WGU D027 Advanced Pathopharmacological
Foundations Objective Assessment, Western
Governors University, 2026/2027 –Question
MSN-Aligned Practice Exam with Verified
Solutions
What organ does cystic fibrosis affect? - ANSWERS-Affects the pancreas
causing secretions into the lungs
What is Klinefelter syndrome? - ANSWERS-An extra X chromosome for males
so example XXY causing female-like qualities
What is Turner Syndrome? - ANSWERS-females. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection,
language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - ANSWERS-a condition in which the synthesis of
the beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? -
ANSWERS-Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue
(leukemia). Directly toxic to lymphoid tissues Selective estrogen receptor
modulators (SERM) - for hormone receptor positive and advanced breast
cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWERS-
Glucocorticoids
, What is the normal ejection fraction? - ANSWERS-55-60%. Less than 50% is
BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWERS-Preserved
What are symptoms of left sided heart failure? - ANSWERS-Think
PULMONARY. JVD, FVO, rails, S3 murmurs. Number one cause of right sided
heart failure!
What are symptoms of right sided heart failure? - ANSWERS-Think peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWERS-BNP. Heart
failure is a result greater than 100
What heart disease is worse with exertion? - ANSWERS-Ischemic heart
disease because the demand requirements are higher.
What should you assess before giving Digoxin? - ANSWERS-Apical pulse
How should Warfarin be started? - ANSWERS-Start initial dose at half to
monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out
which leads to hyperinflation - ANSWERS-Emphysema
What causes excess mucus production and smooth muscle hypertrophy? -
ANSWERS-Bronchitis
Foundations Objective Assessment, Western
Governors University, 2026/2027 –Question
MSN-Aligned Practice Exam with Verified
Solutions
What organ does cystic fibrosis affect? - ANSWERS-Affects the pancreas
causing secretions into the lungs
What is Klinefelter syndrome? - ANSWERS-An extra X chromosome for males
so example XXY causing female-like qualities
What is Turner Syndrome? - ANSWERS-females. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection,
language and articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - ANSWERS-a condition in which the synthesis of
the beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? -
ANSWERS-Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue
(leukemia). Directly toxic to lymphoid tissues Selective estrogen receptor
modulators (SERM) - for hormone receptor positive and advanced breast
cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWERS-
Glucocorticoids
, What is the normal ejection fraction? - ANSWERS-55-60%. Less than 50% is
BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWERS-Preserved
What are symptoms of left sided heart failure? - ANSWERS-Think
PULMONARY. JVD, FVO, rails, S3 murmurs. Number one cause of right sided
heart failure!
What are symptoms of right sided heart failure? - ANSWERS-Think peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWERS-BNP. Heart
failure is a result greater than 100
What heart disease is worse with exertion? - ANSWERS-Ischemic heart
disease because the demand requirements are higher.
What should you assess before giving Digoxin? - ANSWERS-Apical pulse
How should Warfarin be started? - ANSWERS-Start initial dose at half to
monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out
which leads to hyperinflation - ANSWERS-Emphysema
What causes excess mucus production and smooth muscle hypertrophy? -
ANSWERS-Bronchitis
