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ATI Pharmacology 1301 Exam 2 Review 2026 | NCLEX Practice Questions & Rationales

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This ATI Pharmacology 1301 Exam 2 Review 2026 resource is designed to help nursing students prepare effectively using NCLEX-style practice questions with clear answers and detailed rationales. The content focuses on key pharmacology concepts including drug classifications, mechanisms of action, side effects, safe medication administration, and patient education. Questions are structured to reflect exam-style scenarios, helping learners strengthen critical thinking, improve knowledge retention, and build confidence. Each question includes detailed explanations to enhance understanding and support effective revision. This resource is ideal for students preparing for pharmacology exams and the NCLEX-RN, offering a focused and practical study tool.

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Institution
Advanced Pharmacology
Course
Advanced pharmacology

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lOMoARcPSD|64668917




ATI PHARMACOLOGY 1301 TEST EXAM 2 REVIEW LATEST
2026 STUDY QUESTIONS WITH VERIFIED CORRECT
ANSWERS 100% GUARANTEED PASS | RATED A+
The nurse provides client teaching about use of levodopa for treatment of Parkinson disease.
What statement by the client would indicate a good understanding of levodopa? (select all that
apply)

a. "I'll know within about a year whether this drug has cured my Parkinson disease."

b. " I will not stop this medication suddenly"

c. "I should avoid exercising while taking this drug so that I don't get injured."

d. "I should take this drug with food to avoid an upset stomach."

e. "I will avoid foods high in Pyridoxine (vitamin B6)"

f. "I will notify the provider if I have involuntary movements or if the drug stops working" -
Answer>>> b. " I will not stop this medication suddenly"

d. "I should take this drug with food to avoid an upset stomach."

e. "I will avoid foods high in Pyridoxine (vitamin B6)"

f. "I will notify the provider if I have involuntary movements or if the drug stops working"

An older client is taking an anticholinergic agent. After teaching the client about the drug, which
client statement indicates the need for additional teaching?

a. "I should make sure that I drink plenty of fluids."

b. "I need to exercise frequently outside in the warm weather."

c. "I should avoid driving if I feel light-headed or dizzy."

d. "I should eat plenty of fiber to prevent constipation." - Answer>>> b. "I need to exercise
frequently outside in the warm weather."

, lOMoARcPSD|64668917




A client with acute migraines has been advised by the health care provider to use over-the-
counter naproxen sodium. What education should the nurse provide?

a. Take the medication with food to avoid GI complications.

b. Take the medication at bedtime to reduce the effects of drowsiness.

c. Avoid calcium supplements or antacids containing calcium.

d. Complete liver testing before beginning treatment. - Answer>>> a. Take the medication with
food to avoid GI complications.

The nurse is caring for a client who is receiving the cholinergic drug neostigmine for the
treatment of myasthenia gravis. The nurse is aware that a potential complication of the treatment
is cholinergic crisis, which is characterized by which event?



a. excessive stimulation of the parasympathetic nervous system

b. excessive stimulation of the sympathetic nervous system

c. hypertension and respiratory failure

d. stronger skeletal muscle contractions - Answer>>> a. excessive stimulation of the
parasympathetic nervous system

A client's family asks why the nurse has placed suction equipment in the room immediately after
administering a dose of naloxone. Which explanation by the nurse is correct?

a. After surgery, a client may feel nauseated as a side effect of the anesthesia.

b. Abrupt reversal of opioid-induced respiratory depression may cause vomiting.

c. This is a precaution in case the client begins to choke when resuming a general diet.

d. Suction equipment should be placed in all client rooms as a standard of care postoperatively. -
Answer>>> b. Abrupt reversal of opioid-induced respiratory depression may cause vomiting.

, lOMoARcPSD|64668917




The nurse assessed a client at 0800 and obtained a blood pressure of 111/70 mmHg. Two hours
later, the client's blood pressure has increased to 130/81 mmHg. The nurse should attribute this
change to what action within the autonomic nervous system?

a. Stimulation of beta-receptors

b. Antagonism of alpha-receptors

c. Decreasing levels of acetylcholinesterase

d. Stimulation of nicotinic receptors - Answer>>> b. Stimulation of beta-receptors

The nurse is scheduled to administer pancuronium, a neuromuscular-blocking medication, to a
client receiving mechanical ventilation. The nurse would predict which receptor subtype(s) to be
activated resulting in a stimulatory response?

a. All muscarinic receptors

b. specifically nicotinicn receptors

c. specifically nicotinicm receptors

Both muscarinic and nicotinic receptors - Answer>>> b. specifically nicotinicn receptors

While reviewing a client record, the nurse sees that the client has a history of chronic insomnia.
What assumption can the nurse have regarding the client?

a. The client has been experiencing dysfunctional sleep for more than 1 month.

b. The client has periods of alternating deep and light sleep.

c. The client needs pharmacological assistance to go to sleep.

d. The client is experiencing an underlying serious illness. - Answer>>> a. The client has been
experiencing dysfunctional sleep for more than 1 month.

A male client took zolpidem daily for 1 week with good response, then stopped the medication.
Two days later, he returns to the office stating that his insomnia is worse than it ever was. The
nurse is responsible for the development of a teaching plan for the client, including adverse
reactions. After 1 week of regular use, which adverse reaction may occur with zolpidem?

, lOMoARcPSD|64668917




a. Chronic insomnia

b. Short-term insomnia

c. Rebound insomnia

d. Long-term insomnia - Answer>>> c. Rebound insomnia

A client with type 1 diabetes mellitus has been dealing with feelings of depression for the last
month, and the health care provider has elected to start this client on fluoxetine. What client
teaching is most important for the nurse to share with this client?

a. "You will probably need to increase your usual insulin dosage."

b. "Increase your monitoring of your blood sugar because there is an increased chance of
hypoglycemia."

c. "Double the carbohydrates you eat daily to prevent hypoglycemia from occurring."

d. "Decrease your calorie intake by one half by skipping all in-between meals." - Answer>>> b.
"Increase your monitoring of your blood sugar because there is an increased chance of
hypoglycemia."

The nurse administers a medication that stimulates the muscarinic receptors. What
manifestations should the nurse expect to assess in this client?

a. pupil dilation

b. increased activity of bowel sounds

c. increased heart rate

d. muscle contractions - Answer>>> b. increased activity of bowel sounds



Feedback: Stimulation of muscarinic receptors increases gastrointestinal (GI) motility which
would cause increased activity of bowel sounds. Other effects include pupil constriction,
increased urinary bladder contraction, and a slowing of the heart rate. Stimulation of nicotinic
receptors cause muscle contractions.

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Institution
Advanced pharmacology
Course
Advanced pharmacology

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Uploaded on
April 30, 2026
Number of pages
33
Written in
2025/2026
Type
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Questions & answers

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