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HESI RN Exit Exam 2 Comprehensive Study Guide Nursing Review 2026 complete exam preparation material

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This comprehensive study guide covers key nursing topics for the HESI RN Exit Exam, including gastrointestinal, cardiovascular, respiratory, neurological, pharmacology, maternity, pediatrics, and geriatric care. It includes prioritized questions with detailed rationales focused on clinical decision-making, patient safety, and NCLEX-style critical thinking. The material is structured into multiple sections to reinforce core nursing concepts such as emergency interventions, medication management, delegation, and ethical practice. It is ideal for final exam preparation and review of high-yield concepts frequently tested on the HESI RN exit exam.

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HESI RN EXIT EXAM 2
COMPREHENSIVE
STUDY GUIDE

SECTION 1: GASTROINTESTINAL & HEPATIC



QUESTION 1

Client with acute pancreatitis admitted. Which assessment has highest priority?

ANSWER

D. Intensity of pain

RATIONALE / EXPLANATION

Hallmark sign of pancreatitis is severe abdominal pain due to autodigestion of pancreas by
amylase and lipase.



QUESTION 2

Ascites related to liver failure - which pathophysiological mechanisms? (Select all)

ANSWER

B. Fluid shifts due to decreased serum protein
C. Increased hydrostatic pressure in portal circulation
D. Increased aldosterone levels increase sodium/water retention

RATIONALE / EXPLANATION

Liver failure: decreased albumin → fluid shifts; portal hypertension → fluid into abdomen;
aldosterone not inactivated → retention.



QUESTION 3

Clinical finding in cardiac cirrhosis?

ANSWER

C. Peripheral edema

RATIONALE / EXPLANATION

Page 1 of 28

,Cardiac cirrhosis is associated with severe right-sided HF - peripheral edema is the most defining
characteristic.



QUESTION 4

Client had abdominal surgery yesterday. Wound edges close together, no redness, slight
bright red oozing. Action?

ANSWER

A. Record these findings in the client's record

RATIONALE / EXPLANATION

These are NORMAL findings for one day postoperative - wound healing by primary intention.




Page 2 of 28

, SECTION 2: CARDIOVASCULAR & EMERGENCY



QUESTION 5

Heart failure client's lower extremities swell when sitting at computer all day. Best response?

ANSWER

C. Get up and walk around frequently during the day

RATIONALE / EXPLANATION

Walking stimulates circulation, venous return, and reduces swelling from gravitational blood
pooling.



QUESTION 6

50-year-old with cocaine ingestion has VT converting to VF. Priority action?

ANSWER

B. Defibrillate at 200 joules

RATIONALE / EXPLANATION

Rapid defibrillation is critical to re-establish cardiac output and preserve vital organ function.



QUESTION 7

EKG waveform analysis - what indicates disturbance in ventricular electrical conduction?

ANSWER

QRS interval of 0.14 seconds

RATIONALE / EXPLANATION

Normal QRS is 0.04-0.12 seconds. Prolonged QRS (>0.12) indicates ventricular electrical
anomaly.



QUESTION 8

Calculate MAP for BP 152/90 mm Hg:

ANSWER

Page 3 of 28

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