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Microbiology 2420: Chapters 15 and 16, Immunity, Test Questions and All Correct Answers.

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Innate immunity - Answer Resistance to pathogens conferred by barriers, chemicals, cells and processes that remain unchanged upon subsequent infections with the same pathogen Examples of innate immunity - Answer Skin Stomach acid (pH) epithelial barriers phagocytes Natural Killer cells (NK cells) Fixed phagocytes of the epidermis - Answer Dendritic cells Where are mucus-secreting membranes found? - Answer Urinary system Digestive cavity Respiratory passages The complement system involves - Answer Serum proteins involved in nonspecific defense It involves factors B, D and P - Answer Alternative pathway What would happen if complement was not inactivated? - Answer It would make holes in the body's own cells Gamma interferon - Answer The type of interferon present late in an infection Interferons - Answer Protein molecules released by host cell to nonspecifically inhibit the spread of viruses Cause many of the symptoms typically associated with viral infections What binds iron? - Answer Lactoferrin

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Microbiology 2420: Chapters 15 and
16, Immunity, Test Questions and All
Correct Answers.


Innate immunity - Answer Resistance to pathogens conferred by barriers, chemicals, cells
and processes that remain unchanged upon subsequent infections with the same pathogen



Examples of innate immunity - Answer Skin

Stomach acid (pH)

epithelial barriers

phagocytes

Natural Killer cells (NK cells)



Fixed phagocytes of the epidermis - Answer Dendritic cells



Where are mucus-secreting membranes found? - Answer Urinary system

Digestive cavity

Respiratory passages



The complement system involves - Answer Serum proteins involved in nonspecific defense



It involves factors B, D and P - Answer Alternative pathway



What would happen if complement was not inactivated? - Answer It would make holes in
the body's own cells



Gamma interferon - Answer The type of interferon present late in an infection



Interferons - Answer Protein molecules released by host cell to nonspecifically inhibit the
spread of viruses



Cause many of the symptoms typically associated with viral infections



What binds iron? - Answer Lactoferrin

,Siderophores

Transferrin



Goblet cell function - Answer Secrete mucus



Lysozyme function - Answer Breaks bonds in bacterial cell well



Kupffer cell - Answer Phagocytic cell in the liver



Dendritic cell function - Answer Devours pathogens in the epidermis of skin



Cell from sebaceous gland - Answer Secretes sebum



Bone marrow stem cell - Answer Develops into formed elements of the blood



Eosinopil - Answer Leukocyte that primarily attacks parasitic worms



Alveolar macrophage - Answer Phagocytic cell in the lungs



Microglia - Answer Phagocytic cell in the CNS



Wandering macrophage - Answer Intercellular scavenger



Adaptive immunity - Answer Resistance against pathogens that acts more efficiently upon
subsequent infections with the same pathogens



The body's ability to recognize and then mount a defense against distinct invaders and their
products



5 distinctive attributes of adaptive immunity - Answer Specificity

Inducibility

Clonality

Unresponsiveness to self

Memory

, 2 types of Lymphocytes - Answer B lymphocytes/cells (mature in red bone marrow)

T lymphocytes/cells (mature in thymus)



Humoral immune response - Answer Body mounts responses against exogenous pathogens.
Activates only in response to specific pathogens



Cell-mediated immune response - Answer Responds to intracellular pathogens and
abnormal body cells



The most common intracellular pathogens are viruses but response also effective against cancer
cells and intracellular protozoa/bacteria



Antigen - Answer Protein on a surface pathogen that initiates an immune response



Epitope - Answer The 3-dimensional shape of a region of an antigen that is recognized by the
immune system



Ex: Bacterial cell walls, capsules, pili, flagella, proteins of viruses, fungi and protozoa



Paratope - Answer Antibody combining site



Haptens - Answer Molecules so small they evade detection but can become antigenic when
bound to larger carrier molecules (often proteins)



Examples of Haptens - Answer Antibiotics

Analgesics

Poison Ivy



3 types of antigens - Answer Exogenous antigens

Endogenous antigens

Autoantigens



Exogenous antigens - Answer Antigens produced by microorganisms that multiply outside
the cells of the body.



Include toxins and other secretions and components of microbial cell walls, membranes, flagella
and pili

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