Immunology NCLEX Exam Practice Questions with
Correct Verified A+ Answers
A 19-year-old male being tested for multiple allergies develops localized redness and swelling in reaction
to a patch skin test. Which intervention by the nurse would have the highest priority?
A. Notify the primary care provider
B. Apply a topical anti-inflammatory cream
C. Remove the patch and extract from the skin
D. Administer oral diphenhydramine (Benadryl) - Answer C. Remove the patch and extract from the skin
If a severe reaction to a patch skin test occurs, the nurse should immediately remove the patch and the
extract from the skin. Next the nurse should apply a topical anti-inflammatory cream to the site. A
subcutaneous injection of epinephrine may also be necessary but would need a health care provider's
order.
The nurse is teaching a 24-year-old female patient who has a latex allergy about preventing and treating
allergic reactions. Which statement, if made by the patient, indicates a need for further teaching?
A. "My dentist should be told about my latex allergy."
B. "I should avoid foods such as bananas, avocados, and kiwi."
C. "I will use vinyl gloves for activities such as housekeeping."
D. "Because my reactions are not severe, I will not need an EpiPen." - Answer D. "Because my reactions
are not severe, I will not need an EpiPen."
An individual with latex allergies should carry an injectable epinephrine pen. The proteins in latex are
similar to the proteins in certain foods and may cause an allergic reaction in people who are allergic to
latex. Foods to avoid include banana, avocado, chestnut, kiwi, tomato, water chestnuts, guava,
hazelnuts, potatoes, peaches, grapes, and apricots. Vinyl gloves are not latex and are safe to use.
Individuals with latex allergies need to share this information with all health care providers and wear a
medical alert bracelet.
A 34-year-old female patient who has systemic lupus erythematosus is receiving plasmapheresis to treat
an acute attack. What symptoms will the nurse monitor to determine if the patient develops
complications related to the procedure?
, A. Hypotension, paresthesias and dizziness
B. Polyuria, decreased reflexes, and lethargy
C. Intense thirst, flushed skin, and weight gain
D. Abdominal cramping, diarrhea, and leg weakness - Answer A. Hypotension, paresthesias, and
dizziness
Common complications associated with plasmapheresis are hypotension and citrate toxicity. Citrate is
used as an anticoagulant and may cause hypocalcemia, which may manifest as headache, paresthesias,
and dizziness. Polyuria, decreased reflexes, and lethargy are symptoms of hypercalcemia. Abdominal
cramping, diarrhea, and leg weakness indicate hyperkalemia. Intense thirst, flushed skin, and weight
gain indicate hypernatremia with normal or increased extracellular fluid volume.
A 58-year-old man who is waiting for a kidney transplant asks the nurse to explain the difference
between a negative and positive cross match. Which statement by the nurse would be the most
accurate response?
A. "A negative cross match means that both the donor and recipient are Rh negative, and the transplant
is safe."
B. "A negative cross match means that no preformed antibodies are present and the transplant would
be safe."
C. "A positive cross match means the blood type is the same between donor and recipient, and the
transplant is safe."
D. "A positive cross match means that both the donor and the recipient have antigens that are similar,
and the transplant would be safe." - Answer B. "A negative cross match means that no preformed
antibodies are present and the transplant would be safe."
A cross match uses serum from the recipient mixed with donor lymphocytes to test for any preformed
antibodies to the potential donor organ. A positive cross match indicates that the recipient has cytotoxic
antibodies to the donor and is an absolute contraindication to transplantation. A negative cross match
indicates that no preformed antibodies are present and it is safe to proceed with transplantation.
Which patient is at highest risk for developing graft-versus-host disease?
A. A 65-year-old man who received an autologous blood transfusion
B. A 40-year-old man who received a kidney transplant from a living donor
C. A 65-year-old woman who received a pancreas and kidney from a deceased donor
Correct Verified A+ Answers
A 19-year-old male being tested for multiple allergies develops localized redness and swelling in reaction
to a patch skin test. Which intervention by the nurse would have the highest priority?
A. Notify the primary care provider
B. Apply a topical anti-inflammatory cream
C. Remove the patch and extract from the skin
D. Administer oral diphenhydramine (Benadryl) - Answer C. Remove the patch and extract from the skin
If a severe reaction to a patch skin test occurs, the nurse should immediately remove the patch and the
extract from the skin. Next the nurse should apply a topical anti-inflammatory cream to the site. A
subcutaneous injection of epinephrine may also be necessary but would need a health care provider's
order.
The nurse is teaching a 24-year-old female patient who has a latex allergy about preventing and treating
allergic reactions. Which statement, if made by the patient, indicates a need for further teaching?
A. "My dentist should be told about my latex allergy."
B. "I should avoid foods such as bananas, avocados, and kiwi."
C. "I will use vinyl gloves for activities such as housekeeping."
D. "Because my reactions are not severe, I will not need an EpiPen." - Answer D. "Because my reactions
are not severe, I will not need an EpiPen."
An individual with latex allergies should carry an injectable epinephrine pen. The proteins in latex are
similar to the proteins in certain foods and may cause an allergic reaction in people who are allergic to
latex. Foods to avoid include banana, avocado, chestnut, kiwi, tomato, water chestnuts, guava,
hazelnuts, potatoes, peaches, grapes, and apricots. Vinyl gloves are not latex and are safe to use.
Individuals with latex allergies need to share this information with all health care providers and wear a
medical alert bracelet.
A 34-year-old female patient who has systemic lupus erythematosus is receiving plasmapheresis to treat
an acute attack. What symptoms will the nurse monitor to determine if the patient develops
complications related to the procedure?
, A. Hypotension, paresthesias and dizziness
B. Polyuria, decreased reflexes, and lethargy
C. Intense thirst, flushed skin, and weight gain
D. Abdominal cramping, diarrhea, and leg weakness - Answer A. Hypotension, paresthesias, and
dizziness
Common complications associated with plasmapheresis are hypotension and citrate toxicity. Citrate is
used as an anticoagulant and may cause hypocalcemia, which may manifest as headache, paresthesias,
and dizziness. Polyuria, decreased reflexes, and lethargy are symptoms of hypercalcemia. Abdominal
cramping, diarrhea, and leg weakness indicate hyperkalemia. Intense thirst, flushed skin, and weight
gain indicate hypernatremia with normal or increased extracellular fluid volume.
A 58-year-old man who is waiting for a kidney transplant asks the nurse to explain the difference
between a negative and positive cross match. Which statement by the nurse would be the most
accurate response?
A. "A negative cross match means that both the donor and recipient are Rh negative, and the transplant
is safe."
B. "A negative cross match means that no preformed antibodies are present and the transplant would
be safe."
C. "A positive cross match means the blood type is the same between donor and recipient, and the
transplant is safe."
D. "A positive cross match means that both the donor and the recipient have antigens that are similar,
and the transplant would be safe." - Answer B. "A negative cross match means that no preformed
antibodies are present and the transplant would be safe."
A cross match uses serum from the recipient mixed with donor lymphocytes to test for any preformed
antibodies to the potential donor organ. A positive cross match indicates that the recipient has cytotoxic
antibodies to the donor and is an absolute contraindication to transplantation. A negative cross match
indicates that no preformed antibodies are present and it is safe to proceed with transplantation.
Which patient is at highest risk for developing graft-versus-host disease?
A. A 65-year-old man who received an autologous blood transfusion
B. A 40-year-old man who received a kidney transplant from a living donor
C. A 65-year-old woman who received a pancreas and kidney from a deceased donor
