PSYCHOPHARMACOLOGY REVIEW
SHEET TEST 3 2026 FULL
QUESTIONS AND ACCURATE
ANSWERS
◉ Allodynia. Answer: Pain due to a stimulus that does not normally
provoke pain
◉ Hyperalgesia. Answer: Increased pain from a stimulus that normally
provokes pain
◉ Nocioceptive pain. Answer: Pain that arises from actual or threatened
damage to non-neural tissue and is due to the aciviation of .....
◉ Neuropathic pain. Answer: Pain created by a lesion or disease of the
somatosensory nervous system
◉ Central Sensitization. Answer: Increased responsiveness of
nocioceptive neurons in the CNS to their normal or subthreshold afferent
input.
◉ Nocioceptor. Answer: A primary afferent (sensory) neuron that is
only activated by a noxious stimulus
,◉ Nocioception. Answer: The process by which a nocioceptor detects a
noxious stimulus and generates a signal (action potentials) that is
propagated towards higher centers in the nocioceptive pathway
◉ Dorsal Root Ganglion (DRG). Answer: Contains the cell bodies of
primary afferent neurons, proteins, including transmitters, receptors, and
structural proteins, are synthesized here and transported to peripheral
and central terminals.
◉ Interneurons. Answer: Neuron in the dorsal horn that receives input
from PANS and/ or interneurons, and projects up the spinal cord to
higher processing centers
◉ Spinothalamic tract. Answer: tract of neurons that project from the
spinal cord to the thalamus
◉ Spinobulbar tracts. Answer: Several different tracts of neurons that
project from the spinal cord to brainstem nuclei
◉ Somatosensory cortex. Answer: Region of the cerebral cortex that
receives input mainly from cutaneous sensory nerves; the cortex is
topographically arranged, with adjacent areas receiving input from
adjacent body areas; stimulation of the somatosensory cortex creates
sensations from the body part that projects to it.
◉ A-Beta fibers. Answer: detect small movements, light touch
, ◉ A-Delta fibers. Answer: sense noxious mechanical stimuli and
subnoxious thermalstimuli
◉ C-fibers. Answer: bare nerve endings that are only activated by
noxious mechanical, thermal, or chemical stimuli
◉ Describe Neuropathic Pain. Answer: pain that arises from damage to,
or dysfunction of, any part of the peripheral or central nervous system
◉ Describe normal pain. Answer: pain caused by activation of
nociceptive nerve fibers
◉ What is Peripheral Nociceptive Pain due to?. Answer: Inflammation
or mechanical damage in tissues
◉ What does Peripheral Nociceptive pain respond to. Answer: NSAIDS,
opioids, procedures
◉ Give examples of peripheral nociceptive pain. Answer: Osteoarthritis,
Rheumatoid arthritis, Cancer pain
◉ What is peripheral neuropathic pain due to?. Answer: Damage to, or
dysfunction of, peripheral nerves