NAPLEX Practice Test
225 Practice Questions
+ BONUS Oncology & HIV Questions
NAPLEX® is a federally registered trademark of the National Association of Boards of Pharmacy.
MedEd101 Inc, Cosmas Health, Inc. and its services are neither affiliated with nor endorsed by the NABP.
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1. A 34-year-old female presents with symptoms of fatigue, weight gain, increased sensitivity to cold,
worsened mood and constipation. Current lab work reveals a hemoglobin of 14.2 g/dL, creatinine
of 1.1 mg/dL, B12 of 400 pg/mL, folic acid of 15 ng/mL, and TSH of 26.5 mIU/L. Current
medications include: Synthroid 50 mcg daily, Zoloft (sertraline) 75 mg daily, and folic acid 1 mg
daily. The patient is taking all medications as directed. What would you recommend?
A. Increase Zoloft to 100 mg daily
B. Consider the addition of vitamin B12
C. Increase Synthroid to 75 mcg daily
D. None of the above
Based on the presented symptoms and lab results, the patient is likely experiencing
symptoms of hypothyroidism, which is evidenced by the elevated TSH level. Therefore, it
would be appropriate to increase the Synthroid (levothyroxine) dosage to improve symptoms.
There is no evidence to suggest that increasing the dosage of Zoloft (sertraline) would help
with the patient's symptoms, so Option A is not recommended.
The patient's B12 level is within the normal range, so there is no indication to add vitamin
B12 at this time, making Option B not recommended.
Therefore, the correct answer is C. Increase Synthroid to 75 mcg daily. However, it is
important for the patient to follow up with her healthcare provider for further evaluation and
monitoring.
2. How many mg of a medication will it take to create a 1,500 mL product at a concentration of
1:10,000?
Fill in the Blank: 150 mg
For weight/volume (w/v) ratios, 1:100 (1%) means 1 gram per 100 mL.
Therefore, 1:10,000 (0.01%) means 1 gram per 10,000 mL.
1 g/10,000 mL = 1,000 mg/10,000 mL = 0.1 mg/mL
Since 1,500 mL of total volume are needed at this concentration, multiply by 1,500 mL to
determine how many total milligrams are required.
0.1 mg/mL x 1500 mL = 150 mg
3. Which of the following would be most appropriate in a patient with HIV requiring PCP
(Pneumocystis carinii pneumonia) prophylaxis?
A. Doxycycline
B. Bactrim
C. Erythromycin
D. Augmentin
Bactrim (sulfamethoxazole-trimethoprim) is the drug of choice for PCP prophylaxis.
4. Which of the following medications for diabetes would carry the least risk of hypoglycemia?
A. Glucophage
B. Glucotrol
C. Lantus
D. Humalog
© Med Ed 101, Inc. View this practice test and download STUDY CHARTS at https://app.pyrls.com/naplex
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225 Practice Questions
+ BONUS Oncology & HIV Questions
NAPLEX® is a federally registered trademark of the National Association of Boards of Pharmacy.
MedEd101 Inc, Cosmas Health, Inc. and its services are neither affiliated with nor endorsed by the NABP.
AL Grawany
,This FREE NAPLEX Practice Exam was brought to you in collaboration with
Need more NAPLEX prep?
Get a Med Ed 101 NAPLEX PREP ALL ACCESS PASS
• 1800+ NAPLEX Practice Questions and Practice Exam
• 30+ Hour Recorded Review Course
Take 30% off
• 1,200+ Slide Deck 6 and 12 month passes
• Bonus Statistics Study Guide with promo code PYRLS
• Bonus Regulatory Study Guide
https://
Get Now
www.meded101.com
• Select Medication Comparison Tables
/naplex/
MORE CLINICAL PHARMACY EDUCATION FROM
https://MEDED101.COM
MEDED101.COM
https:// https://
www.amazon.com/ Flippin’ Pharmacology NAPLEX Nuggets
Flash Cards www.amazon.
Flippin- NAPLEX study book
Pharmacology- Nearly 600 medications on com/NAPLEX- https://www.amazon.com/
NAPLEX-Nuggets-Meded101-
Flash-Christianson- 292 spiral bound book Nuggets- Get on Amazon
Christianson-PharmD/dp/
B0BS9SX2JG/
PharmD/dp/ https://www.amazon.com/Flippin- Meded101-
B0BWSGKP46/ Get on Amazon
Pharmacology-Flash-Christianson-
Christianson-
PharmD/dp/B0BWSGKP46/
PharmD/dp/
B0BS9SX2JG/
REAL LIFE PHARMACOLOGY PODCAST
A Meded101.com Production
https://
1,000,000+ Downloads Listen Now FREE
www.reallifephar
On on major podcast platforms!
macology.com/
• Free podcast and top drugs study guide
podcast-2/
• 300+ episodes on specific drugs and/or drug classes
AL Grawany
,Experience all the benefits of Pyrls with a Pro Membership!
Subscribe today within our mobile app or website!
Pyrls Pro Membership Quickly access counseling points and pearls!
Featuring
!
500+ Top Drug Summaries
"
Charts, Tables, Reviews, Calculators
⚠
Drug Interaction Checking Tool
$
Full Mobile App and Web Access
Learn & reference with pharmacotherapy reviews!
® 2023 Cosmas Health, Inc. and/or its affiliates. All rights reserved.
AL Grawany
, View questions only PDF here
1. A 34-year-old female presents with symptoms of fatigue, weight gain, increased sensitivity to cold,
worsened mood and constipation. Current lab work reveals a hemoglobin of 14.2 g/dL, creatinine
of 1.1 mg/dL, B12 of 400 pg/mL, folic acid of 15 ng/mL, and TSH of 26.5 mIU/L. Current
medications include: Synthroid 50 mcg daily, Zoloft (sertraline) 75 mg daily, and folic acid 1 mg
daily. The patient is taking all medications as directed. What would you recommend?
A. Increase Zoloft to 100 mg daily
B. Consider the addition of vitamin B12
C. Increase Synthroid to 75 mcg daily
D. None of the above
Based on the presented symptoms and lab results, the patient is likely experiencing
symptoms of hypothyroidism, which is evidenced by the elevated TSH level. Therefore, it
would be appropriate to increase the Synthroid (levothyroxine) dosage to improve symptoms.
There is no evidence to suggest that increasing the dosage of Zoloft (sertraline) would help
with the patient's symptoms, so Option A is not recommended.
The patient's B12 level is within the normal range, so there is no indication to add vitamin
B12 at this time, making Option B not recommended.
Therefore, the correct answer is C. Increase Synthroid to 75 mcg daily. However, it is
important for the patient to follow up with her healthcare provider for further evaluation and
monitoring.
2. How many mg of a medication will it take to create a 1,500 mL product at a concentration of
1:10,000?
Fill in the Blank: 150 mg
For weight/volume (w/v) ratios, 1:100 (1%) means 1 gram per 100 mL.
Therefore, 1:10,000 (0.01%) means 1 gram per 10,000 mL.
1 g/10,000 mL = 1,000 mg/10,000 mL = 0.1 mg/mL
Since 1,500 mL of total volume are needed at this concentration, multiply by 1,500 mL to
determine how many total milligrams are required.
0.1 mg/mL x 1500 mL = 150 mg
3. Which of the following would be most appropriate in a patient with HIV requiring PCP
(Pneumocystis carinii pneumonia) prophylaxis?
A. Doxycycline
B. Bactrim
C. Erythromycin
D. Augmentin
Bactrim (sulfamethoxazole-trimethoprim) is the drug of choice for PCP prophylaxis.
4. Which of the following medications for diabetes would carry the least risk of hypoglycemia?
A. Glucophage
B. Glucotrol
C. Lantus
D. Humalog
© Med Ed 101, Inc. View this practice test and download STUDY CHARTS at https://app.pyrls.com/naplex
AL Grawany