ADVANCED PHARMACOLOGY FINAL EXAM
2026-2027 QUESTIONS WITH VERIFIED
ANSWERS GRADED A+
What is the purpose of administering a vasodilating drug to a patient in heart
failure?
Decrease afterload.
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy?
To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate?
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with?
Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
Aldosterone antagonist
,Heparin exerts its therapeutic action by what?
Upregulating the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending drug is administered during
an anaphylactic reaction.
Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension?
Thiazide diuretics
What is the effect of cardiac glycosides?
Digitalis glycosides have a negative chronotropic effect on the cardiac muscle
cells.
Amenorrhea is the most common side effect of which birth control medication?
Medroxyprogesterone (Depo-Provera)
, What are some contrindications for HMG-co A reductase inhibitors (statins)?
They cause myopathies, especially at higher doses or in combination with certain
drugs. They should never be used in patients taking Warfarin (Coumadin).
Which drug can reduce serum LDL the most in patients with hyperlipidemia?
Lovastatin (Mevacor)
Which drug is contrindicated in a patient with Myasthena Gravis?
Procainamide (Pronestyl).
What action is most effective in decreasing the risk of hyperkalemia associated
with the start of angiotensin-converting enzyme inhibitor (ACEI) therapy?
Making sure that the patient is well hydrated.
What factor influences plasma protein drug binding and distribution of that drug?
The amount of albumin available in the blood stream.
What does the half-life of a medication determine?
2026-2027 QUESTIONS WITH VERIFIED
ANSWERS GRADED A+
What is the purpose of administering a vasodilating drug to a patient in heart
failure?
Decrease afterload.
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy?
To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate?
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with?
Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
Aldosterone antagonist
,Heparin exerts its therapeutic action by what?
Upregulating the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending drug is administered during
an anaphylactic reaction.
Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension?
Thiazide diuretics
What is the effect of cardiac glycosides?
Digitalis glycosides have a negative chronotropic effect on the cardiac muscle
cells.
Amenorrhea is the most common side effect of which birth control medication?
Medroxyprogesterone (Depo-Provera)
, What are some contrindications for HMG-co A reductase inhibitors (statins)?
They cause myopathies, especially at higher doses or in combination with certain
drugs. They should never be used in patients taking Warfarin (Coumadin).
Which drug can reduce serum LDL the most in patients with hyperlipidemia?
Lovastatin (Mevacor)
Which drug is contrindicated in a patient with Myasthena Gravis?
Procainamide (Pronestyl).
What action is most effective in decreasing the risk of hyperkalemia associated
with the start of angiotensin-converting enzyme inhibitor (ACEI) therapy?
Making sure that the patient is well hydrated.
What factor influences plasma protein drug binding and distribution of that drug?
The amount of albumin available in the blood stream.
What does the half-life of a medication determine?
