Chapter Essentials
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Chapter 1 Drug Regulation
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Pharmacology Essentials
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Chapter 1 Drug Regulation Actions and Responses Pharmacology
Chapter Essentials
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,Understanding Pharmacology Essentials for Medication Safety_ Chapter Understanding
1_ Drug Regulation,
Pharmacology
Actions, and
Essentials
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for Medication Safety_ Chapter Understanding
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Pharmacology
Actions, and
Essentials
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Terms in this set (310)
Adbsorption Movement of a drug from the outside of the body into the bloodstream
Adverse Drug Reaction (ADR) Same as Adverse Effect
Adverse Effect A drug effect that is more severe than expected and has the potential to damage
tissue or cause serious health problems.
It may also be called a toxic effect or toxicity and usually requires intervention by the
prescriber
Agonist An extrinsic drug that activates the receptor site of a cell and mimics the actions of
naturally occurring body substances (intrinsic drugs)
Allergic Response Type of adverse effect in which the presence of the drug stimulates the release of
histamine and other body chemicals that cause inflammatory reactions.
The response may be as mild as a rash or as severe and life threatening as
anaphylaxis
Antagonist An extrinsic drug that blocks the receptor site of a cell, preventing the naturally
occuring body substance from binding to the receptor
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Pharmacology
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Bioavailability The percentage of a drug dose that actually reaches the blood
Black Box Warning A notice that a drug may produce serious or even life-threatening effect in some
people in addition to its beneficial effects
Brand Name A manufacturer-owned name of generic drug;
Also called "trade name" or "proprietary name"
Contraindication A personal or health-related reason for not administering a specific drug to a patient
or a group of patients
Cytotoxic Drug action that is intended to kill a cell or an organism
Distribution (Drug Distribution)
The extent that a drug absorbed into the bloodstream spreads into the three body
water compartments
Drug Any small molecule that changes any body function by working at the chemical and
cell levels
Drug Therapy The planned use of a drug to prevent or improve a health problem
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Duration of Action The length of time a drug is present in the blood at or above the level needed to
prodice an effect or response
Elimination The removal of drugs from the body accomplished by certain body systems
Enteral Route Movememnt of drugs from the outside of the body to the inside using the
gastrointestinal tract
First-Pass Loss Rapid inactivation or elimination of oral drugs as a result of liver metabolism
Generic Name National and international public drug name created by the United States Adopted
Names (USAN) Council to indicate the usual use or chemical composition of a drug
USAN United States Adopted Names
Half-Life Time span needed for one half of a drug dose to be eliminated
High-Alert Drug A drug that has an increased risk for causing patient harm if it us used in error
Intended Action Desired Effect (main effect) of a drug on a specific body cells or tissues;
Same as Therapeutic Response
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