HESI Pharmacology Exam Study
Guide | Nursing Pharmacology
Practice Test
written by
trustednurse
The Marketplace to Buy and Sell your Study Material
At Stuvia, you will find the best notes, summaries, flashcards & other study material. Search for your
school or uni and find the study material you need.
www.stuvia.com
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
HESI Pharmacology Exam Practice NEWEST 2025-2026
COMPLETE QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED
A+||BRAND NEW VERSION!!
A healthcare provider prescribes cephalexin monohydrate (Keflex) for a client
with a postoperative infection. It is most important for the nurse to assess for
what additional drug allergy before administering this prescription?
A) Penicillins.
B) Aminoglycosides.
C) Erythromycins.
D) Sulfonamides. - CORRECT ANSWER- A) Penicillins.
Cross-allergies exist between penicillins (A) and cephalosporins, such as
cephalexin monohydrate (Keflex), so checking for penicillin allergy is a wise
precaution before administering this drug.
Which nursing intervention is most important when caring for a client receiving
the antimetabolite cytosine arabinoside (Arc-C) for chemotherapy?
A) Hydrate the client with IV fluids before and after infusion.
B) Assess the client for numbness and tingling of extremities.
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
C) Inspect the client's oral mucosa for ulcerations.
D) Monitor the client's urine pH for increased acidity. - CORRECT ANSWER- C) Inspect
the client's oral mucosa for ulcerations.
Cytosine arabinoside (Arc-C) affects the rapidly growing cells of the body,
therefore stomatitis and mucosal ulcerations are key signs of antimetabolite
toxicity (C). (A, B, and D) are not typical interventions associated with the
administration of antimetabolites.
When assessing an adolescent who recently overdosed on acetaminophen
(Tylenol), it is most important for the nurse to assess for pain in which area of the
body?
A) Flank.
B) Abdomen.
C) Chest.
D) Head. - CORRECT ANSWER- B) Abdomen.
Acetaminophen toxicity can result in liver damage; therefore, it is especially
important for the nurse to assess for pain in the right upper quadrant of the
abdomen (B), which might indicate liver damage. (A, C, and D) are not areas
where pain would be anticipated.
An adult client is given a prescription for a scopolamine patch (Transderm Scop)
to prevent motion sickness while on a cruise. Which information should the nurse
provide to the client?
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
A) Apply the patch at least 4 hours prior to departure.
B) Change the patch every other day while on the cruise.
C) Place the patch on a hairless area at the base of the skull.
D) Drink no more than 2 alcoholic drinks during the cruise. - CORRECT ANSWER- A)
Apply the patch at least 4 hours prior to departure.
Scopolamine, an anticholinergic agent, is used to prevent motion sickness and has
a peak onset in 6 hours, so the client should be instructed to apply the patch at
least 4 hours before departure (A) on the cruise ship. The duration of the
transdermal patch is 72 hours, so (B) is not needed. Scolopamine blocks
muscarinic receptors in the inner ear and to the vomiting center, so the best
application site of the patch is behind the ear, not at the base of the skull (C).
Anticholinergic medications are CNS depressants, so the client should be
instructed to avoid alcohol (D) while using the patch.
The nurse is reviewing the use of the patient-controlled analgesia (PCA) pump
with a client in the immediate postoperative period. The client will receive
morphine 1 mg IV per hour basal rate with 1 mg IV every 15 minutes per PCA to
total 5 mg IV maximally per hour. What assessment has the highest priority
before initiating the PCA pump?
A) The expiration date on the morphine syringe in the pump.
B) The rate and depth of the client's respirations.
C) The type of anesthesia used during the surgical procedure.
D) The client's subjective and objective signs of pain. - CORRECT ANSWER- B) The
rate and depth of the client's respirations.
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
Guide | Nursing Pharmacology
Practice Test
written by
trustednurse
The Marketplace to Buy and Sell your Study Material
At Stuvia, you will find the best notes, summaries, flashcards & other study material. Search for your
school or uni and find the study material you need.
www.stuvia.com
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
HESI Pharmacology Exam Practice NEWEST 2025-2026
COMPLETE QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED
A+||BRAND NEW VERSION!!
A healthcare provider prescribes cephalexin monohydrate (Keflex) for a client
with a postoperative infection. It is most important for the nurse to assess for
what additional drug allergy before administering this prescription?
A) Penicillins.
B) Aminoglycosides.
C) Erythromycins.
D) Sulfonamides. - CORRECT ANSWER- A) Penicillins.
Cross-allergies exist between penicillins (A) and cephalosporins, such as
cephalexin monohydrate (Keflex), so checking for penicillin allergy is a wise
precaution before administering this drug.
Which nursing intervention is most important when caring for a client receiving
the antimetabolite cytosine arabinoside (Arc-C) for chemotherapy?
A) Hydrate the client with IV fluids before and after infusion.
B) Assess the client for numbness and tingling of extremities.
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
C) Inspect the client's oral mucosa for ulcerations.
D) Monitor the client's urine pH for increased acidity. - CORRECT ANSWER- C) Inspect
the client's oral mucosa for ulcerations.
Cytosine arabinoside (Arc-C) affects the rapidly growing cells of the body,
therefore stomatitis and mucosal ulcerations are key signs of antimetabolite
toxicity (C). (A, B, and D) are not typical interventions associated with the
administration of antimetabolites.
When assessing an adolescent who recently overdosed on acetaminophen
(Tylenol), it is most important for the nurse to assess for pain in which area of the
body?
A) Flank.
B) Abdomen.
C) Chest.
D) Head. - CORRECT ANSWER- B) Abdomen.
Acetaminophen toxicity can result in liver damage; therefore, it is especially
important for the nurse to assess for pain in the right upper quadrant of the
abdomen (B), which might indicate liver damage. (A, C, and D) are not areas
where pain would be anticipated.
An adult client is given a prescription for a scopolamine patch (Transderm Scop)
to prevent motion sickness while on a cruise. Which information should the nurse
provide to the client?
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
A) Apply the patch at least 4 hours prior to departure.
B) Change the patch every other day while on the cruise.
C) Place the patch on a hairless area at the base of the skull.
D) Drink no more than 2 alcoholic drinks during the cruise. - CORRECT ANSWER- A)
Apply the patch at least 4 hours prior to departure.
Scopolamine, an anticholinergic agent, is used to prevent motion sickness and has
a peak onset in 6 hours, so the client should be instructed to apply the patch at
least 4 hours before departure (A) on the cruise ship. The duration of the
transdermal patch is 72 hours, so (B) is not needed. Scolopamine blocks
muscarinic receptors in the inner ear and to the vomiting center, so the best
application site of the patch is behind the ear, not at the base of the skull (C).
Anticholinergic medications are CNS depressants, so the client should be
instructed to avoid alcohol (D) while using the patch.
The nurse is reviewing the use of the patient-controlled analgesia (PCA) pump
with a client in the immediate postoperative period. The client will receive
morphine 1 mg IV per hour basal rate with 1 mg IV every 15 minutes per PCA to
total 5 mg IV maximally per hour. What assessment has the highest priority
before initiating the PCA pump?
A) The expiration date on the morphine syringe in the pump.
B) The rate and depth of the client's respirations.
C) The type of anesthesia used during the surgical procedure.
D) The client's subjective and objective signs of pain. - CORRECT ANSWER- B) The
rate and depth of the client's respirations.
Downloaded by: bismarckmensah | Want to earn $1.236
Distribution of this document is illegal extra per year?
