MneMonics for nAPLeX
2025/2026 coMPLete Questions
And correct Answers (Verified
Answers)|BrAnd new Version!
Below is a comprehensive practice exam covering high-yield mnemonics for the
NAPLEX. Each question includes four answer choices and the verified correct
answer with explanation.
Q1. A pharmacist is reviewing a patient's medication list and notices the patient
takes warfarin. The patient reports starting a new medication for a fungal
infection. Which antifungal drug has the WORST interaction with warfarin,
requiring a 50% warfarin dose reduction?
A. Fluconazole
B. Metronidazole
C. Amiodarone
D. Levofloxacin
Correct Answer: A
Explanation: The FLAMES mnemonic identifies warfarin interactions. Among
these, Amiodarone has the worst interaction (50% warfarin reduction needed),
, followed by Metronidazole (33% reduction). Fluconazole, Levofloxacin,
Erythromycin, and Sulfa-TMP also increase INR .
Q2. A patient on warfarin asks about taking herbal supplements. Which of the
following "5 G's" increases bleeding risk?
A. Ginseng only
B. Ginkgo, Garlic, Ginger, Glucosamine, Ginseng
C. Green tea and St. John's wort
D. Grapefruit and Coenzyme Q10
Correct Answer: B
Explanation: The "5 G's" that increase bleeding risk are Ginkgo, Garlic, Ginger,
Glucosamine, and Ginseng. St. John's wort and green tea decrease bleeding risk,
while grapefruit affects CYP metabolism .
Q3. A patient is prescribed an antibiotic for community-acquired pneumonia.
Which of the following is a "respiratory fluoroquinolone" appropriate for this
indication?
A. Ciprofloxacin
B. Levofloxacin
C. Delafloxacin
D. Ofloxacin
Correct Answer: B
2025/2026 coMPLete Questions
And correct Answers (Verified
Answers)|BrAnd new Version!
Below is a comprehensive practice exam covering high-yield mnemonics for the
NAPLEX. Each question includes four answer choices and the verified correct
answer with explanation.
Q1. A pharmacist is reviewing a patient's medication list and notices the patient
takes warfarin. The patient reports starting a new medication for a fungal
infection. Which antifungal drug has the WORST interaction with warfarin,
requiring a 50% warfarin dose reduction?
A. Fluconazole
B. Metronidazole
C. Amiodarone
D. Levofloxacin
Correct Answer: A
Explanation: The FLAMES mnemonic identifies warfarin interactions. Among
these, Amiodarone has the worst interaction (50% warfarin reduction needed),
, followed by Metronidazole (33% reduction). Fluconazole, Levofloxacin,
Erythromycin, and Sulfa-TMP also increase INR .
Q2. A patient on warfarin asks about taking herbal supplements. Which of the
following "5 G's" increases bleeding risk?
A. Ginseng only
B. Ginkgo, Garlic, Ginger, Glucosamine, Ginseng
C. Green tea and St. John's wort
D. Grapefruit and Coenzyme Q10
Correct Answer: B
Explanation: The "5 G's" that increase bleeding risk are Ginkgo, Garlic, Ginger,
Glucosamine, and Ginseng. St. John's wort and green tea decrease bleeding risk,
while grapefruit affects CYP metabolism .
Q3. A patient is prescribed an antibiotic for community-acquired pneumonia.
Which of the following is a "respiratory fluoroquinolone" appropriate for this
indication?
A. Ciprofloxacin
B. Levofloxacin
C. Delafloxacin
D. Ofloxacin
Correct Answer: B
