichAofAtheAfollowingAcanAbeAsaidAregardingAeffectiveAhalf-
life?A1)AItAisAalwaysAlongerAthanAtheAphysicalAhalfAlifeA2)AItAalwaysAshorterAthanAbothAtheA
physicalAandAbiologicalAhalfAlifeA3)AItAisAalwaysAshorterAthanAphysicalAhalfAlifeAbutAlongerAth
anAbiologicalAhalfAlifeA4)ItAisAalwaysAlongerAthanAtheAbiologicalAbutAshorterAthanAtheAphysical
AhalfAlife?A-AAnswerA2
TheApurposeAofAaddingAEDTAAtoAsulfurAcolloidAwhenAlabelingAwithA99mTcAisA-
AAnswerAEDTAAisAaAchelatingAagentAtoApreventAaggregationAofAsulfurAcolloidAandAtoAbindAexc
essAAl3+
AAdiphosphonateAkitAshouldAgenerallyAbeAusedAwithinAhowAmanyAhoursAafterApreparation?A-
AAnswerA4
WhatAisAtheAusualAparticleAsizeAofAsulfurAcolloid?A-AAnswerA0.3A-A1.0Aum
WhichAradiopharmaceuticalAwhenAcorrectlyApreparedAwillAhaveAtheAsmallestAparticleAsize?A-
AAnswerA99mTcAhumanAserumAalbumin
Review Questions for Board
Examinations with 100% Correct
Answers
HowAdoesA201TlAdecay?A-
AAnswerAElectronAcaptureAwithAgammaAemissionsAofA0.135AMeVAandA0.167AMeV
WhatAisAtheAroleAofAtheAstandoutsAionAinAtheApreparationAofApharmaceuticalsAlabeledAwithA99
mTc?A-
AAnswerAStannousAChlorideAisAaAreducingAagentAwhichAchangesAofAvalenceAstateAofATcAinApert
echnetate.AItAhasAnoAeffectAonAeitherAtheAamountAofAAl3+AorAtheAradiationAdose.
IfAanAassayAofAaAvialAcontainingA131IAshowsA50AmCiApresentAonAMayA2,AapproximatelyAwhat
AwillAtheAassayAshowAonAMayA18?A-AAnswerA12.5AmCi
IfAaAboneAscanAhasAbeenAorderedAonAaA5-year-
oldAgirl,AandAtheAphysicianAprescribesA62%AofAtheAadultAdoseAtoAbe
given,AhowAmanyAmCiAshouldAbeAadministered?A-AAnswerA12.4AmCi
IfAtheAbiologicalAhalf-lifeAofAanAisotopeAisA6AhAandAtheAphysicalAhalf-
lifeAisA12Ah,AwhatAisAtheAeffectiveAhalf-life?A-AAnswerA4Ahrs
WhichAofAtheAfollowingAisAusedAtoAabbreviateAphysicalAhalfAlife?A-AAnswerATp
TheAphysicalAhalfAlifeAofAaAradionuclideAisAtheAtimeAitAtakes:A-
AAnswerAforAtheAnuclideAtoAdecayAtoAoneAhalfAofAtheAoriginalAactivity
IfAaAkitAhasA310AmCiAofAactivityApresentAatA8:00Aa.m.,AwhatAwillAtheAvialAassayAshowAinA4
AhAandA10AminAifAtheAdecayAfactorAisA0.618?A-AAnswerA192AmCi
AAvialAcontainingA99mTcAisAassayedAatA9AamAandAcontainsA255AmCi.AToAcalculateAtheAremaini
ngAactivityAatA3ApmAwhatAdecayAfactorAwouldAbeAused?A-AAnswerA0.5
AAvialAofAtechnetiumAeluateAcontainsA50AmCi/ml.AIfA4AmlAis
,withdrawnAandAaddedAtoAaAdiphosphonateAkitAcontaining
16AmlAofAsolution,AwhatAvolumeAwouldAthenAneedAtoAbe
withdrawnAtoAprepareAaA20AmCiAdoseAatAthatAmoment?A-AAnswerA2
IfAaApreparationAofA99mTcAmertiatideAhasA60AmCiAofAactivityApresentAatA8:30Aam,AhowAmany
AmCiAwillAbeApresentAatA9Aam?A(DecayAconstantA=A0.944)A-AAnswerA56.6
WhichAofAtheAfollowingAisAboiledAduringApreparation?A-AAnswerAsulfurAcolloid
TheApresenceAofA12AugAAl+3AinA1AmlAofA99mTcAeluateAisA-
AAnswerAChemicalAimpurity;AAlA3+AionsAfromAtheAaluminaAcolumnAofAtheAmustAbeAlessAthanA
10AugAAl3+/mlAofAeluateA-AthisAlimitAisAsetAbyAUSAPharmacopoeia
WhichAbodyAdecidesAonAtheAacceptableAlevelsAofAradionuclidicAimpurity?A-AAnswerANRCA&AUSP
WhichAofAtheAfollowingAisAanAexampleAofAradionuclidicAimpurity:
1)ApresenceAofAfreeA99mTcAinAaApreparationAofA99mTcAsulfurAcolloid
2)APresenceAofA99MoAinA99mTcAeluate
3)ApresenceAofAaluminumAionsAinA99mTcAeluate
4)ApresenceAofApyrogensAinAeluateA-AAnswerA2
WhatAisAtheAmaximumAamountAofAaluminumAionsA(AL3+)AallowedAinAoneAmilliliterAofA99mTcAe
luateAaccordingAtoAtheAUSP?A-AAnswerA10Aμg
WhatAisAindicatedAbyAtheAfrontAofAanAITLCAstrip?A-
AAnswerAThisAdependsAonAtheAsolventAandAstripAused
IfAaAkitAcontainsA140AmCiAofA99mTcAinA23Aml,AhowAmuchAvolumeAmustAbeAwithdrawnAtoAob
tainAaAdoseAofA5AmCi?A-AAnswerA0.8AmLA-
AspecificAconcentrationAisA140AmCi/23AmlAorA6.1AmCi/ml
IfAaAkitAcontainsA140AmCiAofA99mTcAinA23AmlAatA9:00Aa.m.,AhowAmuchAvolumeAmustAbeAwi
thdrawnAtoAobtainAaAdoseAofA5AmCiAatA3:00Ap.m.?A-AAnswerA1.6Aml
, AnAMAAAkitAcontainsA40AmCiAofA99mTcAinA5AmlAatA8Aam.AWhatAwouldAbeAtheAbestAvolume
AtoAbeAwithdrawnAatA10AamAifAaAperfusionAlungAscanAisAplannedA(decayAconstantA=A0.794)A
-AAnswerA0.63Aml
WhatAisAtheAmostAlikelyAsizeAofAanAMAAAparticleAifAcorrectlyAprepared?A-AAnswerA10-30Aµm
99mTcAMAAAhasAaAbiologicalAhalfAlifeAofA2-4Ahrs;AwhatAwillAtheAeffectiveAhalfAlifeAbe?A-
AAnswerA1.5A-A2.4Ahrs
WhichAradiopharmaceuticalAisAmadeAwithA99mTcAwithoutAaAreducingAagent?A-
AAnswerAsulfurAcolloid
WhichAofAtheAfollowingAisAanAexampleAofAradiochemicalAimpurity?
1)ApresenceAofAfreeA99mTcAinAaAprepAofA99mTcAsulfurAcolloid
2)ApresenceAofA99MoAinA99mTcAeluate
3)ApresenceAofAaluminumAionsAinA99mTcAeluate
4)ApresenceAofApyrogensAinAeluateA-
AAnswerA1)ApresenceAofAfreeA99mTcAinAprepAofA99mTcAsulfurAcolloid
WhichAofAtheAfollowingAcanAbeAsaidAregardingAeffectiveAhalf-
life?A1)AItAisAalwaysAlongerAthanAtheAphysicalAhalfAlifeA2)AItAalwaysAshorterAthanAbothAtheA
physicalAandAbiologicalAhalfAlifeA3)AItAisAalwaysAshorterAthanAphysicalAhalfAlifeAbutAlongerAth
anAbiologicalAhalfAlifeA4)ItAisAalwaysAlongerAthanAtheAbiologicalAbutAshorterAthanAtheAphysical
AhalfAlife?A-AAnswerA2
TheApurposeAofAaddingAEDTAAtoAsulfurAcolloidAwhenAlabelingAwithA99mTcAisA-
AAnswerAEDTAAisAaAchelatingAagentAtoApreventAaggregationAofAsulfurAcolloidAandAtoAbindAexc
essAAl3+
AAdiphosphonateAkitAshouldAgenerallyAbeAusedAwithinAhowAmanyAhoursAafterApreparation?A-
AAnswerA4
WhatAisAtheAusualAparticleAsizeAofAsulfurAcolloid?A-AAnswerA0.3A-A1.0Aum
WhichAradiopharmaceuticalAwhenAcorrectlyApreparedAwillAhaveAtheAsmallestAparticleAsize?A-
AAnswerA99mTcAhumanAserumAalbumin
