WINTER 2026/2027 | 100% Correct Answer Guide | Pass
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Section 1: Infection Control & Prevention (Questions 1-10)
Q1. A nurse enters a patient's room to administer morning medications. According to
CDC 2026 hand hygiene guidelines and the WHO 5 Moments, when should the nurse
perform hand hygiene?
A. Only before touching the patient [INCORRECT] - This misses critical moments
including after touching the patient and after touching the patient's surroundings.
B. Before touching the patient, before aseptic procedures, after body fluid exposure
risk, after touching the patient, and after touching patient surroundings [CORRECT] -
This is the complete WHO 5 Moments for Hand Hygiene. All five moments are
required for comprehensive infection prevention per CDC 2026 guidelines.
C. Only after removing gloves at the end of the encounter [INCORRECT] - Hand
hygiene is required at multiple points during patient care, not just at the end.
D. Only when hands are visibly soiled [INCORRECT] - Hand hygiene is required even
when hands are not visibly soiled, as pathogens are not visible to the naked eye.
Rationale: The WHO 5 Moments for Hand Hygiene are the gold standard: (1) before
touching a patient, (2) before clean/aseptic procedures, (3) after body fluid exposure
risk, (4) after touching a patient, (5) after touching patient surroundings. CDC 2026
guidelines affirm these moments as the foundation of standard precautions.
Correct Answer: B
,Q2. A patient is diagnosed with Clostridioides difficile (C. diff) infection. Which hand
hygiene and environmental cleaning protocol is CORRECT per 2026 CDC guidelines?
A. Use alcohol-based hand rub (ABHR) for hand hygiene and standard disinfectant
wipes for room cleaning [INCORRECT] - C. diff is a spore-forming organism. ABHR is
ineffective against spores; soap and water must be used.
B. Use soap and water for hand hygiene and bleach-based (EPA-registered sporicidal)
disinfectant for environmental cleaning [CORRECT] - C. diff spores are resistant to
alcohol. Soap and water with mechanical friction removes spores from hands. Bleach-
based disinfectants are required for environmental cleaning to kill spores.
C. Use ABHR for hand hygiene and standard quaternary ammonium disinfectant for
room cleaning [INCORRECT] - Both ABHR and standard disinfectants are ineffective
against C. diff spores.
D. No special precautions needed; C. diff is part of normal flora [INCORRECT] - C.
diff infection requires contact precautions, special hand hygiene, and sporicidal
environmental cleaning.
Rationale: C. diff is a spore-forming organism requiring specific protocols: soap and
water hand hygiene (ABHR is ineffective against spores) and EPA-registered
sporicidal disinfectants (bleach-based) for environmental cleaning. This is a critical
distinction in infection control.
Correct Answer: B
Q3. A healthcare worker is preparing to enter the room of a patient with suspected
tuberculosis. Which PPE sequence is CORRECT for donning?
A. Gloves → Gown → N95 respirator → Eye protection [INCORRECT] - Gloves should
be donned last, not first. This sequence risks contamination of gloves during gown
donning.
B. Gown → N95 respirator → Eye protection → Gloves [CORRECT] - The correct
donning sequence is: (1) gown, (2) respirator/mask, (3) eye protection, (4) gloves.
Gloves are last to ensure they cover gown cuffs.
,C. N95 respirator → Gloves → Gown → Eye protection [INCORRECT] - Gloves are
donned too early and would become contaminated during gown and eye protection
application.
D. Eye protection → Gown → Gloves → N95 respirator [INCORRECT] - Respirator
should be donned before eye protection to ensure proper fit testing and seal check.
Rationale: CDC standard PPE donning sequence: gown first, then respirator/mask,
then eye/face protection, then gloves last. Gloves must cover gown cuffs. For
airborne precautions (TB), an N95 or higher-level respirator is required instead of a
standard surgical mask.
Correct Answer: B
Q4. A nurse is leaving the room of a patient on Contact Precautions for MRSA. Which
doffing sequence is CORRECT?
A. Remove gloves → Remove gown → Remove mask → Perform hand hygiene
[INCORRECT] - Gloves should not be removed first; gown removal would
contaminate bare hands.
B. Remove gown and gloves together (gloves inside-out over gown), then remove
eye protection, then remove mask, then perform hand hygiene [CORRECT] - The
correct doffing sequence removes the most contaminated items first while protecting
clean areas. Gown and gloves are removed together, then eye protection, then mask,
followed by hand hygiene.
C. Remove mask first, then gloves, then gown, then perform hand hygiene
[INCORRECT] - Mask should be removed last (or after eye protection) to prevent
contamination of the respiratory tract during doffing.
D. Remove eye protection first, then gloves, then gown, then mask, then hand
hygiene [INCORRECT] - While eye protection can be removed early, gloves should
be removed with the gown to prevent contamination.
Rationale: CDC doffing sequence: (1) remove gown and gloves together (gloved
hands only touch contaminated surfaces), (2) remove face shield/goggles, (3) remove
, mask/respirator, (4) perform hand hygiene. This prevents self-contamination during
PPE removal.
Correct Answer: B
Q5. Which of the following situations requires the use of soap and water instead of
alcohol-based hand rub (ABHR)? (Select all that apply)
A. After caring for a patient with C. diff infection [CORRECT] - ABHR is ineffective
against C. diff spores. Soap and water with mechanical friction is required.
B. After removing gloves following a blood draw from a patient with hepatitis B
[INCORRECT] - ABHR is effective against enveloped viruses including HBV. Soap and
water is not specifically required.
C. When hands are visibly soiled with blood or body fluids [CORRECT] - ABHR is less
effective when hands are visibly soiled. Soap and water is required for visible
contamination.
D. Before inserting a peripheral IV catheter [INCORRECT] - ABHR is appropriate
before aseptic procedures when hands are not visibly soiled.
E. After using the restroom [CORRECT] - Soap and water is required after using the
restroom per standard hygiene practices, regardless of patient care context.
Rationale: Soap and water is required when hands are visibly soiled, after caring for
patients with C. diff or other spore-forming organisms, after using the restroom, and
before eating. ABHR is appropriate for all other standard hand hygiene moments.
Correct Answers: A, C, E
Q6. A sharps container in the medication room is filled to the 3/4 mark. What is the
CORRECT action per OSHA Bloodborne Pathogens Standard?