Page 1 of 157
BROKER EXAM LATEST 2026/27 UPDATE
WITH 125 MULTIPLE CHOICE QUESTIONS,
CORRECTLY ANSWERED AND ALREADY
GRADED A+ |VERIFIED LEARNERS|
1. A patient with chronic alcoholism develops hepatomegaly.
Which cellular adaptation is most likely?
A. Hyperplasia
B. Metaplasia
C. Hypertrophy
D. Dysplasia
Answer: C – Hypertrophy
Rationale: Hepatocytes increase in size due to increased
metabolic demand from alcohol metabolism.
,Page 2 of 157
2. A smoker’s bronchial epithelium changes from ciliated
columnar to stratified squamous. This is:
A. Hyperplasia
B. Metaplasia
C. Anaplasia
D. Dysplasia
Answer: B – Metaplasia
Rationale: Reversible replacement of one differentiated cell type
with another (adaptive, but may predispose to malignancy).
3. Which finding is most characteristic of irreversible cell
injury?
A. ATP depletion
B. Nuclear pyknosis
C. Cell swelling
D. Decreased protein synthesis
Answer: B – Nuclear pyknosis
Rationale: Pyknosis (nuclear shrinkage & condensation) indicates
irreversible damage, unlike early reversible swelling.
,Page 3 of 157
4. A patient has a myocardial infarction. Which type of
necrosis is seen in the heart?
A. Coagulative
B. Liquefactive
C. Caseous
D. Fat
Answer: A – Coagulative
Rationale: Coagulative necrosis occurs in solid organs (except
brain) due to ischemia; architecture preserved.
5. A stroke patient develops brain tissue softening and cyst
formation. This is:
A. Coagulative necrosis
B. Liquefactive necrosis
C. Gangrenous necrosis
D. Fibrinoid necrosis
Answer: B – Liquefactive necrosis
Rationale: Brain has high lipids/enzymes; necrosis leads to
liquefaction.
, Page 4 of 157
6. A patient with tuberculosis has a lung lesion with “cheese-
like” appearance. This is:
A. Coagulative necrosis
B. Liquefactive necrosis
C. Caseous necrosis
D. Fat necrosis
Answer: C – Caseous necrosis
Rationale: Combination of coagulative and liquefactive necrosis;
granulomatous inflammation.
7. Acute pancreatitis causes necrosis of peripancreatic fat. This
is:
A. Coagulative necrosis
B. Fat necrosis
C. Fibrinoid necrosis
D. Gangrenous necrosis
Answer: B – Fat necrosis
Rationale: Lipases break triglycerides into fatty acids, which bind
calcium (saponification).
BROKER EXAM LATEST 2026/27 UPDATE
WITH 125 MULTIPLE CHOICE QUESTIONS,
CORRECTLY ANSWERED AND ALREADY
GRADED A+ |VERIFIED LEARNERS|
1. A patient with chronic alcoholism develops hepatomegaly.
Which cellular adaptation is most likely?
A. Hyperplasia
B. Metaplasia
C. Hypertrophy
D. Dysplasia
Answer: C – Hypertrophy
Rationale: Hepatocytes increase in size due to increased
metabolic demand from alcohol metabolism.
,Page 2 of 157
2. A smoker’s bronchial epithelium changes from ciliated
columnar to stratified squamous. This is:
A. Hyperplasia
B. Metaplasia
C. Anaplasia
D. Dysplasia
Answer: B – Metaplasia
Rationale: Reversible replacement of one differentiated cell type
with another (adaptive, but may predispose to malignancy).
3. Which finding is most characteristic of irreversible cell
injury?
A. ATP depletion
B. Nuclear pyknosis
C. Cell swelling
D. Decreased protein synthesis
Answer: B – Nuclear pyknosis
Rationale: Pyknosis (nuclear shrinkage & condensation) indicates
irreversible damage, unlike early reversible swelling.
,Page 3 of 157
4. A patient has a myocardial infarction. Which type of
necrosis is seen in the heart?
A. Coagulative
B. Liquefactive
C. Caseous
D. Fat
Answer: A – Coagulative
Rationale: Coagulative necrosis occurs in solid organs (except
brain) due to ischemia; architecture preserved.
5. A stroke patient develops brain tissue softening and cyst
formation. This is:
A. Coagulative necrosis
B. Liquefactive necrosis
C. Gangrenous necrosis
D. Fibrinoid necrosis
Answer: B – Liquefactive necrosis
Rationale: Brain has high lipids/enzymes; necrosis leads to
liquefaction.
, Page 4 of 157
6. A patient with tuberculosis has a lung lesion with “cheese-
like” appearance. This is:
A. Coagulative necrosis
B. Liquefactive necrosis
C. Caseous necrosis
D. Fat necrosis
Answer: C – Caseous necrosis
Rationale: Combination of coagulative and liquefactive necrosis;
granulomatous inflammation.
7. Acute pancreatitis causes necrosis of peripancreatic fat. This
is:
A. Coagulative necrosis
B. Fat necrosis
C. Fibrinoid necrosis
D. Gangrenous necrosis
Answer: B – Fat necrosis
Rationale: Lipases break triglycerides into fatty acids, which bind
calcium (saponification).
