NR566 | NR566 Advanced Pharmacology for Care
of the Family Wk 4 Final Exam v1 | Questions with
Correct Answers and Expert Explanation for Each
Question | Chamberlain
1. Which of the following is a common side effect of ACE inhibitors that is caused by
the accumulation of bradykinin?
A. Hypokalemia
B. Hyperglycemia
C. Dry cough
D. Tachycardia
Correct Answer: C
Expert Explanation: ACE inhibitors block the conversion of angiotensin I to
angiotensin II, leading to vasodilation. This process also inhibits the breakdown of
bradykinin, which can accumulate in the lungs. This accumulation is the primary
cause of the persistent dry cough reported by many patients.
2. When prescribing a statin for hyperlipidemia, which laboratory value must be
assessed if the patient reports significant muscle pain?
A. Serum amylase
B. Hemoglobin A1c
,C. Blood urea nitrogen (BUN)
D. Creatine kinase (CK)
Correct Answer: D
Expert Explanation: Statins can occasionally cause myopathy or the more severe
rhabdomyolysis. Creatine kinase levels are measured to assess for muscle damage in
symptomatic patients. This assessment helps the provider decide whether to
discontinue the medication to prevent renal failure.
3. What is the primary mechanism of action for Warfarin in the prevention of blood
clots?
A. Direct inhibition of Factor Xa
B. Binding to antithrombin III
C. Inhibition of Vitamin K epoxide reductase
D. Blockade of ADP receptors
Correct Answer: C
Expert Explanation: Warfarin works by interfering with the synthesis of Vitamin K-
dependent clotting factors. It specifically inhibits the enzyme Vitamin K epoxide
reductase, which is necessary for recycling Vitamin K. This leads to a reduction in
factors II, VII, IX, and X over several days.
,4. A patient with asthma requires a medication for hypertension. Which of the
following beta-blockers is the safest choice?
A. Propranolol
B. Nadolol
C. Metoprolol
D. Timolol
Correct Answer: C
Expert Explanation: Metoprolol is a cardioselective beta-1 blocker, meaning it
primarily affects the heart rather than the lungs. Non-selective beta-blockers like
propranolol can block beta-2 receptors in the bronchioles, leading to bronchospasm.
Providers should still monitor asthma patients closely even when using selective
agents.
5. Which of the following electrolytes is most likely to be elevated in a patient taking
Spironolactone?
A. Sodium
B. Magnesium
C. Potassium
D. Calcium
, Correct Answer: C
Expert Explanation: Spironolactone is a potassium-sparing diuretic that acts as an
aldosterone antagonist in the distal tubule. By blocking aldosterone, the kidneys
retain potassium while excreting sodium and water. Patients must be monitored for
hyperkalemia, especially if they are also taking ACE inhibitors.
6. What is the classic visual symptom associated with Digoxin toxicity?
A. Blurred vision
B. Yellow-green halos around lights
C. Total loss of peripheral vision
D. Double vision
Correct Answer: B
Expert Explanation: Digoxin toxicity can present with gastrointestinal distress,
arrhythmias, and neurological symptoms. A classic sign of toxicity is xanthopsia,
where patients see yellow or green halos around objects. This occurs because
digoxin affects the electrical activity within the retina.
7. A patient taking Amiodarone for atrial fibrillation should have which of the
following monitored regularly?
A. Daily weights
of the Family Wk 4 Final Exam v1 | Questions with
Correct Answers and Expert Explanation for Each
Question | Chamberlain
1. Which of the following is a common side effect of ACE inhibitors that is caused by
the accumulation of bradykinin?
A. Hypokalemia
B. Hyperglycemia
C. Dry cough
D. Tachycardia
Correct Answer: C
Expert Explanation: ACE inhibitors block the conversion of angiotensin I to
angiotensin II, leading to vasodilation. This process also inhibits the breakdown of
bradykinin, which can accumulate in the lungs. This accumulation is the primary
cause of the persistent dry cough reported by many patients.
2. When prescribing a statin for hyperlipidemia, which laboratory value must be
assessed if the patient reports significant muscle pain?
A. Serum amylase
B. Hemoglobin A1c
,C. Blood urea nitrogen (BUN)
D. Creatine kinase (CK)
Correct Answer: D
Expert Explanation: Statins can occasionally cause myopathy or the more severe
rhabdomyolysis. Creatine kinase levels are measured to assess for muscle damage in
symptomatic patients. This assessment helps the provider decide whether to
discontinue the medication to prevent renal failure.
3. What is the primary mechanism of action for Warfarin in the prevention of blood
clots?
A. Direct inhibition of Factor Xa
B. Binding to antithrombin III
C. Inhibition of Vitamin K epoxide reductase
D. Blockade of ADP receptors
Correct Answer: C
Expert Explanation: Warfarin works by interfering with the synthesis of Vitamin K-
dependent clotting factors. It specifically inhibits the enzyme Vitamin K epoxide
reductase, which is necessary for recycling Vitamin K. This leads to a reduction in
factors II, VII, IX, and X over several days.
,4. A patient with asthma requires a medication for hypertension. Which of the
following beta-blockers is the safest choice?
A. Propranolol
B. Nadolol
C. Metoprolol
D. Timolol
Correct Answer: C
Expert Explanation: Metoprolol is a cardioselective beta-1 blocker, meaning it
primarily affects the heart rather than the lungs. Non-selective beta-blockers like
propranolol can block beta-2 receptors in the bronchioles, leading to bronchospasm.
Providers should still monitor asthma patients closely even when using selective
agents.
5. Which of the following electrolytes is most likely to be elevated in a patient taking
Spironolactone?
A. Sodium
B. Magnesium
C. Potassium
D. Calcium
, Correct Answer: C
Expert Explanation: Spironolactone is a potassium-sparing diuretic that acts as an
aldosterone antagonist in the distal tubule. By blocking aldosterone, the kidneys
retain potassium while excreting sodium and water. Patients must be monitored for
hyperkalemia, especially if they are also taking ACE inhibitors.
6. What is the classic visual symptom associated with Digoxin toxicity?
A. Blurred vision
B. Yellow-green halos around lights
C. Total loss of peripheral vision
D. Double vision
Correct Answer: B
Expert Explanation: Digoxin toxicity can present with gastrointestinal distress,
arrhythmias, and neurological symptoms. A classic sign of toxicity is xanthopsia,
where patients see yellow or green halos around objects. This occurs because
digoxin affects the electrical activity within the retina.
7. A patient taking Amiodarone for atrial fibrillation should have which of the
following monitored regularly?
A. Daily weights
