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NR565 Week 8 Final Exam Study Guide | Advanced Pharmacology | 150+ Q&A

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Complete NR565 Week 8 final exam study guide for advanced pharmacology. Includes 150+ high-yield practice questions with detailed rationales covering thyroid disorders (hypothyroidism, hyperthyroidism, levothyroxine, methimazole), diabetes management (metformin, GLP-1 agonists, insulin, sulfonylureas, SGLT2 inhibitors, TZDs, DPP-4 inhibitors), respiratory pharmacology (asthma step therapy, COPD, albuterol, salmeterol, ICS, roflumilast), cardiovascular pharmacology (hypertension, ACE inhibitors, ARBs, thiazides, statins, warfarin, heparin), substance use disorders (buprenorphine, naloxone, alcohol withdrawal, disulfiram, naltrexone), immunizations (live vs inactivated vaccines), GI/rheumatology (antacids, PPIs, DMARDs, methotrexate), and dermatology (permethrin, tretinoin). Includes NGN case studies (uncontrolled diabetes, asthma, thyroid storm, hypertension). Based on Chamberlain University NR565 course. Perfect for NP students.

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NR565 WEEK 8 FINAL EXAM STUDY GUIDE:
ADVANCED PHARMACOLOGY FUNDAMENTALS
COMPLETE PRACTICE EXAMINATION | 150+
HIGH-YIELD QUESTIONS WITH DETAILED
RATIONALES | BASED ON CHAMBERLAIN
UNIVERSITY NR565 COURSE | 2026-2027
EDITION



Table of Contents


| Module | Topic Area | Questions |
| 1 | Thyroid Disorders (Hypothyroidism, Hyperthyroidism) | 15 |
| 2 | Diabetes Mellitus Management | 20 |
| 3 | Respiratory Pharmacology (Asthma, COPD) | 15 |
| 4 | Cardiovascular Pharmacology & Hypertension | 20 |
| 5 | Substance Use Disorders & Pain Management | 10 |
| 6 | Immunizations & Infectious Diseases | 10 |
| 7 | Gastrointestinal & Rheumatologic Disorders | 10 |
| 8 | Dermatologic & Topical Agents | 10 |
| 9 | NGN/Clinical Case Studies | 15 |

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# Section 1: Thyroid Disorders (15 Questions)


**Question 1.**
A patient has a TSH of 0.28 mIU/L, free T4 of 3.0 ng/dL, and free T3
over 650 pg/dL. Which medication should she be started on?


A) Levothyroxine
B) Methimazole or PTU
C) Liothyronine
D) Propranolol only


**Answer:** B) Methimazole or PTU
**Rationale:** Low TSH with elevated free T4 and T3 indicates
hyperthyroidism. Treatment options include methimazole,
propylthiouracil (PTU), or radioactive iodine. Beta-blockers
(propranolol) are used for symptom control but do not treat the
underlying hyperthyroidism.


---


**Question 2.**
What does a low level of thyroid-stimulating hormone (TSH) indicate?

,3|Page




A) Hypothyroidism
B) Hyperthyroidism
C) Euthyroid state
D) Thyroiditis


**Answer:** B) Hyperthyroidism
**Rationale:** Low TSH with normal/high T4 indicates
hyperthyroidism. TSH is suppressed when thyroid hormone levels are
elevated due to negative feedback on the anterior pituitary.


---


**Question 3.**
When should TSH levels be rechecked after initiating levothyroxine
therapy?


A) 2 weeks
B) 4 weeks
C) 6-8 weeks
D) 3 months


**Answer:** C) 6-8 weeks

, 4|Page


**Rationale:** TSH should be rechecked 6-8 weeks after initiating
therapy and after any dosage change. Once stabilized, check TSH at
least once a year.


---


**Question 4.**
Which of the following are signs and symptoms of hyperthyroidism?
(Select all that apply)


□ Bradycardia and cold intolerance
□ Tachycardia and palpitations
□ Weight loss with increased appetite
□ Lethargy and fatigue
□ Heat intolerance and warm, moist skin
□ Exophthalmos (in Graves' disease)


**Answer:** Tachycardia and palpitations, Weight loss with increased
appetite, Heat intolerance and warm, moist skin, Exophthalmos
**Rationale:** Hyperthyroidism causes increased metabolic rate:
tachycardia, weight loss despite increased appetite, heat intolerance,
warm moist skin, nervousness, tremors, and exophthalmos in Graves'
disease. Bradycardia, cold intolerance, and lethargy are signs of
hypothyroidism.

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