UWorld RN NCLEX Prep – 75 Multiple Choice Questions with
Detailed Rationales quiz
Key Terms Explained, Prioritization, Delegation, Pharmacology, Cardiovascular, Respiratory,
Infectious Diseases, Gastrointestinal, Genitourinary & Clinical Judgment Review
Showing 75 questions (same pool and cap as a student attempt). Correct options are pre-
selected and highlighted as on the results page.
Bank category: UWorld RN NCLEX Prep – 75 Multiple Choice Questions with Detailed Rationales
,1 Question 1
Vancomycin is primarily excreted by which organ?
☐ A. Liver
☑ B. Kidneys
☐ C. Lungs
☐ D. Skin
RATIONALE
Vancomycin is mainly cleared through the kidneys. Because of this, kidney function must be
monitored closely to prevent drug buildup and toxicity.
KEY TERMS EXPLAINED
Vancomycin = strong antibiotic often used for serious infections
Excreted = removed from the body
Kidneys = organs that filter waste and many medications
Drug toxicity = harmful effects from excessive medication levels
,2 Question 2
An area of induration of what size is considered a positive PPD response in
any client?
☐ A. > 5 mm
☐ B. > 10 mm
☑ C. > 15 mm
☐ D. > 20 mm
RATIONALE
A PPD test is read by measuring induration, not redness. In clients with no special risk factors, an
induration greater than 15 mm is considered positive. Smaller measurements may be positive in
high-risk groups, but the question asks what size is positive in any client.
KEY TERMS EXPLAINED
PPD = purified protein derivative test used to screen for tuberculosis exposure
Induration = raised, firm swelling at the injection site
Positive PPD = result suggesting TB exposure or infection
Tuberculosis = bacterial infection usually affecting the lungs
, 3 Question 3
How is West Nile virus primarily transmitted?
☐ A. Contaminated water
☑ B. Infected mosquito bite
☐ C. Respiratory droplets
☐ D. Sexual contact
RATIONALE
West Nile virus is primarily spread through the bite of an infected mosquito. Mosquitoes become
infected after feeding on infected birds and can then transmit the virus to humans.
KEY TERMS EXPLAINED
West Nile virus = viral infection spread mainly by mosquitoes
Vector = organism that carries and transmits disease
Mosquito bite = primary route of West Nile transmission
Respiratory droplets = droplets from coughing or sneezing
Detailed Rationales quiz
Key Terms Explained, Prioritization, Delegation, Pharmacology, Cardiovascular, Respiratory,
Infectious Diseases, Gastrointestinal, Genitourinary & Clinical Judgment Review
Showing 75 questions (same pool and cap as a student attempt). Correct options are pre-
selected and highlighted as on the results page.
Bank category: UWorld RN NCLEX Prep – 75 Multiple Choice Questions with Detailed Rationales
,1 Question 1
Vancomycin is primarily excreted by which organ?
☐ A. Liver
☑ B. Kidneys
☐ C. Lungs
☐ D. Skin
RATIONALE
Vancomycin is mainly cleared through the kidneys. Because of this, kidney function must be
monitored closely to prevent drug buildup and toxicity.
KEY TERMS EXPLAINED
Vancomycin = strong antibiotic often used for serious infections
Excreted = removed from the body
Kidneys = organs that filter waste and many medications
Drug toxicity = harmful effects from excessive medication levels
,2 Question 2
An area of induration of what size is considered a positive PPD response in
any client?
☐ A. > 5 mm
☐ B. > 10 mm
☑ C. > 15 mm
☐ D. > 20 mm
RATIONALE
A PPD test is read by measuring induration, not redness. In clients with no special risk factors, an
induration greater than 15 mm is considered positive. Smaller measurements may be positive in
high-risk groups, but the question asks what size is positive in any client.
KEY TERMS EXPLAINED
PPD = purified protein derivative test used to screen for tuberculosis exposure
Induration = raised, firm swelling at the injection site
Positive PPD = result suggesting TB exposure or infection
Tuberculosis = bacterial infection usually affecting the lungs
, 3 Question 3
How is West Nile virus primarily transmitted?
☐ A. Contaminated water
☑ B. Infected mosquito bite
☐ C. Respiratory droplets
☐ D. Sexual contact
RATIONALE
West Nile virus is primarily spread through the bite of an infected mosquito. Mosquitoes become
infected after feeding on infected birds and can then transmit the virus to humans.
KEY TERMS EXPLAINED
West Nile virus = viral infection spread mainly by mosquitoes
Vector = organism that carries and transmits disease
Mosquito bite = primary route of West Nile transmission
Respiratory droplets = droplets from coughing or sneezing
