CPIA Exam Questions and Answers | Detailed
Review with Correct Solutions | Grade A+
• Which of the following should be considered a significant change to an animal
use proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration -✓✓C. change in anesthetic agent
• Which of the following entities are required to release information per the
Freedom of Information Act?
A. OLAW
B. AAALAC
C. IACUC
D. HSUS -✓✓A. OLAW
• Training and instruction of personnel must include guidance in which of the
following areas?
A. Effective writing of animal use proposals
B. Proper use of personal protective equipment
C. Appropriate communication with animal activist groups
D. Research or testing methods that limit the use of animals -✓✓D. Research or
testing methods that limit the use of animals
• Which of the following procedures may correctly be applied to Designated
Member Review?
A. The IACUC Chair appoints one member to do the Designated Member Review.
B. The designated member reviewer is authorized to approve, require
modifications, or disapprove the proposal.
C. All members receive information about the proposal and send their votes to the
designated member reviewer for tallying.
D. Designated member review may be utilized to review proposals when there is
insufficient time to notify the full membership of the proposal details. -✓✓A. The
IACUC Chair appoints one member to do the Designated Member Review.
• In which of the following circumstances may animal work begin before receipt of
IACUC approval?
,A. It is a continuing study awaiting three year renewal and for which the renewal
protocol has been submitted to the IACUC.
B. It is a small pilot study on non-AWAR species.
C. It is a teaching activity that uses students' personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC
approval. -✓✓D. There are no circumstances in which animal work may begin
before IACUC approval.
• Which of the statements below about the responsibility and authority of the
Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the
animal care and use program.
B. The IO must be the institution's Chief Executive Officer or some appointed by
him with authority to fund resources.
C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
D. The IO may suspend an animal activity that was previously approved by the
IACUC. -✓✓C. The IO may reinstate an animal activity that was previously
suspended by the IACUC.
• With regard to conducting official IACUC business, the definition of a quorum
is:
A. More than fifty percent (a majority) of voting members.
B. Fifty percent of voting and non-voting members combined.
C. More than fifty percent (a majority) of voting and non-voting members
combined.
D. Fifty percent of the voting members. -✓✓A. More than fifty percent (a
majority) of voting members
• The proper sequence for a designated member review by the IACUC is:
A. Review materials are sent to all voting members, full committee review is not
requested by any member, the chairperson assigns one or more IACUC members
as designated reviewers.
B. Review materials are sent to a quorum of designated reviewers, review results
are solicited from designated reviewers, full committee approval of results is
requested.
C. Review materials are sent to all voting members, a majority of members do not
request full committee review, the chairperson assigns one or more IACUC
members as designated reviewers.
,D. Review materials are sent to a quorum of voting members, a majority of a
quorum does not request full committee review, the chairperson assigns one or
more IACUC members as designated reviewers. -✓✓A. Review materials are sent
to all voting members, full committee review is not requested by any member, the
chairperson assigns one or more IACUC members as designated reviewers.
• Notifying investigators of IACUC protocol review outcomes in writing is:
A. A common courtesy not required by regulatory authorities.
B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only
after the minutes have been prepared and approved by the IACUC during a
convened meeting.
C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.
D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only
after the IO is notified of the review outcome. -✓✓C. Required by both the USDA
Animal Welfare Act Regulations and PHS Policy.
• According to the Animal Welfare Act Regulations of the USDA, when
conducting a semi-annual evaluation, the IACUC must conduct the evaluation:
A. With at least 1 IACUC member and allow participation by any member who
wishes to do so.
B. With at least 2 IACUC members and allow participation by any member who
wishes to do so.
C. With a majority of IACUC members present, including the non-affiliated
member.
D. With all IACUC members present. -✓✓B. With at least 2 IACUC members and
allow participation by any member who wishes to do so.
• Who is given the authority to decide if a deficiency identified during a semi-
annual IACUC evaluation is significant or minor?
A. The IACUC and IO together.
B. The veterinarian and the IACUC together.
C. Only the IACUC.
D. Only the IO. -✓✓A. The IACUC and IO together.
• What information must be provided in the report for deficiencies identified
during the IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant
deficiencies, and a description of minor deficiencies.
, B. A reasonable and specific plan for correcting significant and minor deficiencies
and a schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and
the institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the
corrections and the IACUC members in charge of verifying the corrections. -✓✓B.
A reasonable and specific plan for correcting significant and minor deficiencies
and a schedule for completing the corrective actions.
• Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding. -✓✓D. Institutions that accept PHS
funding.
• The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review. -✓✓C. Replacement, reduction, and refinement.
• What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment. -✓✓B. Provides assistance with alternatives and database searches.
• Which agency requires an annual report of the number of animals used by
pain/distress category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
D. United States Department of Agriculture -✓✓D. United States Department of
Agriculture
Review with Correct Solutions | Grade A+
• Which of the following should be considered a significant change to an animal
use proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration -✓✓C. change in anesthetic agent
• Which of the following entities are required to release information per the
Freedom of Information Act?
A. OLAW
B. AAALAC
C. IACUC
D. HSUS -✓✓A. OLAW
• Training and instruction of personnel must include guidance in which of the
following areas?
A. Effective writing of animal use proposals
B. Proper use of personal protective equipment
C. Appropriate communication with animal activist groups
D. Research or testing methods that limit the use of animals -✓✓D. Research or
testing methods that limit the use of animals
• Which of the following procedures may correctly be applied to Designated
Member Review?
A. The IACUC Chair appoints one member to do the Designated Member Review.
B. The designated member reviewer is authorized to approve, require
modifications, or disapprove the proposal.
C. All members receive information about the proposal and send their votes to the
designated member reviewer for tallying.
D. Designated member review may be utilized to review proposals when there is
insufficient time to notify the full membership of the proposal details. -✓✓A. The
IACUC Chair appoints one member to do the Designated Member Review.
• In which of the following circumstances may animal work begin before receipt of
IACUC approval?
,A. It is a continuing study awaiting three year renewal and for which the renewal
protocol has been submitted to the IACUC.
B. It is a small pilot study on non-AWAR species.
C. It is a teaching activity that uses students' personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC
approval. -✓✓D. There are no circumstances in which animal work may begin
before IACUC approval.
• Which of the statements below about the responsibility and authority of the
Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the
animal care and use program.
B. The IO must be the institution's Chief Executive Officer or some appointed by
him with authority to fund resources.
C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
D. The IO may suspend an animal activity that was previously approved by the
IACUC. -✓✓C. The IO may reinstate an animal activity that was previously
suspended by the IACUC.
• With regard to conducting official IACUC business, the definition of a quorum
is:
A. More than fifty percent (a majority) of voting members.
B. Fifty percent of voting and non-voting members combined.
C. More than fifty percent (a majority) of voting and non-voting members
combined.
D. Fifty percent of the voting members. -✓✓A. More than fifty percent (a
majority) of voting members
• The proper sequence for a designated member review by the IACUC is:
A. Review materials are sent to all voting members, full committee review is not
requested by any member, the chairperson assigns one or more IACUC members
as designated reviewers.
B. Review materials are sent to a quorum of designated reviewers, review results
are solicited from designated reviewers, full committee approval of results is
requested.
C. Review materials are sent to all voting members, a majority of members do not
request full committee review, the chairperson assigns one or more IACUC
members as designated reviewers.
,D. Review materials are sent to a quorum of voting members, a majority of a
quorum does not request full committee review, the chairperson assigns one or
more IACUC members as designated reviewers. -✓✓A. Review materials are sent
to all voting members, full committee review is not requested by any member, the
chairperson assigns one or more IACUC members as designated reviewers.
• Notifying investigators of IACUC protocol review outcomes in writing is:
A. A common courtesy not required by regulatory authorities.
B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only
after the minutes have been prepared and approved by the IACUC during a
convened meeting.
C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.
D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only
after the IO is notified of the review outcome. -✓✓C. Required by both the USDA
Animal Welfare Act Regulations and PHS Policy.
• According to the Animal Welfare Act Regulations of the USDA, when
conducting a semi-annual evaluation, the IACUC must conduct the evaluation:
A. With at least 1 IACUC member and allow participation by any member who
wishes to do so.
B. With at least 2 IACUC members and allow participation by any member who
wishes to do so.
C. With a majority of IACUC members present, including the non-affiliated
member.
D. With all IACUC members present. -✓✓B. With at least 2 IACUC members and
allow participation by any member who wishes to do so.
• Who is given the authority to decide if a deficiency identified during a semi-
annual IACUC evaluation is significant or minor?
A. The IACUC and IO together.
B. The veterinarian and the IACUC together.
C. Only the IACUC.
D. Only the IO. -✓✓A. The IACUC and IO together.
• What information must be provided in the report for deficiencies identified
during the IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant
deficiencies, and a description of minor deficiencies.
, B. A reasonable and specific plan for correcting significant and minor deficiencies
and a schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and
the institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the
corrections and the IACUC members in charge of verifying the corrections. -✓✓B.
A reasonable and specific plan for correcting significant and minor deficiencies
and a schedule for completing the corrective actions.
• Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding. -✓✓D. Institutions that accept PHS
funding.
• The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review. -✓✓C. Replacement, reduction, and refinement.
• What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment. -✓✓B. Provides assistance with alternatives and database searches.
• Which agency requires an annual report of the number of animals used by
pain/distress category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
D. United States Department of Agriculture -✓✓D. United States Department of
Agriculture
