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kMidterm Exam: Week 1, 2, 3 & 4 k k k k k k k
k 100% Guarantee Pass k k
1.Pharmacodynamics
: Answer What the drug does to the body
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-3 Mechanisms of action
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•Receptor
•Enzyme
•Nonselective Interactions k
2.Enzymes
kAnswer
most frequently seen in relation to the metabolism of drugs
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-act as catalysts in nearly every chemical reaction that takes place in the cells
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-drugs can enhance or inhibit the catalytic actions
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3.Nonselective interactions k
kAnswer
drugs chemically alter or physically interfere with cellular structures or there
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processes
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,•ex: chemotherapy
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4.Patient-specific plan goals k k
kAnswer
cure
-decrease in symptoms k k
-stopping or slowing the disease process
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-preventing disease k
-improved quality of life k k k
5.Types of drug therapy k k k
kAnswer
acute
•tx active disease & sustain life
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-maintenance
•focus on prevention of disease progression
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-supplemental
•medication required for normal body function k k k k k
-palliative
•any tx program designed to provide symptomatic relief of chronic severe pain
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-supportive
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,•maintains integrity of body functions
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-prophylactic
•prevention; immunizations, pre-procedure & postexposure antibiotics
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-empiric
•clinical probability of illness that has not yet been diagnosed; administering broad
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kspectrum antibiotics before culture results
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6.Idiosyncratic effects k
k Answer: unexpected individual responses to medications
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7.Tolerance:
k Answer declining response to a drug
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8.Dependence
k Answer: physiologic or psychologic need for a substance
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9.NIH: dependence vs addiction
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drug dependence
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•a person needs a drug to function normally, abruptly stopping the drug leads to
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kwithdrawal symptoms. k
-drug addiction
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, •the compulsive use of a substance, despite its negative or dangerous effects
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10.drug interactions k
k Answer: • drug-drug
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•food-drug
•additive
•synergistic
•antagonistic
•incompatibility
11.grapefruit juice decreases the metabolism of a number of drugs, includ-
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k ing:
Answer
buspirone
-nefedipine
-statins
12.what food counters the effect of warfarin
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k Answer: leafy dark greens
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-contain vitamin K k k
13.antacids reduce effects of some drugs
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k Answer
(antagonistic interaction) thyroid replacement hormones some
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k antibiotics
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