CPIA BUNDLED EXAMS PRACTICE SCRIPT
2026 QUESTIONS WITH SOLUTIONS
GRADED A+
⩥ The Health Research Extension Act of 1985 directs ______ to
establish guidelines for the proper care and treatment of animals used in
research. Answer: the Secretary of Health and Human Services
⩥ In 1986, the PHS Policy incorporated the ________ by the
Interagency Research Animal Committee and adopted by US
Government agencies that use vertebrate animals. Answer: U.S.
Government Principles for the Utilization and Care of Vertebrate
Animals Used in Testing, Research, and Training
⩥ IACUC membership requirements for PHS Assurance. Answer: 5
members:
One veterinarian (training/experience in lab animal medicine)
One scientist (experience in research)
One nonscientific member
One not affiliated member
⩥ PHS Policy mandates that animal care and use programs must operate
in accordance with four specific laws and guidelines. Answer: 1. The
Animal Welfare Act
,2. United States Government Principles for the Utilization and Care of
Vertebrate Animals Used in Testing, Research, and Training
3. The Guide for the Care and Use of Laboratory Animals
4. AVMA Guidelines for the Euthanasia of Animals
⩥ Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts
1, 2, and 3. Answer: Animal Welfare Regulations that are implemented
by the USDA/APHIS/AC
⩥ Clarified humane care, minimization of pain and distress,
consideration of alternatives, institutional animal care and use
committees, psychological well-being of primates, and exercise for dogs.
Answer: 1985 amendments to the AWA
⩥ Which term is defined in the Guide as "all measures to control known
or unknown infections in laboratory animals."
a. Biosecurity
b. Stabilization
c. Quarantine
d. Biosafety. Answer: a. Biosecurity
⩥ Which of the following statements about multiple survival surgical
procedures on a single animal is TRUE?
, a. The Guide's definition of "major" surgery is rigid, and does not
provide for any interpretation by the veterinarian or the IACUC.
b. When USDA-covered species are used, the Animal Welfare
Regulations' definition of "major" surgery takes precedence.
c. The Animal Welfare Regulations allow for the interpretation of
"major" surgery to be evaluated on a case-by-case basis by the IACUC.
d. The Guide's requirement that multiple major survival surgeries must
be scientifically justified and included in the IACUC-approved protocol
only applies to non-rodent mammals.. Answer: b. When USDA-covered
species are used, the Animal Welfare Regulations' definition of "major"
surgery takes precedence.
⩥ Animals using which type of thermoregulation depend mostly on
environmental temperature to maintain their internal physiology?.
Answer: Poikilothermic
⩥ Which should be provided in the environment of a semi-aquatic
animal?
a. porous substrate
b. recirculating system
c. a terrestrial area
d. low humidity level. Answer: c. a terrestrial area
⩥ Which statement is TRUE for the use of agricultural animals in
biomedical research, when they are maintained in a farm setting?
2026 QUESTIONS WITH SOLUTIONS
GRADED A+
⩥ The Health Research Extension Act of 1985 directs ______ to
establish guidelines for the proper care and treatment of animals used in
research. Answer: the Secretary of Health and Human Services
⩥ In 1986, the PHS Policy incorporated the ________ by the
Interagency Research Animal Committee and adopted by US
Government agencies that use vertebrate animals. Answer: U.S.
Government Principles for the Utilization and Care of Vertebrate
Animals Used in Testing, Research, and Training
⩥ IACUC membership requirements for PHS Assurance. Answer: 5
members:
One veterinarian (training/experience in lab animal medicine)
One scientist (experience in research)
One nonscientific member
One not affiliated member
⩥ PHS Policy mandates that animal care and use programs must operate
in accordance with four specific laws and guidelines. Answer: 1. The
Animal Welfare Act
,2. United States Government Principles for the Utilization and Care of
Vertebrate Animals Used in Testing, Research, and Training
3. The Guide for the Care and Use of Laboratory Animals
4. AVMA Guidelines for the Euthanasia of Animals
⩥ Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts
1, 2, and 3. Answer: Animal Welfare Regulations that are implemented
by the USDA/APHIS/AC
⩥ Clarified humane care, minimization of pain and distress,
consideration of alternatives, institutional animal care and use
committees, psychological well-being of primates, and exercise for dogs.
Answer: 1985 amendments to the AWA
⩥ Which term is defined in the Guide as "all measures to control known
or unknown infections in laboratory animals."
a. Biosecurity
b. Stabilization
c. Quarantine
d. Biosafety. Answer: a. Biosecurity
⩥ Which of the following statements about multiple survival surgical
procedures on a single animal is TRUE?
, a. The Guide's definition of "major" surgery is rigid, and does not
provide for any interpretation by the veterinarian or the IACUC.
b. When USDA-covered species are used, the Animal Welfare
Regulations' definition of "major" surgery takes precedence.
c. The Animal Welfare Regulations allow for the interpretation of
"major" surgery to be evaluated on a case-by-case basis by the IACUC.
d. The Guide's requirement that multiple major survival surgeries must
be scientifically justified and included in the IACUC-approved protocol
only applies to non-rodent mammals.. Answer: b. When USDA-covered
species are used, the Animal Welfare Regulations' definition of "major"
surgery takes precedence.
⩥ Animals using which type of thermoregulation depend mostly on
environmental temperature to maintain their internal physiology?.
Answer: Poikilothermic
⩥ Which should be provided in the environment of a semi-aquatic
animal?
a. porous substrate
b. recirculating system
c. a terrestrial area
d. low humidity level. Answer: c. a terrestrial area
⩥ Which statement is TRUE for the use of agricultural animals in
biomedical research, when they are maintained in a farm setting?
