ACVPM PrACtiCe test exAM 2026/2027 – OffiCiAl BluePrint
rePliCA with DetAileD rAtiOnAles | rAnDOM QuestiOn OrDer |
PAss GuArAnteeD – A+ GrADeD
Question 1
A study examines the relationship between feeding raw meat and Salmonella infection in dogs. The odds
ratio (OR) is 4.2 with a 95% confidence interval (CI) of 1.8 to 9.6. Which of the following statements is
correct?
A. The result is not statistically significant because the CI includes 1.0
B. The result is statistically significant because the CI does not include 1.0
C. The OR of 4.2 means the risk of infection is exactly 4.2 times higher in exposed dogs
D. The wide CI indicates that the study had very high precision
Answer: B
Rationale: A 95% CI that does not include 1.0 indicates statistical significance at alpha=0.05. An OR
approximates relative risk only when disease is rare; it does not directly equal risk ratio (C). A wide CI
indicates low precision, not high (D).
Question 2
A screening test for bovine tuberculosis has a sensitivity of 90% and specificity of 96%. In a herd with a
true prevalence of 5%, what is the positive predictive value (PPV)?
A. 90%
B. 54%
C. 96%
D. 32%
Answer: B
, Rationale: PPV = (sensitivity x prevalence) / [sensitivity x prevalence + (1-specificity) x (1-prevalence)].
Calculate: (0.90 x 0.05) = 0.045; denominator = 0.045 + (0.04 x 0.95) = 0.045 + 0.038 = 0.083; PPV =
0.045/0.083 = 0.542 or 54.2%.
Question 3
Which of the following zoonotic diseases is most frequently associated with handling aborted fetal tissues
from sheep and goats?
A. Anthrax
B. Q fever (Coxiella burnetii)
C. Brucellosis (Brucella abortus)
D. Leptospirosis
Answer: B
Rationale: Q fever is highly associated with parturient fluids and placentas of sheep, goats, and cattle.
The causative agent Coxiella burnetii is extremely infectious via aerosol. Brucella melitensis (goats) and
B. abortus (cattle) are also zoonotic but less commonly highlighted for this scenario in exam contexts.
Question 4
In a population of 2,000 cattle, 500 are vaccinated against bovine viral diarrhea (BVD). During an
outbreak, 50 vaccinated cattle and 600 unvaccinated cattle develop disease. What is the vaccine
effectiveness (VE) under field conditions?
A. 60%
B. 75%
C. 80%
D. 67%
Answer: D
rePliCA with DetAileD rAtiOnAles | rAnDOM QuestiOn OrDer |
PAss GuArAnteeD – A+ GrADeD
Question 1
A study examines the relationship between feeding raw meat and Salmonella infection in dogs. The odds
ratio (OR) is 4.2 with a 95% confidence interval (CI) of 1.8 to 9.6. Which of the following statements is
correct?
A. The result is not statistically significant because the CI includes 1.0
B. The result is statistically significant because the CI does not include 1.0
C. The OR of 4.2 means the risk of infection is exactly 4.2 times higher in exposed dogs
D. The wide CI indicates that the study had very high precision
Answer: B
Rationale: A 95% CI that does not include 1.0 indicates statistical significance at alpha=0.05. An OR
approximates relative risk only when disease is rare; it does not directly equal risk ratio (C). A wide CI
indicates low precision, not high (D).
Question 2
A screening test for bovine tuberculosis has a sensitivity of 90% and specificity of 96%. In a herd with a
true prevalence of 5%, what is the positive predictive value (PPV)?
A. 90%
B. 54%
C. 96%
D. 32%
Answer: B
, Rationale: PPV = (sensitivity x prevalence) / [sensitivity x prevalence + (1-specificity) x (1-prevalence)].
Calculate: (0.90 x 0.05) = 0.045; denominator = 0.045 + (0.04 x 0.95) = 0.045 + 0.038 = 0.083; PPV =
0.045/0.083 = 0.542 or 54.2%.
Question 3
Which of the following zoonotic diseases is most frequently associated with handling aborted fetal tissues
from sheep and goats?
A. Anthrax
B. Q fever (Coxiella burnetii)
C. Brucellosis (Brucella abortus)
D. Leptospirosis
Answer: B
Rationale: Q fever is highly associated with parturient fluids and placentas of sheep, goats, and cattle.
The causative agent Coxiella burnetii is extremely infectious via aerosol. Brucella melitensis (goats) and
B. abortus (cattle) are also zoonotic but less commonly highlighted for this scenario in exam contexts.
Question 4
In a population of 2,000 cattle, 500 are vaccinated against bovine viral diarrhea (BVD). During an
outbreak, 50 vaccinated cattle and 600 unvaccinated cattle develop disease. What is the vaccine
effectiveness (VE) under field conditions?
A. 60%
B. 75%
C. 80%
D. 67%
Answer: D
