2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
2025 OCR AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Verified Question paper with Marking Scheme Attached
Oxford Cambridge and RSA
Monday 12 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use the lined
pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be given
for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (CE/SG) 329633/4 Turn over
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
,2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1]
© OCR 2025
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
,2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
3
3 The transmission electron micrograph shows the ultrastructure of a mammalian cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
[1]
© OCR 2025 Turn over
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
, 2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
4
4 A student observed a blood sample using a light microscope with a calibrated eyepiece graticule. They
measured the diameter of a lymphocyte and calculated its actual diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the addition of a fixed
quantity of substance Z.
Without substance Z
Rate of reaction
With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1]
© OCR 2025
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
2025 OCR AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Verified Question paper with Marking Scheme Attached
Oxford Cambridge and RSA
Monday 12 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use the lined
pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be given
for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (CE/SG) 329633/4 Turn over
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
,2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1]
© OCR 2025
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
,2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
3
3 The transmission electron micrograph shows the ultrastructure of a mammalian cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
[1]
© OCR 2025 Turn over
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
, 2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached.pdf
Attached.pdf
Attached.pdf
4
4 A student observed a blood sample using a light microscope with a calibrated eyepiece graticule. They
measured the diameter of a lymphocyte and calculated its actual diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the addition of a fixed
quantity of substance Z.
Without substance Z
Rate of reaction
With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1]
© OCR 2025
2025
2025
OCR
2025
OCR
ASOCR
Level
AS Level
ASBiology
Level
Biology
Biology
B (Advancing
B (Advancing
B (Advancing
Biology)
Biology)
Biology)
H02201
H02201
H02201
Foundations
Foundations
Foundations
of biology
of biology
of biology
Verified
Verified
Verified
Question
Question
Question
paper
paper
with
paper
with
Marking
with
Marking
Marking
Scheme
Scheme
Scheme
Attached
Attached.pdf
Attached.pdf
