NR 568/ NR568 Midterm Exam – Advanced Pharmacology for AGPCNP 2026/2027 | Chamberlain | Latest Questions & Verified Answers

NR 568/ NR568 Midterm Exam – Advanced Pharmacology for AGPCNP 2026/2027 | Chamberlain | Latest Questions & Verified Answers Q: Treatment for Tinea Cruris (ringworm of the groin) Answer Topical works well and should be continue 1 week after the symptoms have cleared. If Severe, give systemic antigungal like Clotrimazole or both topical and systemic glucocorticoids may be needed as well. T.B.C if severe Q: Treatment for Tinea Pedis (ringworm of the foot or athletes foot) Answer T.B Terbinafine BUtenafine Q: Treatment for Tinea Corporis (ringworm of the body) Answer Topical Azole or Allylamine and should be continued 1 week after the symptoms has cleared.For severe cases - systemic anti-fungal agent like griseofulvin is givenT.B Q: Tinea Capitis (ringworm of the scalp) Answer Oral griseofulvin should be take 6 to 8 weeks as a standard therapy. or Oral Terbinafine which can be take for 2 to 4 weeks (more effective) G.T Q: Treatment for oral candidiasis (thrush) Answer Topical agents - nystatin, clotrimaozle and miconazole If immunocompromised host, oral therapy of flucanozale or ketoconazole Q: Treatment for asperigillosis (farmers lung) Answer drug of choice is voriconazole alt drugs: A.B.I.I.PC.M Amphotericin B Isavuconazonium Itraconazole Posaconazole Caspofungin Micafungin Q: What do you avoid to combine with Voriconazole? Answer Phenobarbital. Because it is a CYP450 inducer that if given with Voriconazole will impact the levels and will not be able to reach the therapeutic level. Q: Patient teaching of Itraconazole Answer Avoid combing with drugs that metabolize by CYP3A4 Take PPIs at least 1 hour before or itraconazole 2 hours after And instruct to watch for signs of liver dysfunction. Q: Q: Example of a nucleotide reverse transcriptase inhibitor - NRTI drug Answer Abacavir Q: Diagnostic and Monitoring for Anthelmintics Answer Albendazole - liver function, cbc with diff and RFT Prazuquantel - LFT Ivermectic and Moxidectic - Opthalmologic exam if baseline is abnormal Q: CYP4A Answer W.C.D.Q "We Can D.Q" Warfarin Cyclosporin Digozin Quinidine Q: Adverse effect of Itraconazole Answer Can cause cardiac supperession, liver injury and GI issues. Can also cause rash, headache, edema, abdominal pain. Q: High risk patients with Albendazole Answer Impaired liver and renal function, anemia, bleeding disorder and infection. Q: High risk patients with Mebendazole Answer Liver disease, anemia, bleeding disorder and infection Q: High risk patients with Pyrantel Pamoate Answer Liver impairment, neonates should not be prescribed formualation containing benzyl alcohol or its derivatives Q: High risk patients with Ivermectic and Moxidectic Answer Hytpotension or taking anithypertensive drugs Q: High risk patients with Didanosine Answer Risk for pancreatitis is increase by a history of alcoholism or pancreatitis and by use of IV pentamidine Q: High risk patients with Zidovudine Answer Risk for hematologic toxicity is increase by a low granulocyte count; low levels of hemoglobin, b12 or folic acid, concurrent use of drugs that are myelosuppressive, nephrotoxic or toxic to circulating blood cells. Q: High risk patients with Lopinavir Answer Contraindicated for full term infeants up until 14 days after birth, preterm infants. Q: Adverse effect of Albendazole Answer N/V/Abd pain headache temporary hair loss Q: Adverse effect of Pyrantel Pamoate Answer GI disturbance Q: Adverse effect of Mebendazole Answer GI disturbandce Q: Adverse effect of Ivermectin Answer Pruritis, rash, fever, lymph node tenderness, bone and joint pain Q: Adverse effect of Moxidectin Answer Flu like symptoms of the Mazotti response Q: Adverse effect of Lopinavir / Ritonavir Answer Hepatotoxicity, PR/QT prolongation Q: Adverse effect of Saquinavir Answer PR and QT interval prolongation Q: Adverse effect of Enfurvirtide Answer Injection site reactions Q: Is antiretroviral therapy recommended for all HIV patients regardless of CD4 count? Answer Yes including pregnant women Q: What is the safest anthelmintics? Answer Praziquantel Q: How to measure the effect of HIV therapy? Answer Success is indicated by a reduction in plasma HIV RNA CD4 T-Cell Counts - as viral load decreased the cd4 t-cell count will rise indicating some restoration of the immune function. Q: Can you give Ivermetic to a pregnant woman?? Answer NOOOOO! Can you give mebendazole, albendazole or pyrantel pamoate to a pregnant woman? Answer yes but if they on their 2nd or 3rd trimester NEVER on the 1st trimester Can you give Lopinavir/Ritonavir to an infant? Answer NO up until past 14 days after birth Treatment of Glaucoma Answer -Beta-blockers: eye drops, -olol meds (ex. Timolol) - Adrenergics -Prostaglandin (becoming favored) Pros and Cons of beta blocker use for treatment of glaucoma? Can cause minimal disturbance of vision. Can occasionally cause conjunctivitis, blurred vision, photophobia and dry eyes How to treat someone with glaucoma and either asthma or COPD By using a selective beta blocker called Betaxolol. Treatment of Otitis Media Usually resolves in a week on its own ABT for less than 6 months 6 mos - 2 y.o Observation for unilateral AOM with mild symptoms without otorrhea 2 y/o - ABT if illness is severe and observation if not AMOX- is the preferred treatment Treatment for Otitis Externa if bacterial :cleaning and using anti microbial if fungal: cleaning, application of acidifying drops to be applied 3-4 times a day for 7 days. Treatment of Acne Mild: topical benzoyl peroxide and/or topical abt (erythromycin, clindamycin) Moderate: oral systemic therapy w/ abt (tetracycline, minocycline, erythromycin, doxycycline) Severe: oral isotretinoin (accutane) - best tx Treatment of Eczema and complications that may arise Topical immunosuppressants : Tacrolimus (pose a risk for cancer) Pimecrolimus Key ingredient needed in organic sunscreen Oxybenzone Avobenzone Octinoxate Mechanism of Action of Expectorants Renders cough more productive by stimulating the flow of respiratory tract secretions Ex: Guafenesin (Mucinex, Humibid) the-adult-gerontology-primary-care-nurse-practitioner-exam-review-questions-and-verified answers-flash-cards/#:~:text=Original ,Fungal%20Otitis%20Externa%20Treatment,toxicity%20with%20low%20granulocyte%20coun t%2C%20low%20hemoglobin%2C%20or%20folic%20acid%20levels, Rewind%2010%20seconds