Part I: Basic Immunologic Mechanisms
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1. Highlights of Innate and Adaptive Immune Systems q q q q q q
2. Soluble Mediators of the Immune System
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3. Antigens and Antibodies q q
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
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Part II: The Theory of Immunologic and Serologic Procedures
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5. Basic Safety in the Immunology-Serology Laboratory
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6. Quality Assurance and Quality Control Practices
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7. Basic Serologic Laboratory: Techniques and Clinical Applications
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8. Precipitation and Particle Agglutination Methods q q q q
9. Electrophoresis Techniques q
10. Labeling Techniques in Immunoassay q q q
11. Flow Cytometry q
12. Molecular Laboratory Techniques q q
Part III: Immunologic Manifestations of Infectious Diseases
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13. Infectious Diseases: Overview & TORCH Diseases q q q q q
14. Streptococcal Infections q
15. Syphilis
16. Vector-Borne Diseases q
17. Infectious Mononucleosis q
18. Viral Hepatitis q
Part IV: Immune Disorders
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19. Primary and Acquired (Secondary) Immune Deficiencies
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20. Hypersensitivity Reactions q
21. Immunoproliferative Disorders q
22. Tolerance, Autoimmunity and Autoimmune Disorders q q q q
23. Systemic Lupus Erythematosus q q
,24. Rheumatoid Arthritis q
Part V: Transplantation & Tumor Immunology
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25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
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26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
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Part VI: Vaccines
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27. Primer on Vaccines q q
Chapter01:HighlightsoftheInnateandAdaptiveImmuneSystems
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MULTIPLECHOICE q
1. The―father‖ofimmunologyisgenerallyconsideredtobe
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B q
, LouisPasteur isgenerallyconsideredto bethe―fatherofimmunology.‖
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DIF: CognitiveLevel:I q q
2. Anearlyformof immunization was practiced bythe
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a. Romans.
b. Greeks.
c. Chinese.
d. NativeAmericans. q
ANS: C q
Beginningabout 1000AD, theChinesepracticed aformofimmunizationbyinhalingdried powders
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derived from the crusts of smallpox lesions.
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DIF: CognitiveLevel:I q q
3. Aspecific function ofthe immune systemis to
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a. recognize self fromnonself. q q q
b. defendthe bodyagainst nonself. q q q q
c. amplifyspecific functions. q q
d. Both Aand B. q q q
ANS: D q
The functionofthe immunesystemistorecognize self fromnonselfand defend the body against
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nonself. Such a system is necessary for survival. The immune system also has nonspecific effector
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mechanisms that usuallyamplifythe specific functions. Nonspecific componentsoftheimmune
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systeminclude mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors
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(e.g., complement).
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DIF: CognitiveLevel:I q q
4. Anundesirable consequence ofimmunity is
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a. naturalresistance. q
b. acquired resistanceto infectious diseases. q q q q