PHARMACOTHERAPEUCITS
1. Tocolytic agents are used to :
(a) Enhance the preterm labor
(b) Suppress the preterm labor
(c) Enhance the normal labor
(d) Suppress the normal labor [b]
Exp. :–
– Any agent that diminishes uterine contractions by reducing myometrial excitability called
tocolytic agents. Its use to stop premature labour, e.g. ritodrine, terbutaline, isoxsuprine etc.
2. Complication of tocolytic agent is
(a) Uterine rupture
(b) Hyperstimulation of uterus
(c) Increased peristaltic movement
(d) Pulmonary edema [d]
3. While administering oxytocin infusion in a term pregnant woman, what rate should not
be exceeded because it is likely to cause tetanic contractions?
(a) 2 milliunits/min
(b) 4 milliunits/min
(c) 16 milliunits/min
(d) 20 milliunits/min [c]
Exp. :–
– In majority of cases a dose of less than 16mIU/min (it achieve by mixing 2 unit oxytocin in
500ml RL at 60/min drop rate) is enough to achieve its objective of administration.
4. Which of these drugs is contraindicated in a labouring mother with hypertension?
(a) Oxytocin
(b) Prostaglandins
(c) Methergine
(d) Magnesium sulphate [c]
Exp. :–
– Methyl - ergometrine (methergine) is contraindicated in peripheral vascular disease, heart
disease & hypertension
5. In which patients Methyl ergometrine is contraindicated?
(a) Heart disease
(b) Lung disease
(c) Liver disease
(d) Kidney disease [a]
6. The importance of prostaglandins in onset of labour is to
(a) Stimulate expulsion of fetus
(b) Stimulate uterine muscle activity
(c) Reduce uterine muscle activity
(d) Help in the placental expulsion [b]
Exp. :–
– Prostaglandins are a large group of "local hormone" produced by the metabolism of an
essential fatty acid arachidonic acid. Its use into obstetric are induction & augmentation of
labor or abortion, ripening & softening of cervix (e.g. PGE2), increase contraction of uterine
muscles and management of atonic PPH.
1. Tocolytic agents are used to :
(a) Enhance the preterm labor
(b) Suppress the preterm labor
(c) Enhance the normal labor
(d) Suppress the normal labor [b]
Exp. :–
– Any agent that diminishes uterine contractions by reducing myometrial excitability called
tocolytic agents. Its use to stop premature labour, e.g. ritodrine, terbutaline, isoxsuprine etc.
2. Complication of tocolytic agent is
(a) Uterine rupture
(b) Hyperstimulation of uterus
(c) Increased peristaltic movement
(d) Pulmonary edema [d]
3. While administering oxytocin infusion in a term pregnant woman, what rate should not
be exceeded because it is likely to cause tetanic contractions?
(a) 2 milliunits/min
(b) 4 milliunits/min
(c) 16 milliunits/min
(d) 20 milliunits/min [c]
Exp. :–
– In majority of cases a dose of less than 16mIU/min (it achieve by mixing 2 unit oxytocin in
500ml RL at 60/min drop rate) is enough to achieve its objective of administration.
4. Which of these drugs is contraindicated in a labouring mother with hypertension?
(a) Oxytocin
(b) Prostaglandins
(c) Methergine
(d) Magnesium sulphate [c]
Exp. :–
– Methyl - ergometrine (methergine) is contraindicated in peripheral vascular disease, heart
disease & hypertension
5. In which patients Methyl ergometrine is contraindicated?
(a) Heart disease
(b) Lung disease
(c) Liver disease
(d) Kidney disease [a]
6. The importance of prostaglandins in onset of labour is to
(a) Stimulate expulsion of fetus
(b) Stimulate uterine muscle activity
(c) Reduce uterine muscle activity
(d) Help in the placental expulsion [b]
Exp. :–
– Prostaglandins are a large group of "local hormone" produced by the metabolism of an
essential fatty acid arachidonic acid. Its use into obstetric are induction & augmentation of
labor or abortion, ripening & softening of cervix (e.g. PGE2), increase contraction of uterine
muscles and management of atonic PPH.
