NAPSRX CNPR EXAM (REVISED 18TH EDITION)
QUESTIONS WITH RIGHT ANSWERS .
what does a STAT order mean? - Correct Answer -a drug needed immediately and given only
once
what information does the overdosage section of the labeling provide? - Correct Answer -
signs, symptoms and treatment of acute overdoses
types of drug-drug interactions: - Correct Answer -duplication, opposition (antagonism) and
alteration (p.51)
tolerance vs resistance - Correct Answer -tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - Correct Answer -the process by which
applicants must scientifically demonstrate to the FDA that their generic product is
bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p.
75)
the Hatch-Waxman Act of 1984 - Correct Answer --A.K.A. Drug Price Competition and
Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at
bioavailability studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic
cooling off period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - Correct Answer -passive diffusion, facilitated diffusion,
active transport, and pinocytosis (p. 95)
potency vs efficacy - Correct Answer -potency: amount of drug necessary to produce desired
effect
efficacy: magnitude of maximal response that can be received from a drug
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, *efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - Correct Answer -phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - Correct Answer -Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - Correct Answer -reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - Correct Answer -sampling error is unbiased and is
randomly chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics
(p.142-143)
independent vs dependent variable - Correct Answer -An independent variable is the one that
influences the variation. A dependent variable is the variable being tested and measured in a
scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - Correct Answer --involve retrospective
monitoring of physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
opportunity cost - Correct Answer -based on the premise that all resources are scarce, and
therefore every time we choose to use a resource it reduces the possibility of it being used in
another way.
what type of DTC advertising is the only legal form in Europe? - Correct Answer -Disease-
state or unbranded ads (provides public information on a disease, not a drug)
(p. 223)
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QUESTIONS WITH RIGHT ANSWERS .
what does a STAT order mean? - Correct Answer -a drug needed immediately and given only
once
what information does the overdosage section of the labeling provide? - Correct Answer -
signs, symptoms and treatment of acute overdoses
types of drug-drug interactions: - Correct Answer -duplication, opposition (antagonism) and
alteration (p.51)
tolerance vs resistance - Correct Answer -tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - Correct Answer -the process by which
applicants must scientifically demonstrate to the FDA that their generic product is
bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p.
75)
the Hatch-Waxman Act of 1984 - Correct Answer --A.K.A. Drug Price Competition and
Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at
bioavailability studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic
cooling off period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - Correct Answer -passive diffusion, facilitated diffusion,
active transport, and pinocytosis (p. 95)
potency vs efficacy - Correct Answer -potency: amount of drug necessary to produce desired
effect
efficacy: magnitude of maximal response that can be received from a drug
1
, *efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - Correct Answer -phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - Correct Answer -Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - Correct Answer -reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - Correct Answer -sampling error is unbiased and is
randomly chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics
(p.142-143)
independent vs dependent variable - Correct Answer -An independent variable is the one that
influences the variation. A dependent variable is the variable being tested and measured in a
scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - Correct Answer --involve retrospective
monitoring of physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)
opportunity cost - Correct Answer -based on the premise that all resources are scarce, and
therefore every time we choose to use a resource it reduces the possibility of it being used in
another way.
what type of DTC advertising is the only legal form in Europe? - Correct Answer -Disease-
state or unbranded ads (provides public information on a disease, not a drug)
(p. 223)
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